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Journal of Liquid Chromatography & Related Technologies Volume 21, 1998 - Issue 8
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Original Articles

Enantiomeric Resolution of Propranolol and Analogs on Two Cellulose (Chiralcel of and OC) AND One Amylose (Chiralpak Ad) Chiral Stationary Phases

H. Y. Aboul-Enein Bioanalytical and Drug Development Laboratory Biological and Medical Research Department, MBC-03 King Faisal Specialist Hospital & Research Centre, P.O. Box 3354, Riyadh, 11211, Saudi Arabia
&
S. A. Bakr Bioanalytical and Drug Development Laboratory Biological and Medical Research Department, MBC-03 King Faisal Specialist Hospital & Research Centre, P.O. Box 3354, Riyadh, 11211, Saudi Arabia
Pages 1137-1145 | Received 26 Sep 1997, Accepted 10 Oct 1997, Published online: 16 Aug 2006

Citations (24)

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Read on this site (4)

Guy Felix & Alain Berthod. (2007) Commercial Chiral Stationary Phases for the Separations of Clinical Racemic Drugs. Separation & Purification Reviews 36:4, pages 285-481.
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Martin G. Schmid, Orsolya Gecse, Zoltan Szabo, Ferenc Kilár, Gerald Gübitz, Imran Ali & Hassan Y. Aboul-Enein. (2001) COMPARATIVE STUDY OF THE CHIRAL RESOLUTION OF β-BLOCKERS ON CELLULOSE TRIS (3,5-DIMETHYL-PHENYLCARBAMATE) PHASES IN NORMAL AND REVERSED PHASE MODES. Journal of Liquid Chromatography & Related Technologies 24:16, pages 2493-2504.
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K. Hroboňová, J. Lehotay, R. Čižmáriková & D. W. Armstrong. (2001) STUDY OF THE MECHANISM OF ENANTIOSEPARATION. I. CHIRAL ANALYSIS OF ALKYLAMINO DERIVATIVES OF ARYLOXYPROPANOLS BY HPLC USING MACROCYCLIC ANTIBIOTICS AS CHIRAL SELECTORS. Journal of Liquid Chromatography & Related Technologies 24:15, pages 2225-2237.
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Marcelo M. Britto, Quezia B. Cass, Carlos A. I. Montanari & Hassan Y. Aboul-Enein. (1999) DETERMINATION OF PARTITION COEFFICIENTS FOR SEVERAL PROPRANOLOL ANALOGUES BY REVERSED PHASE HIGH PERFORMANCE LIQUID CHROMATOGRAPHY. Journal of Liquid Chromatography & Related Technologies 22:14, pages 2139-2149.
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Articles from other publishers (20)

