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Pharmaceutical Development and Technology Volume 22, 2017 - Issue 4: Issue Theme: Topical and transdermal formulations and drug delivery systems
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Research Article

Monocyclic monoterpenes as penetration enhancers of ligustrazine hydrochloride for dermal delivery

Jiaoying WangState Key Laboratory of Natural Medicines, China Pharmaceutical University, Nanjing, PR China;
,
Cuilan DongThe People’s Hospital of Zhangqiu, Zhangqiu, PR China;
,
Zijing SongState Key Laboratory of Natural Medicines, China Pharmaceutical University, Nanjing, PR China;
,
Wenjun ZhangState Key Laboratory of Natural Medicines, China Pharmaceutical University, Nanjing, PR China;
,
Xin HeSchool of Pharmacy, Nanjing University of Chinese Medicine, Nanjing, PR China;
,
Runqi ZhangState Key Laboratory of Natural Medicines, China Pharmaceutical University, Nanjing, PR China;
,
Changrun GuoState Key Laboratory of Natural Medicines, China Pharmaceutical University, Nanjing, PR China;
,
Chunfeng ZhangState Key Laboratory of Natural Medicines, China Pharmaceutical University, Nanjing, PR China; ;Tang Center of Herbal Medicine Research and Department of Anesthesia & Critical Care, University of Chicago, Chicago, IL, USACorrespondence[email protected] [email protected]
,
Fei LiState Key Laboratory of Natural Medicines, China Pharmaceutical University, Nanjing, PR China; Correspondence[email protected] [email protected]
,
Chongzhi WangTang Center of Herbal Medicine Research and Department of Anesthesia & Critical Care, University of Chicago, Chicago, IL, USA
&
Chunsu YuanTang Center of Herbal Medicine Research and Department of Anesthesia & Critical Care, University of Chicago, Chicago, IL, USA
 show all
Pages 571-577 | Received 29 Jan 2016, Accepted 30 Mar 2016, Published online: 07 Jun 2016

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Mariia Nesterkina, Sergii Smola & Iryna Kravchenko. (2019) Effect of esters based on terpenoids and GABA on fluidity of phospholipid membranes. Journal of Liposome Research 29:3, pages 239-246.
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Xiao Zheng, Fei Wu, Xiao Lin, Lan Shen & Yi Feng. (2018) Developments in drug delivery of bioactive alkaloids derived from traditional Chinese medicine. Drug Delivery 25:1, pages 398-416.
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Min Ma, Hong-Jie Di, Hui Zhang, Jun-Hong Yao, Jie Dong, Guo-Jun Yan, Hong-Zhi Qiao & Jun Chen. (2017) Development of phospholipid vesicle-based permeation assay models capable of evaluating percutaneous penetration enhancing effect. Drug Development and Industrial Pharmacy 43:12, pages 2055-2063.
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Articles from other publishers (13)

Izi Vieira Nunes Cunha, Angela Machado Campos, Adriana Passarella Gerola & Thiago Caon. (2023) Effect of invasome composition on membrane fluidity, vesicle stability and skin interactions. International Journal of Pharmaceutics 646, pages 123472.
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Natalia Schafer, Radosław Balwierz, Paweł Biernat, Wioletta Ochędzan-Siodłak & Jacek Lipok. (2023) Natural Ingredients of Transdermal Drug Delivery Systems as Permeation Enhancers of Active Substances through the Stratum Corneum . Molecular Pharmaceutics 20:7, pages 3278-3297.
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Yafang Zhang, Linfeng He, Cheng Ma, Cheng Wang, Honglin Zhou, Chaocheng Guo, Lihong Gong, Yan Wan, Cheng Peng & Yunxia Li. (2022) Research progress on the pharmacy of tetramethylpyrazine and its pharmacological activity in cardiovascular and cerebrovascular diseases. Journal of Pharmacy and Pharmacology 74:6, pages 843-860.
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Ayu Masyita, Reka Mustika Sari, Ayun Dwi Astuti, Budiman Yasir, Nur Rahma Rumata, Talha Bin Emran, Firzan Nainu & Jesus Simal-Gandara. (2022) Terpenes and terpenoids as main bioactive compounds of essential oils, their roles in human health and potential application as natural food preservatives. Food Chemistry: X 13, pages 100217.
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Ding Zhang, Boqi Chen, Qingke Mu, Wei Wang, Kaili Liang, Liyan Wang & Qing Wang. (2021) Topical delivery of gambogic acid assisted by the combination of low-frequency ultrasound and chemical enhancers for chemotherapy of cutaneous melanoma. European Journal of Pharmaceutical Sciences 166, pages 105975.
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Wenqiang Yang, Xu Chen, Yanli Li, Shaofen Guo, Zhen Wang & Xiuling Yu. (2020) Advances in Pharmacological Activities of Terpenoids. Natural Product Communications 15:3, pages 1934578X2090355.
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Jianming Liang, Ying Zhu, Caifang Gao, Chengli Ling, Jing Qin, Qi Wang, Yongzhuo Huang, Weigen Lu & Jianxin Wang. (2019) Menthol-modified BSA nanoparticles for glioma targeting therapy using an energy restriction strategy. NPG Asia Materials 11:1.
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Xiao-Qian Niu, Dan-Ping Zhang, Qiong Bian, Xing-Fu Feng, Hao Li, Yue-Feng Rao, Yong-Mei Shen, Fu-Neng Geng, An-Ran Yuan, Xiao-Ying Ying & Jian-Qing Gao. (2019) Mechanism investigation of ethosomes transdermal permeation. International Journal of Pharmaceutics: X 1, pages 100027.
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Xue-min Zhu, Yu Li, Fei Xu, Wei Gu, Guo-jun Yan, Jie Dong & Jun Chen. (2019) Skin Electrical Resistance Measurement of Oxygen-Containing Terpenes as Penetration Enhancers: Role of Stratum Corneum Lipids. Molecules 24:3, pages 523.
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Xingxing Dai, Ran Wang, Zhimin Wu, Shujuan Guo, Chang Yang, Lina Ma, Liping Chen, Xinyuan Shi & Yanjiang Qiao. (2018) Permeation-enhancing effects and mechanisms of borneol and menthol on ligustrazine: A multiscale study using in vitro and coarse-grained molecular dynamics simulation methods. Chemical Biology & Drug Design 92:5, pages 1830-1837.
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Terrence E. O’Brien, Steven J. Bertolani, Yue Zhang, Justin B. Siegel & Dean J. Tantillo. (2018) Predicting Productive Binding Modes for Substrates and Carbocation Intermediates in Terpene Synthases—Bornyl Diphosphate Synthase As a Representative Case. ACS Catalysis 8:4, pages 3322-3330.
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Shuai Yan, Yinzi Yue, Lili Yang, Yaoyao Bian, Jin Yue & Li Zeng. (2017) Development of an Electrochemical Sensor for Determination of Ligustrazine Based on Nitrogen-Doped Multi-Walled Carbon Nanotube. International Journal of Electrochemical Science 12:9, pages 8495-8503.
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Jun Chen, Qiu-Dong Jiang, Ya-Ping Chai, Hui Zhang, Pei Peng & Xi-Xiong Yang. (2016) Natural Terpenes as Penetration Enhancers for Transdermal Drug Delivery. Molecules 21:12, pages 1709.
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