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Journal of Liquid Chromatography Volume 16, 1993 - Issue 9-10: Selected Papers from the Third Annual Frederick Conference on Capillary Electrophoresis
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Original Articles

Pulsed UV Laser-Induced Fluorescence Detection of Native Peptides and Proteins in Capillary Electrophoresis

King C. Chan Program Resources, Inc./DynCorp, NCI-Frederick Cancer Research and Development Center, P.O. Box B, Frederick, Maryland, 21702
,
George M. Janini Program Resources, Inc./DynCorp, NCI-Frederick Cancer Research and Development Center, P.O. Box B, Frederick, Maryland, 21702
,
Gary M. Muschik Program Resources, Inc./DynCorp, NCI-Frederick Cancer Research and Development Center, P.O. Box B, Frederick, Maryland, 21702
&
Haleem J. Issaq Program Resources, Inc./DynCorp, NCI-Frederick Cancer Research and Development Center, P.O. Box B, Frederick, Maryland, 21702
Pages 1877-1890 | Published online: 23 Sep 2006

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Haleem J. Issaq. (2002) THIRTY-FIVE YEARS OF CAPILLARY ELECTROPHORESIS: ADVANCES AND PERSPECTIVES. Journal of Liquid Chromatography & Related Technologies 25:8, pages 1153-1170.
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Wei-Lung Tseng, Tai-Chia Chiu, Jang-Mao Weng & Huan-Tsung Chang. (2001) ANALYSIS OF ALBUMINS, USING ALBUMIN BLUE 580, BY CAPILLARY ELECTROPHORESIS AND LASER-INDUCED FLUORESCENCE. Journal of Liquid Chromatography & Related Technologies 24:19, pages 2971-2982.
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Z. Yang & S.C. Beale. (1998) Investigation of Chemical Modification of Peptide Amine Groups for Compatibility with Fluorescent Labeling and Capillary Electrophoresis. Journal of Liquid Chromatography & Related Technologies 21:11, pages 1591-1611.
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Articles from other publishers (49)

François Couderc, Varravaddheay Ong-Meang & Véréna Poinsot. (2017) Capillary electrophoresis hyphenated with UV-native-laser induced fluorescence detection (CE/UV-native-LIF). ELECTROPHORESIS 38:1, pages 135-149.
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Bregje J. de Kort, Gerhardus J. de Jong & Govert W. Somsen. (2013) Native fluorescence detection of biomolecular and pharmaceutical compounds in capillary electrophoresis: Detector designs, performance and applications: A review. Analytica Chimica Acta 766, pages 13-33.
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Qian Tao, Ming-Xia Gao, Guang-Feng Hong, Qi Chen & Xiang-Min Zhang. (2011) Solid-support fluorescent derivatization of picomoles of protein at low concentration with FITC. Talanta 84:2, pages 457-461.
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King C. Chan, Timothy D. Veenstra & Haleem J. Issaq. (2011) Comparison of Fluorescence, Laser-Induced Fluorescence, and Ultraviolet Absorbance Detection for Measuring HPLC Fractionated Protein/Peptide Mixtures. Analytical Chemistry 83:6, pages 2394-2396.
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Gamze Kavran Belin, Valeria Gärtner & Stefan Seeger. (2009) Rapid analysis and sensitive detection of dl-tryptophan by using shorter capillary column coupled with deep-UV fluorescence detector. Journal of Chromatography B 877:29, pages 3753-3756.
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Dragana Č. Radenović, Bregje J. de Kort & Govert W. Somsen. (2009) Lamp-based native fluorescence detection of proteins in capillary electrophoresis. Journal of Chromatography A 1216:21, pages 4629-4632.
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Haleem J. Issaq, King C. Chan, Josip Blonder, Xiaoying Ye & Timothy D. Veenstra. (2009) Separation, detection and quantitation of peptides by liquid chromatography and capillary electrochromatography. Journal of Chromatography A 1216:10, pages 1825-1837.
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Julie Schappler, Aline Staub, Jean-Luc Veuthey & Serge Rudaz. (2008) Highly sensitive detection of pharmaceutical compounds in biological fluids using capillary electrophoresis coupled with laser-induced native fluorescence. Journal of Chromatography A 1204:2, pages 183-190.
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Ana M. García-Campaña, Myriam Taverna & Huguette Fabre. (2007) LIF detection of peptides and proteins in CE. ELECTROPHORESIS 28:1-2, pages 208-232.
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Stanislas Krawczyk. (2003) Discussion on optical integration in Lab‐on‐a‐Chip microsystems for medical diagnostics. physica status solidi (c):3, pages 998-1012.
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Haleem J Issaq. 2003. Proteome Characterization and Proteomics. Proteome Characterization and Proteomics 249 269 .
Haleem J. Issaq. (2001) The role of separation science in proteomics research. ELECTROPHORESIS 22:17, pages 3629-3638.
