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Pharmaceutical Development and Technology Volume 23, 2018 - Issue 1: Issue Theme: Anticancer drug formulation and delivery: Tumor targeting and cytotoxicity
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Research Article

Gambogic acid-loaded PEG–PCL nanoparticles act as an effective antitumor agent against gastric cancer

Dinghu ZhangThe Comprehensive Cancer Centre of Drum Tower Hospital, Clinical College of Traditional Chinese and Western Medicine, Nanjing University of Chinese Medicine, Nanjing, China; View further author information
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Zhengyun ZouThe Comprehensive Cancer Centre of Drum Tower Hospital, Medical School of Nanjing University & Clinical Cancer Institute of Nanjing University, Nanjing, ChinaView further author information
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Wei RenThe Comprehensive Cancer Centre of Drum Tower Hospital, Medical School of Nanjing University & Clinical Cancer Institute of Nanjing University, Nanjing, ChinaView further author information
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Hanqing QianThe Comprehensive Cancer Centre of Drum Tower Hospital, Medical School of Nanjing University & Clinical Cancer Institute of Nanjing University, Nanjing, ChinaView further author information
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Qianfeng ChengThe Comprehensive Cancer Centre of Drum Tower Hospital, Medical School of Nanjing University & Clinical Cancer Institute of Nanjing University, Nanjing, ChinaView further author information
,
Liulian JiThe Comprehensive Cancer Centre of Drum Tower Hospital, Clinical College of Traditional Chinese and Western Medicine, Nanjing University of Chinese Medicine, Nanjing, China; View further author information
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Baorui LiuThe Comprehensive Cancer Centre of Drum Tower Hospital, Clinical College of Traditional Chinese and Western Medicine, Nanjing University of Chinese Medicine, Nanjing, China; ;The Comprehensive Cancer Centre of Drum Tower Hospital, Medical School of Nanjing University & Clinical Cancer Institute of Nanjing University, Nanjing, ChinaView further author information
&
Qin LiuThe Comprehensive Cancer Centre of Drum Tower Hospital, Medical School of Nanjing University & Clinical Cancer Institute of Nanjing University, Nanjing, ChinaCorrespondence[email protected] [email protected]
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Pages 33-40 | Received 10 Nov 2016, Accepted 08 Jan 2017, Published online: 03 Mar 2017

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Yuling Liu, Yingchong Chen, Longfei Lin & Hui Li. (2020) Gambogic Acid as a Candidate for Cancer Therapy: A Review. International Journal of Nanomedicine 15, pages 10385-10399.
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Dinghu Zhang, Yanhong Chu, Hanqing Qian, Lingyu Qian, Jie Shao, Qiuping Xu, Lixia Yu, Rutian Li, Quanan Zhang, Fenglei Wu, Baorui Liu & Qin Liu. (2020) Antitumor Activity of Thermosensitive Hydrogels Packaging Gambogic Acid Nanoparticles and Tumor-Penetrating Peptide iRGD Against Gastric Cancer. International Journal of Nanomedicine 15, pages 735-747.
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Dereje Kebebe, Yumei Wu, Bing Zhang, Jian Yang, Yuanyuan Liu, Xinyue Li, Zhe Ma, Peng Lu, Zhidong Liu & Jiawei Li. (2019) Dimeric c(RGD) peptide conjugated nanostructured lipid carriers for efficient delivery of Gambogic acid to breast cancer. International Journal of Nanomedicine 14, pages 6179-6195.
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Shijie Xu, Fangbo Cui, Dafu Huang, Dinghu Zhang, Anqing Zhu, Xia Sun, Yiming Cao, Sheng Ding, Yao Wang, Eryun Gao & Fenglin Zhang. (2019) PD-L1 monoclonal antibody-conjugated nanoparticles enhance drug delivery level and chemotherapy efficacy in gastric cancer cells. International Journal of Nanomedicine 14, pages 17-32.
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Ruixi He, Buyun Jia, Daiyin Peng & Weidong Chen. (2023) Caged Polyprenylated Xanthones in Garcinia hanburyi and the Biological Activities of Them. Drug Design, Development and Therapy Volume 17, pages 3625-3660.
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Ying Ji, Juan Li, Shilin Xiao, Hiu Yee Kwan, Zhaoxiang Bian & Chih-Chang Chu. (2023) Optimization of amino acid-based poly(ester urea urethane) nanoparticles for the systemic delivery of gambogic acid for treating triple negative breast cancer. Biomaterials Science 11:12, pages 4370-4384.
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Akanksha Behl, Virinder S. Parmar, Shashwat Malhotra & Anil K. Chhillar. (2020) Biodegradable diblock copolymeric PEG-PCL nanoparticles: Synthesis, characterization and applications as anticancer drug delivery agents. Polymer 207, pages 122901.
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Griffin Pauli, Wei-Lun Tang & Shyh-Dar Li. (2019) Development and Characterization of the Solvent-Assisted Active Loading Technology (SALT) for Liposomal Loading of Poorly Water-Soluble Compounds. Pharmaceutics 11:9, pages 465.
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Vahid Taghipour-Sabzevar, Tahere Sharifi & Mehrdad Moosazadeh Moghaddam. (2019) Polymeric nanoparticles as carrier for targeted and controlled delivery of anticancer agents. Therapeutic Delivery 10:8, pages 527-550.
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Ye Yang, Hanxu Cai, Xiuyan Yuan, Huihui Xu, Yingying Hu, Xue Rui, Jingjing Wu, Jing Chen, Jing Li, Xiangdong Gao & Dengke Yin. (2018) Efficient Targeting Drug Delivery System for Lewis Lung Carcinoma, Leading to Histomorphological Abnormalities Restoration, Physiological and Psychological Statuses Improvement, and Metastasis Inhibition. Molecular Pharmaceutics 15:5, pages 2007-2016.
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Tongtong Zhang, Yanming Chen, Yuanyuan Ge, Yuzhen Hu, Miao Li & Yiguang Jin. (2018) Inhalation treatment of primary lung cancer using liposomal curcumin dry powder inhalers. Acta Pharmaceutica Sinica B 8:3, pages 440-448.
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Kumar Ganesan & Baojun Xu. (2017) Telomerase Inhibitors from Natural Products and Their Anticancer Potential. International Journal of Molecular Sciences 19:1, pages 13.
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