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Journal of Liquid Chromatography Volume 16, 1993 - Issue 12
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Original Articles

A Stereospecific Microassay for the Determination of Morphine-6-β-D-Glucuronide and other Active Morphine Metabolites in the Neonatal Guinea Pig

Laine J. Murphey Department of Pharmacology, L221, School of Medicine Oregon Health Sciences University, 3181 S. W. Sam Jackson Park Road, Portland, Oregon, 97201-3098
&
George D. Olsen Department of Pharmacology, L221, School of Medicine Oregon Health Sciences University, 3181 S. W. Sam Jackson Park Road, Portland, Oregon, 97201-3098
Pages 2545-2561 | Received 17 Nov 1992, Accepted 30 Nov 1992, Published online: 23 Sep 2006

Citations (14)

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Daniel Bourquin, Petra Bundeli, Thomas Lehmann & Rudolf Brenneisen. (1999) DIACETYLMORPHINE AND ITS METABOLITES IN PLASMA BY HPLC WITH DIODE-ARRAY AND ATMOSPHERIC PRESSURE IONIZATION MASS SPECTROMETRIC DETECTION. Journal of Liquid Chromatography & Related Technologies 22:17, pages 2663-2674.
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Robert W. Milne, Roger L. Nation & Andrew A. Somogyi. (1996) The Disposition of Morphine and Its 3- and 6-Glucuronide Metabolites in Humans and Animals, and the Importance of the Metabolites to the Pharmacological Effects of Morphine. Drug Metabolism Reviews 28:3, pages 345-472.
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Georgios Theodoridis, Ioannis Papadoyannis, Helen Tsoukali-Papadopoulou & Georgios Vasilikiotis. (1995) A Comparative Study of Different Solid Phase Extraction Procedures for the Analysis of Alkaloids of Forensic Interest in Biological Fluids by RP-HPLC/Diode Array. Journal of Liquid Chromatography 18:10, pages 1973-1995.
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Articles from other publishers (11)

E. Smet, G. Van der Weken, W. R. G. Baeyens & J. P. Remon. (2001) A validated HPLC method for assay of morphine hydrochloride and hydromorphone hydrochloride in pharmaceutical injections. Chromatographia 53:1-2, pages 35-39.
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Maciej J. Bogusz. 2000. Forensic Science. Forensic Science 3 65 .
Shuuji Hara, Sakiko Mochinaga, Misa Fukuzawa, Nobufumi Ono & Takeshi Kuroda. (1999) Simple and highly sensitive determination of morphine in rat plasma by liquid chromatography with fluorescence detection. Analytica Chimica Acta 387:2, pages 121-126.
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Simona Pichini, Ilaria Altieri, Manuela Pellegrini, Piergiorgio Zuccaro & Roberta Pacifici. (1999) The role of liquid chromatography-mass spectrometry in the determination of heroin and related opioids in biological fluids. Mass Spectrometry Reviews 18:2, pages 119-130.
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Colin T Bedford. (1998) Glucuronic acid conjugates. Journal of Chromatography B: Biomedical Sciences and Applications 717:1-2, pages 313-326.
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M Zheng, K.M McErlane & M.C Ong. (1998) High-performance liquid chromatography-mass spectrometry-mass spectrometry analysis of morphine and morphine metabolites and its application to a pharmacokinetic study in male Sprague–Dawley rats. Journal of Pharmaceutical and Biomedical Analysis 16:6, pages 971-980.
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D. Bourquin, T. Lehmann, R. Hämmig, M. Bührer & R. Brenneisen. (1997) High-performance liquid chromatographic monitoring of intravenously administered diacetylmorphine and morphine and their metabolites in human plasma. Journal of Chromatography B: Biomedical Sciences and Applications 694:1, pages 233-238.
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O.K. Rønnekleiv, M.A. Bosch, M.J. Cunningham, E.J. Wagner, D.K. Grandy & M.J. Kelly. (1996) Downregulation of μ-opioid receptor mRNA in the mediobasal hypothalamus of the female guinea pig following morphine treatment. Neuroscience Letters 216:2, pages 129-132.
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Mark R. Taylor, Steven A. Westwood & David Perrett. (1996) Determination of phase II drug metabolites in equine urine by micellar electrokinetic capillary chromatography. Journal of Chromatography A 745:1-2, pages 155-163.
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Jörg Huwyler, Stefan Rufer, Ernst Küsters & Jürgen Drewe. (1995) Rapid and highly automated determination of morphine and morphine glucuronides in plasma by on-line solid-phase extraction and column liquid chromatography. Journal of Chromatography B: Biomedical Sciences and Applications 674:1, pages 57-63.
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LJ Murphey & GD Olsen. (1994) Distribution of morphine-6-β-D-glucuronide across the blood-brain barrier of neonatal guinea pigs. Regulatory Peptides 54:1, pages 207-208.
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