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Original Articles

Extraction Procedures for the HPLC Determination of 5-Fluorouracil in Biological Samples

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Pages 1621-1636 | Received 09 Oct 1993, Accepted 19 Oct 1993, Published online: 23 Sep 2006

Keep up to date with the latest research on this topic with citation updates for this article.

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Ning Wang, Ting Wang, Maoling Wang, Aijun Hao & Tiefu Li. (2011) USING ULTRAFILTRATION TO FACILITATE SIMULTANEOUS QUANTIFICATION OF 5-FLUOROURACIL IN MOUSE PLASMA AND TISSUES BY HPLC. Journal of Liquid Chromatography & Related Technologies 34:18, pages 2033-2047.
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MushtaqA. Fruitwala & N.M. Sanghavi. (1997) HPLC Analysis and Validation of 5-Fluorouracil and Its Metabolites in Rat Plasma. Journal of Liquid Chromatography & Related Technologies 20:3, pages 471-480.
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Articles from other publishers (7)

Petros Mavromatis, Kyriaki Stampouli, Angeliki Vliora, Anna Mayilyan, Victoria Samanidou & Maria Touraki. (2022) Development of an HPLC-DAD Method for the Extraction and Quantification of 5-Fluorouracil, Uracil, and 5-Fluorodeoxyuridin Monophosphate in Cells and Culture Media of Lactococcus lactis. Separations 9:11, pages 376.
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Maryam Nazemian, Vida Hojati, Saeed Zavareh, Hamid Madanchi & Hamid Hashemi-Moghaddam. (2019) Immobilized Peptide on the Surface of Poly l-DOPA/Silica for Targeted Delivery of 5-Fluorouracil to Breast Tumor. International Journal of Peptide Research and Therapeutics 26:1, pages 259-269.
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Hamid Hashemi-Moghaddam, Saeed Zavareh, Elnaz Mirsaeed Gazi & Mahdi Jamili. (2018) Assessment of novel core–shell Fe3O4@poly l‑DOPA nanoparticles for targeted Taxol® delivery to breast tumor in a mouse model. Materials Science and Engineering: C 93, pages 1036-1043.
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Hamid Hashemi-Moghaddam, Saeed Kazemi-Bagsangani, Mahdi Jamili & Saeed Zavareh. (2016) Evaluation of magnetic nanoparticles coated by 5-fluorouracil imprinted polymer for controlled drug delivery in mouse breast cancer model. International Journal of Pharmaceutics 497:1-2, pages 228-238.
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D. V. Moiseev, S. I. Marchenko, A. M. Moiseeva, T. V. Trukhacheva, P. T. Petrov & A. I. Zhebentyaev. (2007) HPLC in biopharmaceutical investigations of drugs representing pyrimidine derivatives (A review). Pharmaceutical Chemistry Journal 41:1, pages 25-33.
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F. Casale, R. Canaparo, E. Muntoni, L. Serpe, G.P. Zara, C. Della Pepa, E. Berno, M. Costa & M. Eandi. (2002) Simultaneous HPLC determination of 5‐fluorouracil and its metabolites in plasma of cancer patients. Biomedical Chromatography 16:7, pages 446-452.
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M.J. Del Nozal, J.L. Bernal, A. Pampliega, P. Marinero & M. Pozuelo. (1994) Determination of the concentrations of 5-fluorouracil and its metabolites in rabbit plasma and tissues by high-performance liquid chromatography. Journal of Chromatography B: Biomedical Sciences and Applications 656:2, pages 397-405.
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