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Journal of Liquid Chromatography Volume 15, 1992 - Issue 6-7
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Original Articles

Characterization of Humanized Anti-Tac Monoclonal Antibody by Traditional Separation Techniques and Capillary Electrophoresis

Maureen A. Costello Pharmaceutical Quality Control and Assurance, Hoffmann-La Roche Inc., Nutley, New Jersey, 07110
,
Christine Woititz Pharmaceutical Quality Control and Assurance, Hoffmann-La Roche Inc., Nutley, New Jersey, 07110
,
Joseph De Feo Pharmaceutical Quality Control and Assurance, Hoffmann-La Roche Inc., Nutley, New Jersey, 07110
,
Donna Stremlo Pharmaceutical Quality Control and Assurance, Hoffmann-La Roche Inc., Nutley, New Jersey, 07110
,
Lan-Fun L. Wen Pharmaceutical Quality Control and Assurance, Hoffmann-La Roche Inc., Nutley, New Jersey, 07110
,
David J. Palling Pharmaceutical Quality Control and Assurance, Hoffmann-La Roche Inc., Nutley, New Jersey, 07110
,
Khurshid Iqbal Pharmaceutical Research and Development, Hoffmann-La Roche Inc., Nutley, New Jersey, 07110
&
Norberto A. Guzman Pharmaceutical Research and Development, Hoffmann-La Roche Inc., Nutley, New Jersey, 07110
 show all
Pages 1081-1097 | Published online: 23 Sep 2006

Citations (25)

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Read on this site (2)

Jiaqi Wu & Janusz Pawliszyn. (1993) Sensitivity Enhancement Methods for Capillary Isoelectric Focusing/ Concentration Gradient Imaging System. Journal of Liquid Chromatography 16:17, pages 3675-3687.
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Jiaqi Wu & Janusz Pawliszyn. (1993) Capillary Isoelectric Focusing with Imaging Detection. Journal of Liquid Chromatography 16:9-10, pages 1891-1902.
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Articles from other publishers (23)

Norberto A. Guzman & Daniel E. Guzman. (2021) Immunoaffinity Capillary Electrophoresis in the Era of Proteoforms, Liquid Biopsy and Preventive Medicine: A Potential Impact in the Diagnosis and Monitoring of Disease Progression. Biomolecules 11:10, pages 1443.
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Tingting Wang, Sangeeta B. Joshi, Ozan S. Kumru, Srivalli Telikepalli, C. Russell Middaugh & David B. Volkin. 2013. Biophysics for Therapeutic Protein Development. Biophysics for Therapeutic Protein Development 205 243 .
C. Andrew Boswell, Devin B. Tesar, Kiran Mukhyala, Frank-Peter Theil, Paul J. Fielder & Leslie A. Khawli. (2010) Effects of Charge on Antibody Tissue Distribution and Pharmacokinetics. Bioconjugate Chemistry 21:12, pages 2153-2163.
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Hongcheng Liu, Georgeen Gaza-Bulseco, Dinesh Faldu, Chris Chumsae & Joanne Sun. (2008) Heterogeneity of Monoclonal Antibodies. Journal of Pharmaceutical Sciences 97:7, pages 2426-2447.
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Jiaqi Wu & Tiemin Huang. (2006) Peak identification in capillary isoelectric focusing using the concept of relative peak position as determined by two isoelectric point markers. ELECTROPHORESIS 27:18, pages 3584-3590.
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M. A. Schenerman & S. H. Bowen. 2001. CE in Biotechnology: Practical Applications for Protein and Peptide Analyses. CE in Biotechnology: Practical Applications for Protein and Peptide Analyses 66 74 .
Christina Gendreau, Ira Krull & Hong Jian Dai. 2000. Analytical Techniques in Combinatorial Chemistry. Analytical Techniques in Combinatorial Chemistry.
H.J Dai, G Li & I.S Krull. (1998) Separation and quantitation of monoclonal antibodies in cell growth medium using capillary zone electrophoresis. Journal of Pharmaceutical and Biomedical Analysis 17:6-7, pages 1143-1153.
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G Hunt, T Hotaling & A.B Chen. (1998) Validation of a capillary isoelectric focusing method for the recombinant monoclonal antibody C2B8. Journal of Chromatography A 800:2, pages 355-367.
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I.S. Krull, X. Liu, J. Dai, C. Gendreau & G. Li. (1997) HPCE methods for the identification and quantitation of antibodies, their conjugates and complexes. Journal of Pharmaceutical and Biomedical Analysis 16:3, pages 377-393.
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Huey G Lee. (1997) Rapid high-performance isoelectric focusing of monoclonal antibodies in uncoated fused-silica capillaries. Journal of Chromatography A 790:1-2, pages 215-223.
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Norberto A. Guzman, SungAe S. Park, Daniel Schaufelberger, Luis Hernandez, Ximena Paez, Pedro Rada, Andy J. Tomlinson & Stephen Naylor. (1997) New approaches in clinical chemistry: on-line analyte concentration and microreaction capillary electrophoresis for the determination of drugs, metabolic intermediates, and biopolymers in biological fluids. Journal of Chromatography B: Biomedical Sciences and Applications 697:1-2, pages 37-66.
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T. Pritchett. 1996. Handbook of Capillary Electrophoresis Applications. Handbook of Capillary Electrophoresis Applications 240 254 .
G. Hunt, K.G. Moorhouse & A.B. Chen. (1996) Capillary isoelectric focusing and sodium dodecyl sulfate-capillary gel electrophoresis of recombinant humanized monoclonal antibody HER2. Journal of Chromatography A 744:1-2, pages 295-301.
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X. Liu, Z. Sosic & I.S. Krull. (1996) Capillary isoelectric focusing as a tool in the examination of antibodies, peptides and proteins of pharmaceutical interest. Journal of Chromatography A 735:1-2, pages 165-190.
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Thomas J. Pritchett. (2005) Capillary isoelectric focusing of proteins. ELECTROPHORESIS 17:7, pages 1195-1201.
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Jiaqi Wu & Janusz Pawliszyn. (2005) Application of capillary isoelectric focusing with absorption imaging detection to the quantitative determination of human hemoglobin variants. ELECTROPHORESIS 16:1, pages 670-673.
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Jiaqi. Wu & Janusz. Pawliszyn. (2002) Dual Detection for Capillary Isoelectric Focusing with Refractive Index Gradient and Absorption Imaging Detectors. Analytical Chemistry 66:6, pages 867-873.
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Andrew J.S. Jones. (1993) Analysis of polypeptides and proteins. Advanced Drug Delivery Reviews 10:1, pages 29-90.
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Jiaqi Wu & Janusz Pawliszyn. (2005) Fast analysis of proteins by isoelectric focusing performed in capillary array detected with concentration gradient imaging system. ELECTROPHORESIS 14:1, pages 469-474.
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Jeff R. Mazzeo, Jay A. Martineau & Ira S. Krull. (1992) Performance of isoelectric focusing in uncoated and commercially available coated capillaries. Methods 4:3, pages 205-212.
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Norberto A. Guzman, John Moschera, Khurshid Iqbal & A. Waseem Malick. (1992) Effect of buffer constituents on the determination of therapeutic proteins by capillary electrophoresis. Journal of Chromatography A 608:1-2, pages 197-204.
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Norberto A. Guzman, John Moschera, Carole A. Bailey, Khurshid Iqbal & A.Waseem Malick. (1992) Assay of protein drug substances present in solution mixtures by fluorescamine derivatization and capillary electrophoresis. Journal of Chromatography A 598:1, pages 123-131.
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