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Journal of Liquid Chromatography Volume 18, 1995 - Issue 18-19: Capillary Zone Electrophoresis and Related Techniques
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Original Articles

Biomedical Applications of On-Line Preconcentration-Capillary Electrophoresis Using an Analyte Concentrator: Investigation of Design Options

Norberto A. Guzman Protein Research Unit, Princeton Biochemicals, Inc., Princeton, New Jersey, 08543; The R.W. Johnson Pharmaceutical Research Institute, a Johnson & Johnson company, Raritan, New Jersey, 08869, U.S.A.
Pages 3751-3768 | Received 18 Aug 1995, Accepted 06 Sep 1995, Published online: 23 Sep 2006

Citations (45)

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Mitchell E. Johnson & Tara S. Carpenter. (2005) The Use of Solid‐Phase Supports for Derivatization in Chromatography and Spectroscopy. Applied Spectroscopy Reviews 40:4, pages 391-412.
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William Clarke & David S. Hage. (2003) Clinical Applications of Affinity Chromatography . Separation & Purification Reviews 32:1, pages 19-60.
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Articles from other publishers (43)

Norberto A. Guzman, Daniel E. Guzman & Timothy Blanc. (2023) Advancements in Portable Instruments Based on Affinity-Capture-Migration and Affinity-Capture-Separation for Use in Clinical Testing and Life Science Applications.. Journal of Chromatography A, pages 464109.
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Kiyohito Shimura & Toshihiko Nagai. (2016) Capillary isoelectric focusing after sample enrichment with immunoaffinity chromatography in a single capillary. Scientific Reports 6:1.
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Norberto A. Guzman & Daniel E. Guzman. (2016) An emerging micro-scale immuno-analytical diagnostic tool to see the unseen. Holding promise for precision medicine and P4 medicine. Journal of Chromatography B 1021, pages 14-29.
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Zhenbin Zhang, Liangliang Sun, Guijie Zhu, Xiaojing Yan & Norman J. Dovichi. (2015) Integrated strong cation-exchange hybrid monolith coupled with capillary zone electrophoresis and simultaneous dynamic pH junction for large-volume proteomic analysis by mass spectrometry. Talanta 138, pages 117-122.
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Kiyohito Shimura & Toshihiko Nagai. (2015) Direct coupling of immobilized metal ion affinity chromatography and capillary isoelectric focusing in a single capillary. Journal of Electrophoresis 59:1, pages 7-17.
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David S. Hage. 2007. Encyclopedia of Analytical Chemistry. Encyclopedia of Analytical Chemistry.
Michael C. Breadmore, Mohamed Dawod & Joselito P. Quirino. (2011) Recent advances in enhancing the sensitivity of electrophoresis and electrochromatography in capillaries and microchips (2008-2010). ELECTROPHORESIS 32:1, pages 127-148.
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Nora Vizioli, Raúl Gil, Luis Dante Martínez & María Fernanda Silva. (2009) On-line solid phase extraction CZE for the simultaneous determination of lanthanum and gadolinium at picogram per liter levels. ELECTROPHORESIS 30:15, pages 2681-2687.
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Hong-Xu Chen, Jean-Marc Busnel, Gabriel Peltre, Xin-Xiang Zhang & Hubert H. Girault. (2008) Magnetic Beads Based Immunoaffinity Capillary Electrophoresis of Total Serum IgE with Laser-Induced Fluorescence Detection. Analytical Chemistry 80:24, pages 9583-9588.
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Patcharin Chaisuwan, Duangjai Nacapricha, Prapin Wilairat, Zhengjin Jiang & Norman William Smith. (2008) Monolithic and packed particle materials for in-line pre-concentration in capillary electrophoresis for 4-hydroxy-3-methoxy-methamphetamine and terbutaline. ELECTROPHORESIS 29:19, pages 4008-4016.
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Norberto A. Guzman, Timothy Blanc & Terry M. Phillips. (2008) Immunoaffinity capillary electrophoresis as a powerful strategy for the quantification of low-abundance biomarkers, drugs, and metabolites in biological matrices. ELECTROPHORESIS 29:16, pages 3259-3278.
