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Journal of Liquid Chromatography & Related Technologies Volume 36, 2012 - Issue 1
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Original Articles

IDENTIFICATION OF PRASUGREL (AN ANTIPLATELET DRUG) IMPURITIES BY LC-MS/MS, RAPID DETERMINATION OF PRASUGREL HYDROCHLORIDE-RELATED SUBSTANCES, AND DEGRADATION PRODUCTS IN ACTIVE PHARMACEUTICAL INGREDIENT AND PHARMACEUTICAL DOSAGE FORMS BY STABILITY INDICATING ULTRA-PERFORMANCE LIQUID CHROMATOGRAPHIC METHOD

V. Malati Dr. Reddy's Laboratories Ltd. Active Pharmaceutical Ingredients, IPDO, Hyderabad, Andhra Pradesh, India; Centre for Chemical Science and Technology, Institute of Science and Technology, J. N. T. University, Hyderabad, Andhra Pradesh, IndiaCorrespondence[email protected] [email protected]
,
A. Raghupatireddy Dr. Reddy's Laboratories Ltd. Active Pharmaceutical Ingredients, IPDO, Hyderabad, Andhra Pradesh, India
,
K. Mukkanti Centre for Chemical Science and Technology, Institute of Science and Technology, J. N. T. University, Hyderabad, Andhra Pradesh, India
&
M. V. Suryanarayana Matrix Laboratories Limited, Anrich Industrial Estate, Bollaram, Andhra Pradesh, India
Pages 61-79 | Published online: 10 Jan 2013

Citations (8)

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Sharif Arar, Kamal Sweidan & Sami Qasem. (2018) Identification and characterization of the degradation products of prasugrel hydrochloride tablets using LC-MS technique. Journal of Liquid Chromatography & Related Technologies 41:1, pages 14-23.
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Articles from other publishers (7)

Nayan S. Gadhari, Suyog S. Patil, Jayram V. Gholave, Amol V. Pansare, Viswanath R. Patil & Sharad S. Upadhyay. (2022) Simultaneous Determination of Prasugrel and its Process Related Impurities and Degradation Products in Bulk Drug Substances by RPLC-UV. Current Chromatography 9:1.
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Steven W. Baertschi, Lindsay Maxwell-Backer, Matthew Clemens, Tim A. Smitka, Jerry R. Draper, K. Wayne Taylor, Andreas Kaerner & Patrick J. Jansen. (2019) The Degradation Chemistry of Prasugrel Hydrochloride: Part 1—Drug Substance. Journal of Pharmaceutical Sciences 108:9, pages 2842-2857.
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Sreekanth Kakarla, Peda Varma Datla, Geetha kodali & Ganapaty Seru. (2016) Analysis of prasugrel active metabolite R-138727 in human plasma: a sensitive, highly selective and fast LC–MS/MS method. Journal of Chromatography B 1020, pages 103-110.
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Dilip Kumar Singh, Archana Sahu, Tarun Handa, Mallikarjun Narayanam & Saranjit Singh. (2015) Study of the forced degradation behavior of prasugrel hydrochloride by liquid chromatography with mass spectrometry and liquid chromatography with NMR detection and prediction of the toxicity of the characterized degradation products. Journal of Separation Science 38:17, pages 2995-3005.
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Mahmoud M.H. Al Omari, Nidal A. Qinna, Iyad S. Rashid, Khaldoun A. Al-Sou’od & Adnan A. Badwan. 2015. 195 320 .
Mehmet Gumustas, Sevinc Kurbanoglu, Bengi Uslu & Sibel A. Ozkan. (2013) UPLC versus HPLC on Drug Analysis: Advantageous, Applications and Their Validation Parameters. Chromatographia 76:21-22, pages 1365-1427.
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Annu Pandey, Kshiti Singh & Antony Nitin Raja. (2022) Mesoporous Carbon-Based Sensor for Quantification of Prasugrel in Solubilized System. SSRN Electronic Journal.
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