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Pharmaceutical Development and Technology Volume 23, 2018 - Issue 7: Issue Theme: Solubility enhancement and solid-state characterisation
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Research Article

The use of albumin solid dispersion to enhance the solubility of unionizable drugs

Mouhamad KhoderDrug Discovery, Delivery and Patient Care (DDDPC) Theme, School of Life Sciences, Pharmacy and Chemistry, Kingston University London, Kingston Upon Thames, UK; Correspondence[email protected], [email protected]
,
Hamdy AbdelkaderDepartment of Pharmaceutics, Faculty of Pharmacy, Minia University, Minia, Egypt;
,
Amr ElShaerDrug Discovery, Delivery and Patient Care (DDDPC) Theme, School of Life Sciences, Pharmacy and Chemistry, Kingston University London, Kingston Upon Thames, UK;
,
Ayman KaramInstitute of Chemistry of Poitiers: Materials and Natural Resources, Catalysis and Unconventional Media’s Team University of Poitiers, France;
,
Mohammad NajlahFaculty of Medical Science, Anglia Ruskin University, Bishops Hall Lane, Chelmsford, UK;
&
Raid G. AlanyDrug Discovery, Delivery and Patient Care (DDDPC) Theme, School of Life Sciences, Pharmacy and Chemistry, Kingston University London, Kingston Upon Thames, UK; ;School of Pharmacy, The University of Auckland, Auckland, New Zealand
Pages 732-738 | Received 01 Feb 2017, Accepted 13 Jun 2017, Published online: 24 Aug 2017

Citations (7)

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Read on this site (2)

Barzan Osi, Mouhamad Khoder, Ali A. Al-Kinani & Raid G. Alany. (2022) Pharmaceutical, biomedical and ophthalmic applications of biodegradable polymers (BDPs): literature and patent review. Pharmaceutical Development and Technology 27:3, pages 341-356.
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Xiao Yue, Yingtong Cui, Ting Yuan, Zhengwei Huang, Ying Huang, Xuejuan Zhang, Chen Wang, Guanlin Wang, Ruifeng Liang, Chunxia Liu, Xin Pan & Chuanbin Wu. (2020) Calcitriol tablets with hybrid lipid-based solid dispersions with enhanced stability and content uniformity. Pharmaceutical Development and Technology 25:7, pages 899-907.
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Articles from other publishers (5)

Heba A. Abou-Taleb, Mai E. Shoman, Tarek Saad Makram, Jelan A. Abdel-Aleem & Hamdy Abdelkader. (2023) Exploration of the Safety and Solubilization, Dissolution, Analgesic Effects of Common Basic Excipients on the NSAID Drug Ketoprofen. Pharmaceutics 15:2, pages 713.
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Kıvılcım Öztürk, Fatma Betül Arslan, Süleyman Can Öztürk & Sema Çalış. (2022) Mixed micelles formulation for carvedilol delivery: In-vitro characterization and in-vivo evaluation. International Journal of Pharmaceutics 611, pages 121294.
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Heba A. Abou-Taleb, Zeinab Fathalla & Hamdy Abdelkader. (2020) Comparative studies of the effects of novel excipients amino acids with cyclodextrins on enhancement of dissolution and oral bioavailability of the non-ionizable drug carbamazepine. European Journal of Pharmaceutical Sciences 155, pages 105562.
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Yue Li, Ahmad M. N. AlhendiMei-Chun YehMina ElahyFernando S. SantiagoNandan P. Deshpande, Ben WuEnoch Chan, Shafqat InamLeonel Prado-LourencoJessica MarchandRohan D. Joyce, Lorna E. Wilkinson-WhiteMark J. Raftery, Meidong ZhuSamuel J. Adamson, François BarnatKaren Viaud-QuentricJim SocklerJoel P. Mackay, Andrew ChangPaul MitchellSebastian M. MarcuccioLevon M. Khachigian. (2020) Thermostable small-molecule inhibitor of angiogenesis and vascular permeability that suppresses a pERK-FosB/ΔFosB–VCAM-1 axis. Science Advances 6:31.
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Mouhamad Khoder, Henry GbormoiSr.Sr., Ali Ryan, Ayman Karam & Raid Alany. (2019) Potential Use of the Maillard Reaction for Pharmaceutical Applications: Gastric and Intestinal Controlled Release Alginate-Albumin Beads. Pharmaceutics 11:2, pages 83.
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