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F. W. Alexander Tempels, Willy J. M. Underberg, Govert W. Somsen & Gerhardus J. de Jong. (2008) Design and applications of coupled SPE-CE. ELECTROPHORESIS 29:1, pages 108-128.
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Fernando Benavente, M. Cristina Vescina, Elena Hernández, Victoria Sanz-Nebot, José Barbosa & Norberto A. Guzman. (2007) Lowering the concentration limits of detection by on-line solid-phase extraction–capillary electrophoresis–electrospray mass spectrometry. Journal of Chromatography A 1140:1-2, pages 205-212.
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Michael C. Breadmore. (2007) Recent advances in enhancing the sensitivity of electrophoresis and electrochromatography in capillaries and microchips. ELECTROPHORESIS 28:1-2, pages 254-281.
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Jenny M. Armenta, Binghe Gu, Paul H. Humble, Craig D. Thulin & Milton L. Lee. (2005) Design and evaluation of a coupled monolithic preconcentrator-capillary zone electrophoresis system for the extraction of immunoglobulin G from human serum. Journal of Chromatography A 1097:1-2, pages 171-178.
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Nora M. Vizioli, Maria Lucía Rusell, Maria Laura Carbajal, Clyde N. Carducci & Mariano Grasselli. (2005) On-line affinity selection of histidine-containing peptides using a polymeric monolithic support for capillary electrophoresis. ELECTROPHORESIS 26:15, pages 2942-2948.
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F TEMPELS, J TEEUWSEN, I KYRIAKOU, G THEODORIDIS, W UNDERBERG, G SOMSEN & G DEJONG. (2004) Chromatographic preconcentration coupled on-line to capillary electrophoresis via a Tee-split interface. Journal of Chromatography A 1053:1-2, pages 263-268.
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F. W. Alexander Tempels, Willy J. M. Underberg, Govert W. Somsen & Gerhardus J. de Jong. (2004) Chromatographic Preconcentration Coupled To Capillary Electrophoresis via an In-Line Injection Valve. Analytical Chemistry 76:15, pages 4432-4436.
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William Clarke & David Hage. 2003. Separation Techniques in Clinical Chemistry. Separation Techniques in Clinical Chemistry.
William Clarke & David Hage. 2003. Separation Techniques in Clinical Chemistry. Separation Techniques in Clinical Chemistry.
Sònia Sentellas, Lluís Puignou & M. Teresa Galceran. (2002) Capillary electrophoresis with on-line enrichment for the analysis of biological samples. Journal of Separation Science 25:15-17, pages 975-987.
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Norberto A. Guzman & R. John Stubbs. (2001) The use of selective adsorbents in capillary electrophoresis-mass spectrometry for analyte preconcentration and microreactions: A powerful three-dimensional tool for multiple chemical and biological applications. ELECTROPHORESIS 22:17, pages 3602-3628.
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Miguel Valcárcel, Lourdes Arce & Angel Rı́os. (2001) Coupling continuous separation techniques to capillary electrophoresis. Journal of Chromatography A 924:1-2, pages 3-30.
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Michael C. Breadmore & Paul R. Haddad. (2001) Approaches to enhancing the sensitivity of capillary electrophoresis methods for the determination of inorganic and small organic anions. ELECTROPHORESIS 22:12, pages 2464-2489.
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Michael C. Breadmore, Miroslav Macka, Nebojsa Avdalovic & Paul R. Haddad. (2001) On-Capillary Ion-Exchange Preconcentration of Inorganic Anions in Open-Tubular Capillary Electrochromatography with Elution Using Transient-Isotachophoretic Gradients. 2. Characterization of the Isotachophoretic Gradient. Analytical Chemistry 73:4, pages 820-828.
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James S Fritz & Miroslav Macka. (2000) Solid-phase trapping of solutes for further chromatographic or electrophoretic analysis. Journal of Chromatography A 902:1, pages 137-166.
Crossref