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Shaoxiang Xiong, Huiwan Han, Rui Zhao, Yi Chen & Guoquan Liu. (2001) Capillary electrophoresis of catecholamines with laser‐induced fluorescence intensified charge‐coupled device detection. Biomedical Chromatography 15:2, pages 83-88.
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King C. Chan, Gary M. Muschik & Haleem J. Issaq. (2000) Solid-state UV laser-induced fluorescence detection in capillary electrophoresis. Electrophoresis 21:10, pages 2062-2066.
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Haleem J. Issaq. (2000) A decade of capillary electrophoresis. Electrophoresis 21:10, pages 1921-1939.
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Climaco J. Metral, George M. Janini, Gary M. Muschik & Haleem J. Issaq. (1999) A Computer Method for Predicting the Electrophoretic Mobility of Peptides. Journal of High Resolution Chromatography 22:7, pages 373-378.
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Paula G. Coble & Aaron T. Timperman. (1998) Fluorescence detection of proteins and amino acids in capillary electrophoresis using a post-column sheath flow reactor. Journal of Chromatography A 829:1-2, pages 309-315.
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Hermann Wätzig, Matthias Degenhardt & Annette Kunkel. (1998) Strategies for capillary electrophoresis: Method development and validation for pharmaceutical and biological applications. Electrophoresis 19:16-17, pages 2695-2752.
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Donald M Paquette, Robert Sing, Peter R Banks & Karen C Waldron*. (1998) Capillary electrophoresis with laser-induced native fluorescence detection for profiling body fluids. Journal of Chromatography B: Biomedical Sciences and Applications 714:1, pages 47-57.
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Li Tao & Robert T Kennedy. (1998) Laser-induced fluorescence detection in microcolumn separations. TrAC Trends in Analytical Chemistry 17:8-9, pages 484-491.
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J. R. Veraart, S. J. Kok, J. M. te Koppele, C. Gooijer, H. Lingeman, N. H. Velthorst & U. A. Th. Brinkman. (1998) Capillary electrophoresis of the collagen crosslinks HP and LP utilizing absorbance, wavelength-resolved laser-induced fluorescence and conventional fluorescence detection. Biomedical Chromatography 12:4, pages 226-231.
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James A. Dickson, Matt M. Ferris & Robert E. Milofsky. (2005) Tris (2,2′‐bipyridyl)ruthenium (III) as a chemiluminescent reagent for detection in capillary electrophresis. Journal of High Resolution Chromatography 20:12, pages 643-646.
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Irene Messana, Diana Valeria Rossetti, Loredana Cassiano, Francesco Misiti, Bruno Giardina & Massimo Castagnola. (1997) Peptide analysis by capillary (zone) electrophoresis. Journal of Chromatography B: Biomedical Sciences and Applications 699:1-2, pages 149-171.
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Norberto A. Guzman, SungAe S. Park, Daniel Schaufelberger, Luis Hernandez, Ximena Paez, Pedro Rada, Andy J. Tomlinson & Stephen Naylor. (1997) New approaches in clinical chemistry: on-line analyte concentration and microreaction capillary electrophoresis for the determination of drugs, metabolic intermediates, and biopolymers in biological fluids. Journal of Chromatography B: Biomedical Sciences and Applications 697:1-2, pages 37-66.
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King C. Chan, Gary M. Muschik & Haleem J. Issaq. (1997) High-speed electrophoretic separation of DNA fragments using a short capillary. Journal of Chromatography B: Biomedical Sciences and Applications 695:1, pages 113-115.
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Steven J. Kok, E. Maria Kristenson, Cees Gooijer, Nel H. Velthorst & Udo A.Th. Brinkman. (1997) Wavelength-resolved laser-induced fluorescence detection in capillary electrophoresis: naphthalenesulphonates in river water. Journal of Chromatography A 771:1-2, pages 331-341.
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O. Stålberg, D. Westerlund, U-K. Hultin & S. Schmidt. (1997) Improvements in drug purity determination by capillary electrophoresis using UV-absorption and LIF-detection with a UV-laser. Chromatographia 44:7-8, pages 355-361.
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K. Kitagishi. 1997. Handbook of Capillary Electrophoresis Applications. Handbook of Capillary Electrophoresis Applications 84 103 .
Christine E. MacTaylor & Andrew G. Ewing. (1997) Critical review of recent developments in fluorescence detection for capillary electrophoresis. Electrophoresis 18:12-13, pages 2279-2290.
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Haleem J. Issaq, King C. Chan & Gary M. Muschik. (2005) The effect of column length, applied voltage, gel type, and concentration on the capillary electrophoresis separation of DNA fragments and polymerase chain reaction products. ELECTROPHORESIS 18:7, pages 1153-1158.
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Maria Nordén & Ewa Dabek‐Zlotorzynska. (2005) Characterization of humic substances using capillary electrophoresis with photodiode array and laser‐induced fluorescence detection. ELECTROPHORESIS 18:2, pages 292-299.