Meng Li, Zhen Jiang, Xin Di & Yongbo Song. (2020) Enantiomeric separation of six beta‐adrenergic blockers on Chiralpak IB column and identification of chiral recognition mechanisms by molecular docking technique. Biomedical Chromatography 34:5.
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Andreea Bodoki, Bogdan-Cezar Iacob, Laura Gliga, Simona Oprean, David Spivak, Nicholas Gariano & Ede Bodoki. (2018) Improved Enantioselectivity for Atenolol Employing Pivot Based Molecular Imprinting. Molecules 23:8, pages 1875.
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Poonam Malik & Ravi Bhushan. (2018) Thin Layer Chromatographic Resolution of Some β-adrenolytics and a β2-Agonist Using Bovine Serum Albumin as Chiral Additive in Stationary Phase. Journal of Chromatographic Science 56:1, pages 92-98.
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Deepak Pathania, Mamta Kumari & Vinod Kumar Gupta. (2015) Fabrication of ZnS–cellulose nanocomposite for drug delivery, antibacterial and photocatalytic activity. Materials & Design 87, pages 1056-1064.
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Khalil FarhadiMehdi Hatami, Mehrdad Forough & Rahim Molaei. (2013) Dispersive liquid–liquid microextraction of propranolol enantiomers from human plasma based on the solidification of a floating organic droplet. Bioanalysis 5:6, pages 701-710.
Crossref
R. Čižmáriková, S. Chudáčiková, J. Valentová & A. Némethy. (2012) Synthesis and enantioseparation of derivatives of propranolol. Acta Facultatis Pharmaceuticae Universitatis Comenianae 59:1, pages 5-13.
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Sami El Deeb, Phillip Hasemann & Hermann Wätzig. (2008) Strategies in method development to quantify enantiomeric impurities using CE. ELECTROPHORESIS 29:17, pages 3552-3562.
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Ayşegül Gölcü. (2008) New, simple, and validated UV-spectrophotometric method for the estimation of some beta blockers in bulk and formulations. Journal of Analytical Chemistry 63:6, pages 538-543.
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N Matthijs, C Perrin, M Maftouh, D.L Massart & Y Vander Heyden. (2004) Definition and system implementation of strategies for method development of chiral separations in normal- or reversed-phase liquid chromatography using polysaccharide-based stationary phases. Journal of Chromatography A 1041:1-2, pages 119-133.
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Ali A El-Emam, Fathalla F Belal, Mohamed A Moustafa, Saadia M El-Ashry, Dina T El-Sherbiny & Steen Honoré Hansen. (2003) Spectrophotometric determination of propranolol in formulations via oxidative coupling with 3-methylbenzothiazoline-2-one hydrazone. Il Farmaco 58:11, pages 1179-1186.
Crossref
Hassan Aboul-Enein & Imran Ali. 2003. Chiral Separations By Liquid Chromatography And Related Technologies. Chiral Separations By Liquid Chromatography And Related Technologies 21 88 .
Jacek Bojarski. (2002) Stereoselective chromatography of cardiovascular drugs: an update. Journal of Biochemical and Biophysical Methods 54:1-3, pages 197-220.
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N Matthijs, C Perrin, M Maftouh, D.L Massart & Y Vander Heyden. (2002) Knowledge-based system for method development of chiral separations with capillary electrophoresis using highly-sulphated cyclodextrins. Journal of Pharmaceutical and Biomedical Analysis 27:3-4, pages 515-529.
Crossref
L Toribio, J.L Bernal, M.J del Nozal, J.J Jiménez & E.M Nieto. (2001) Applications of the Chiralpak AD and Chiralcel OD chiral columns in the enantiomeric separation of several dioxolane compounds by supercritical fluid chromatography. Journal of Chromatography A 921:2, pages 305-313.
Crossref
M.A. El-Ries, F.M. Abou Attia & S.A. Ibrahim. (2000) AAS and spectrophotometric determination of propranolol HCl and metoprolol tartrate. Journal of Pharmaceutical and Biomedical Analysis 24:2, pages 179-187.
Crossref
H. Y. Aboul-Enein & I. Ali. (2000) Macrocyclic antibiotics as effective chiral selectors for enantiomeric resolution by liquid chromatography and capillary electrophoresis. Chromatographia 52:11-12, pages 679-691.
Crossref
J.L Bernal, M.J del Nozal, L Toribio, M.I Montequi & E.M Nieto. (2000) Separation of ketoconazole enantiomers by chiral subcritical-fluid chromatography. Journal of Biochemical and Biophysical Methods 43:1-3, pages 241-250.
Crossref
Xiaoxia Bai, Tianyan You, Hanwen Sun, Xiurong Yang & Erkang Wang. (2000) Determination of Propranolol by Capillary Electrophoresis with End-Column Amperometric Detection. Electroanalysis 12:7, pages 535-537.
Crossref
J.L. Bernal, L. Toribio, M.J. del Nozal, E.M. Nieto & J.J. Jiménez. (2000) Chiral separation of four 1,3-dioxolane derivatives by supercritical fluid chromatography on an amylose-based column. Journal of Chromatography A 871:1-2, pages 127-137.
Crossref
Zdzis?aw Chilmonczyk, Hanna Ksyci?ska, M. Mazgajska & Hassan Y. Aboul-Enein. (1999) Enantioselective separation of 1,4-disubstituted piperazine derivatives on two cellulose Chiralcel OD and OJ and one amylose Chiralpak AD chiral selectors. Chirality 11:10, pages 790-794.
Crossref

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