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Journal of Liquid Chromatography Volume 16, 1993 - Issue 4
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Original Articles

Chiral Separation of Lorazepam on Ovomucoid-Bonded Columns: Peak Coalescence Due to Racemization

H. Fujima IShinwa Chemical Industries, Ltd., 50 Kagekatsu-cho Fushimi-ku, Kyoto, 612, Japan
,
H. Wada IShinwa Chemical Industries, Ltd., 50 Kagekatsu-cho Fushimi-ku, Kyoto, 612, Japan
,
T. Miwa Eisai Co., Ltd. Pharmaceutical Research Laboratory, 2-1 Takehaya-machi, Kawashima-cho Hashima-gun, Gifu, 483, Japan
&
J. Haginaka Faculty of Pharmaceutical Sciences Mukogawa Women's University, 11-68, Koshien Kyuban-cho Nishinomiya, Hyogo, 663, Japan
Pages 879-891 | Published online: 23 Sep 2006

Citations (13)

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Guy Felix & Alain Berthod. (2008) Part II: From Dermatologicals to Sensory Organ and Various Drugs. Separation & Purification Reviews 37:1-2, pages 1-227.
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Thomas A. Walker. (2000) THE CHIRAL SEPARATION OF OXYBUTYNIN ENANTIOMERS USING AN OVOMUCOID COLUMN. Journal of Liquid Chromatography & Related Technologies 23:6, pages 841-853.
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Chun-Sheng Chang & Shau-Wei Tsai. (1998) Enantioselective Adsorption of (+)-(S)-Naproxen in a Crosslinked Lipase in Organic Solvents. Separation Science and Technology 33:14, pages 2113-2122.
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Mu-Bing Huang, Gao-Lan Li, Guo-Sheng Yang, Yu-Hao Shi, Jian-Jun Gao & Xiang-De Liu. (1997) Enantiomeric Separation of Aromatic Amino Alcohol Drugs By Chiral Ion-Pair Chromatography On A Silica Gel Plate. Journal of Liquid Chromatography & Related Technologies 20:10, pages 1507-1514.
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Articles from other publishers (9)

Eva Tesařová & Zuzana Bosáková. (2003) Comparison of enantioseparation of selected benzodiazepine and phenothiazine derivatives on chiral stationary phases based on β‐cyclodextrin and macrocyclic antibiotics. Journal of Separation Science 26:8, pages 661-668.
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James S. Munro & Thomas A. Walker. (2001) Bupropion hydrochloride: the development of a chiral separation using an ovomucoid column. Journal of Chromatography A 913:1-2, pages 275-282.
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Keith J. Duff. 2007. Encyclopedia of Analytical Chemistry. Encyclopedia of Analytical Chemistry.
Amir Avdagić, Andreja Lesac, Zsuzsa Majer, Miklòs Hollòsi & Vitomir Šunjić. (1998) Lipase-Catalyzed Acetylation of 3-Substituted 2,3-Dihydro-1 H -1,4-benzodiazepin-2-ones: Effect of temperature and conformation on enantioselectivity and configuration . Helvetica Chimica Acta 81:5-8, pages 1567-1582.
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Heike Hofstetter, Oliver Hofstetter & Volker Schurig. (1998) Enantiomer separation using BSA as chiral stationary phase in affinity OTEC and OTLC. Journal of Microcolumn Separations 10:3, pages 287-291.
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Takashi Nishikawa, Yoshinori Hayashi, Satomi Suzuki, Hiroaki Kubo & Hideki Ohtani. (1997) On-column enantiomerization of 3-hydroxybenzodiazepines during chiral liquid chromatography with optical rotation detection. Journal of Chromatography A 767:1-2, pages 93-100.
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Julie Ducharme, Christine Fernandez, François Gimenez & Robert Farinotti. (1996) Critical issues in chiral drug analysis in biological fluids by high-performance liquid chromatography. Journal of Chromatography B: Biomedical Sciences and Applications 686:1, pages 65-75.
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S. Boonkerd, M.R. Detaevernier, Y. Michotte & J. Vindevogel. (1995) Suppression of chiral recognition of 3-hydroxy-1,4-benzodiazepines during micellar electrokinetic capillary chromatography with bile salts. Journal of Chromatography A 704:1, pages 238-241.
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Karin Cabrera & Dieter Lubda. (1994) Influence of temperature on chiral high-performance liquid chromatographic separations of oxazepam and Prominal on chemically bonded β-cyclodextrin as stationary phase. Journal of Chromatography A 666:1-2, pages 433-438.
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