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R. Swart, J. W. Elgersma, J. C. Kraak & H. Poppe. (1997) Experiences with a frequency-doubled argon ion laser for fluorescence detection in open tubular liquid chromatography. Journal of Microcolumn Separations 9:8, pages 591-600.
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R. S. Ramsey & S. A. McLuckey. (1997) Charge concentration in electrospray ionization: Mass spectrometry for sensitive detection of proteins. Journal of Microcolumn Separations 9:7, pages 523-528.
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George M. Janini, Gary M. Muschik & Haleem J. Issaq. (1996) Micellar electrokinetic chromatography in zero-electroosmotic flow environment. Journal of Chromatography B: Biomedical Sciences and Applications 683:1, pages 29-35.
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Steven J. Kok, Emile H. M. Koster, Cees Gooijer, Nel H. Velthorst, Udo A. Th. Brinkman & Orfeo Zerbinati. (2005) Separation of twenty‐one naphthalene sulfonates by means of capillary electrophoresis. Journal of High Resolution Chromatography 19:2, pages 99-104.
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King C. Chan, Gary M. Muschik & Haleem J. Issaq. (1995) Separation of tryptophan and related indoles by micellar electrokinetic chromatography with KrF laser-induced fluorescence detection. Journal of Chromatography A 718:1, pages 203-210.
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Aaron T. Timperman, Kurt E. Oldenburg & Jonathan V. Sweedler. (2002) Native fluorescence detection and spectral differentiation of peptides containing tryptophan and tyrosine in capillary electrophoresis. Analytical Chemistry 67:19, pages 3421-3426.
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Ira S. Lurie, King C. Chan, Trinette K. Spratley, John F. Casale & Haleem J. Issaq. (1995) Separation and detection of acidic and neutral impurities in illicit heroin via capillary electrophoresis. Journal of Chromatography B: Biomedical Sciences and Applications 669:1, pages 3-13.
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Frederic. Robert, Lionel. Bert, Luc. Denoroy & Bernard. Renaud. (2002) Capillary zone electrophoresis with laser-induced fluorescence detection for the determination of nanomolar concentrations of noradrenaline and dopamine: application to brain microdialyzate analysis. Analytical Chemistry 67:11, pages 1838-1844.
Crossref
R.J. van de Nesse, N.H. Velthorst, U.A.Th. Brinkman & C. Gooijer. (1995) Laser-induced fluorescence detection of native-fluorescent analytes in column liquid chromatography, a critical evaluation. Journal of Chromatography A 704:1, pages 1-25.
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JoséMaría Saz, Beat Krattiger, Alfredo E. Bruno, JoséCarlos Díez-Masa & H.Michael Widmer. (1995) Thermo-optical absorbance detection of native proteins separated by capillary electrophoresis in 10 μm I.D. tubes. Journal of Chromatography A 699:1-2, pages 315-322.
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Devanand M. Pinto, Edgar A. Arriaga, Samuel Sia, Zhong Li & Norman J. Dovichi. (2005) Solid‐phase fluorescent labeling reaction of picomole amounts of insulin in very dilute solutions and their analysis by capillary electrophoresis. ELECTROPHORESIS 16:1, pages 534-540.
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King C. Chan, Gary M. Muschik & Haleem J. Issaq. (2005) Enantiomeric separation of amino acids using micellar electrokinetic chromatography after pre‐column derivatization with the chiral reagent 1‐(9‐fluorenyl)‐ethyl chloroformate. ELECTROPHORESIS 16:1, pages 504-509.
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Haleem J. Issaq & King C. Chan. (2005) Separation and detection of amino acids and their enantiomers by capillary electrophoresis: A review. ELECTROPHORESIS 16:1, pages 467-480.
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Jonas. Bergquist, S. Douglass. Gilman, Andrew G. Ewing & Rolf. Ekman. (2002) Analysis of Human Cerebrospinal Fluid by Capillary Electrophoresis with Laser-Induced Fluorescence Detection. Analytical Chemistry 66:20, pages 3512-3518.
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Curtis A. Monnig & Robert T. Kennedy. (2002) Capillary Electrophoresis. Analytical Chemistry 66:12, pages 280-314.
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King C. Chan, George M. Janini, Gary M. Muschik & Haleem J. Issaq. (1993) Micellar electrokinetic chromatography of hydroxyproline and other secondary amino acids in biological samples with laser-induced fluorescence detection. Journal of Chromatography B: Biomedical Sciences and Applications 622:2, pages 269-273.
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George M. Janini, King C. Chan, Jeffrey A. Barnes, Gary M. Muschik & Haleem J. Issaq. (1993) Separation of pyridinecarboxylic acid isomers and related compounds by capillary zone electrophoresis. Journal of Chromatography A 653:2, pages 321-327.
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King C. Chan, George M. Janini, Gary M. Muschik & Haleem J. Issaq. (1993) Laser-induced fluorescence detection of 9-fluorenylmethyl chloroformate derivatized amino acids in capillary electrophoresis. Journal of Chromatography A 653:1, pages 93-97.
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