David S. Hage. 2007. Encyclopedia of Analytical Chemistry. Encyclopedia of Analytical Chemistry.
Andy J. Tomlinson & Stephen Naylor. 2007. Encyclopedia of Analytical Chemistry. Encyclopedia of Analytical Chemistry.
Joop C. M. Waterval, Gerald Hommels, Jan Teeuwsen, Auke Bult, Henk Lingeman & Willy J. M. Underberg. (2000) Quantitative analysis of pharmaceutically active peptides using on-capillary analyte preconcentration transient isotachophoresis. Electrophoresis 21:14, pages 2851-2858.
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Norberto A Guzman. (2000) Determination of immunoreactive gonadotropin-releasing hormone in serum and urine by on-line immunoaffinity capillary electrophoresis coupled to mass spectrometry. Journal of Chromatography B: Biomedical Sciences and Applications 749:2, pages 197-213.
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David S Hage. (1999) Affinity Chromatography: A Review of Clinical Applications. Clinical Chemistry 45:5, pages 593-615.
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Joseph J. Dalluge & Lane C. Sander. (1998) Precolumn Affinity Capillary Electrophoresis for the Identification of Clinically Relevant Proteins in Human Serum:  Application to Human Cardiac Troponin I. Analytical Chemistry 70:24, pages 5339-5343.
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Niels H.H Heegaard, Staffan Nilsson & Norberto A Guzman. (1998) Affinity capillary electrophoresis: important application areas and some recent developments. Journal of Chromatography B: Biomedical Sciences and Applications 715:1, pages 29-54.
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David S. Hage. (1998) Survey of recent advances in analytical applications of immunoaffinity chromatography. Journal of Chromatography B: Biomedical Sciences and Applications 715:1, pages 3-28.
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Stephen C. Beale. (1998) Capillary Electrophoresis. Analytical Chemistry 70:12, pages 279-300.
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Qing YANG, Andy J. TOMLINSON & Stephen NAYLOR. 1998. Advanced Chromatographic and Electromigration Methods in BioSciences. Advanced Chromatographic and Electromigration Methods in BioSciences 95 140 .
Carsten B Knudsen & John H Beattie. (1997) On-line solid-phase extraction–capillary electrophoresis for enhanced detection sensitivity and selectivity: application to the analysis of metallothionein isoforms in sheep fetal liver. Journal of Chromatography A 792:1-2, pages 463-473.
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Norberto A. Guzman, SungAe S. Park, Daniel Schaufelberger, Luis Hernandez, Ximena Paez, Pedro Rada, Andy J. Tomlinson & Stephen Naylor. (1997) New approaches in clinical chemistry: on-line analyte concentration and microreaction capillary electrophoresis for the determination of drugs, metabolic intermediates, and biopolymers in biological fluids. Journal of Chromatography B: Biomedical Sciences and Applications 697:1-2, pages 37-66.
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David J. Anderson, Baochuan Guo, Yan Xu, Lily M. Ng, Larry J. Kricka, Kristen J. Skogerboe, David S. Hage, Larry Schoeff, Joseph Wang, Lori J. Sokoll, Daniel W. Chan, Kory M. Ward & Katherine A. Davis. (1997) Clinical Chemistry. Analytical Chemistry 69:12, pages 165-230.
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Rong Zhang & Stellan Hjertén. (1997) A Micromethod for Concentration and Desalting Utilizing a Hollow Fiber, with Special Reference to Capillary Electrophoresis. Analytical Chemistry 69:8, pages 1585-1592.
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Andy J. Tomlinson, Linda M. Benson, Norberto A. Guzman & Stephen Naylor. 1997. 15 24 .
Geza Rippel, Hugo Corstjens, Hugo A. H. Billiet & Johannes Frank. (1997) Affinity capillary electrophoresis. Electrophoresis 18:12-13, pages 2175-2183.
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Andy J. Tomlinson, Linda M. Benson, Norberto A. Guzman & Stephen Naylor. (1996) Preconcentration and microreaction technology on-line with capillary electrophoresis. Journal of Chromatography A 744:1-2, pages 3-15.
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