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Original Articles

High Performance Liquid Chromatographic Determination of Tramadol in Pharmaceutical Dosage Forms

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Pages 779-787 | Received 13 May 1996, Accepted 05 Jun 1996, Published online: 23 Sep 2006

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Fu-chao Chen, Jun Zhu, Bin Li, Fang-jun Yuan & Lin-hai Wang. (2016) Stability of tramadol with three 5-HT3 receptor antagonists in polyolefin bags for patient-controlled delivery systems. Drug Design, Development and Therapy 10, pages 1869-1875.
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Articles from other publishers (18)

Mehrnoosh Sadeghi, Mehdi Shabani-Nooshabadi & Hanieh Ansarinejad. (2023) A nanoporous gold film sensor modified with polypyrrole/CuO nanocomposite for electrochemical determination of piroxicam and tramadole. Environmental Research 216, pages 114633.
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U. A. Murashova, L. V. Skalkina, P. V. Kazakov & N. S. Mirzabekova. (2020) Development of Chromatographic Methods for Assay of Contaminants of Russian-Made Tramadol Hydrochloride Substance. Pharmaceutical Chemistry Journal 54:7, pages 766-771.
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Malihe Samadi Kazemi. (2015) Determination of tramadol hydrochloride in water samples by directly suspended droplet three-phase liquid phase microextraction with tetrathiocyanato cobalt(II) as the complexing agent using UV-spectroscopy. Journal of Analytical Chemistry 70:11, pages 1330-1335.
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Ziya Bayrak, Sevinc Kurbanoglu, Ayhan Savaser, Sibel A. Ozkan, Hikmet Altunay, Cetin Tas, Cansel Kose Ozkan & Yalcin Ozkan. (2013) LC–MS Method for the Sensitive Determination of Metoclopramide: Application to Rabbit Plasma, Gel Formulations and Pharmaceuticals. Chromatographia 77:1-2, pages 99-107.
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Robert Smyj, Xiao-Ping Wang & Feixue Han. 2013. Profiles of Drug Substances, Excipients, and Related Methodology. Profiles of Drug Substances, Excipients, and Related Methodology 463 494 .
Kanakapura B. Vinay, Hosakere D. Revannasiddappa, Nagaraju Rajendraprasad, Pavagada J. Ramesh, Cijo M. Xavier & Kanakapura Basavaiah. (2012) Use of two sulfonthalein dyes in the extraction-free spectrophotometric assay of tramadol in dosage forms and in spiked human urine based on ion-pair reaction. Drug Testing and Analysis 4:2, pages 116-122.
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Kanakapura B. Vinay, Hosakere D. Revanasiddappa, Cijo M. Xavier, Pavagada J. Ramesh & Madihalli S. Raghu. (2012) A Stability Indicating UPLC Method for the Determination of Tramadol Hydrochloride: Application to Pharmaceutical Analysis. Chromatography Research International 2012, pages 1-9.
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Sofia NegroAlicia MartínLuz AzuaraYolanda SánchezEmilia Barcia. (2010) Compatibility and Stability of Ternary Admixtures of Tramadol, Haloperidol, and Hyoscine N -Butyl Bromide: Retrospective Clinical Evaluation . Journal of Palliative Medicine 13:3, pages 273-277.
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Pankaj K. Kachhadia, Ashish S. Doshi, Vijay R. Ram & Hitendra S. Joshi. (2008) Validated LC Method for Simultaneous Analysis of Tramadol Hydrochloride and Aceclofenac in a Commercial Tablet. Chromatographia 68:11-12, pages 997-1001.
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Emilia Barcia, Alicia Martín, María Luz Azuara, Yolanda Sánchez & Sofia Negro. (2006) Tramadol and hyoscine N-butyl bromide combined in infusion solutions: compatibility and stability. Supportive Care in Cancer 15:1, pages 57-62.
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Sofía Negro, Alicia Martín, María Luz Azuara, Yolanda Sánchez & Emilia Barcia. (2005) Stability of Tramadol and Haloperidol for Continuous Subcutaneous Infusion at Home. Journal of Pain and Symptom Management 30:2, pages 192-199.
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Norah O. Abanmy, Iman Y. Zaghloul & Mahasen A. Radwan. (2005) Compatibility of tramadol hydrochloride injection with selected drugs and solutions. American Journal of Health-System Pharmacy 62:12, pages 1299-1302.
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Aysel K???k, Y?cel Kad?o?lu & Fikret ?elebi. (2005) Investigation of the pharmacokinetics and determination of tramadol in rabbit plasma by a high-performance liquid chromatography?diode array detector method using liquid?liquid extraction. Journal of Chromatography B 816:1-2, pages 203-208.
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Aysel K???k & Y?cel Kad?o?lu. (2005) Determination of tramadol hydrochloride in ampoule dosage forms by using UV spectrophotometric and HPLC-DAD methods in methanol and water media. Il Farmaco 60:2, pages 163-169.
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E.M.P.J Garrido, J.M.P.J Garrido, F Borges & C Delerue-Matos. (2003) Development of electrochemical methods for determination of tramadol?analytical application to pharmaceutical dosage forms. Journal of Pharmaceutical and Biomedical Analysis 32:4-5, pages 975-981.
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Hisham E Abdellatef. (2002) Kinetic spectrophotometric determination of tramadol hydrochloride in pharmaceutical formulation. Journal of Pharmaceutical and Biomedical Analysis 29:5, pages 835-842.
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R. K. Gilpin & L. A. Pachla. (1999) Pharmaceuticals and Related Drugs. Analytical Chemistry 71:12, pages 217-234.
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M Posp???ilov?M Pol??ek & V Jokl. (1998) Determination of tramadol in various dosage forms by capillary isotachophoresis. Journal of Pharmaceutical and Biomedical Analysis 18:4-5, pages 777-783.
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