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Pharmaceutical Development and Technology Volume 24, 2019 - Issue 6
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Research Article

Revaprazan-loaded surface-modified solid dispersion: physicochemical characterization and in vivo evaluation

Jong Hyuck ParkCollege of Pharmacy & Institute of Pharmaceutical Science and Technology, Hanyang University, Ansan, South Korea; ORCID Iconhttp://orcid.org/0000-0003-4424-6507View further author information
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Jung Hyun ChoCollege of Pharmacy & Institute of Pharmaceutical Science and Technology, Hanyang University, Ansan, South Korea; ORCID Iconhttp://orcid.org/0000-0002-0489-2531View further author information
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Dong Shik KimCollege of Pharmacy & Institute of Pharmaceutical Science and Technology, Hanyang University, Ansan, South Korea; ORCID Iconhttp://orcid.org/0000-0001-7081-7161View further author information
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Jung Suk KimCollege of Pharmacy & Institute of Pharmaceutical Science and Technology, Hanyang University, Ansan, South Korea; ORCID Iconhttp://orcid.org/0000-0002-6235-3157View further author information
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Fakhar Ud DinDepartment of Pharmacy, Quaid-I-Azam University, Islamabad, Pakistan; ORCID Iconhttp://orcid.org/0000-0001-9537-4897View further author information
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Jong Oh KimCollege of Pharmacy, Yeungnam University, Gyongsan, South Korea; ORCID Iconhttp://orcid.org/0000-0002-4929-851XView further author information
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Chul Soon YongCollege of Pharmacy, Yeungnam University, Gyongsan, South Korea; ORCID Iconhttp://orcid.org/0000-0002-9242-2117View further author information
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Yu Seok YounSchool of Pharmacy, Sungkyunkwan University, Suwon, South Korea; ORCID Iconhttp://orcid.org/0000-0001-9099-9230View further author information
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Kyung Taek OhCollege of Pharmacy, Chung-Ang University, Seoul, South Korea; ORCID Iconhttp://orcid.org/0000-0002-4379-7238View further author information
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Dong Wuk KimCollege of Pharmacy & Institute of Pharmaceutical Science and Technology, Hanyang University, Ansan, South Korea; ;College of Pharmacy, Kyungpook National University, Daegu, South KoreaCorrespondence[email protected]
ORCID Iconhttp://orcid.org/0000-0001-8471-6759View further author information
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Han-Gon ChoiCollege of Pharmacy & Institute of Pharmaceutical Science and Technology, Hanyang University, Ansan, South Korea; Correspondence[email protected]
ORCID Iconhttp://orcid.org/0000-0002-2318-387XView further author information
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Pages 788-793 | Received 31 Jul 2018, Accepted 16 Mar 2019, Published online: 24 Apr 2019

Citations (19)

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Xuemei Luo, Aiman Saleem, Uswa Shafique, Sadia Sarwar, Kalim Ullah, Muhammad Imran, Alam Zeb & Fakhar ud Din. (2023) Rivaroxaban-loaded SLNs with treatment potential of deep vein thrombosis: in-vitro, in-vivo, and toxicity evaluation. Pharmaceutical Development and Technology 28:7, pages 625-637.
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Yoon Tae Goo, Min Song Kim, Ji Yeh Choi, Gi Hyeong Sin, Sun Ho Hong, Chang Hyun Kim & Young Wook Choi. (2023) A cochleate formulation optimized by D-optimal mixture design enhances oral bioavailability of Revaprazan. Journal of Liposome Research 0:0, pages 1-13.
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Raj J. Ahiwale, Bothiraja Chellampillai & Atmaram P. Pawar. (2022) Investigation of novel sorafenib tosylate loaded biomaterial based nano-cochleates dispersion system for treatment of hepatocellular carcinoma. Journal of Dispersion Science and Technology 43:10, pages 1568-1586.
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Yoon Tae Goo, Cheol-Ki Sa, Min Song Kim, Gi Hyeong Sin, Chang Hyun Kim, Hyeon Kyun Kim, Myung Joo Kang, Sangkil Lee & Young Wook Choi. (2022) Enhanced dissolution and bioavailability of revaprazan using self-nanoemulsifying drug delivery system. Pharmaceutical Development and Technology 27:4, pages 414-424.
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Hyuk Jun Cho, Mi Ran Woo, Jung Hyun Cho, Yong Kim$suffix/text()$suffix/text() & Han-Gon Choi. (2022) Novel dapagliflozin di-L-proline cocrystal-loaded tablet: preparation, physicochemical characterization, and pharmacokinetics in beagle dogs and mini-pigs. Pharmaceutical Development and Technology 27:3, pages 331-340.
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Jung Suk Kim, Fakhar ud Din, Sang Min Lee, Dong Shik Kim, Mi Ran Woo, Seunghyun Cheon, Sang Hun Ji, Jong Oh Kim, Yu Seok Youn, Kyung Taek Oh, Soo-Jeong Lim, Sung Giu Jin & Han-Gon Choi. (2021) Comparison of Three Different Aqueous Microenvironments for Enhancing Oral Bioavailability of Sildenafil: Solid Self-Nanoemulsifying Drug Delivery System, Amorphous Microspheres and Crystalline Microspheres. International Journal of Nanomedicine 16, pages 5797-5810.
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Yoon Tae Goo, Cheol-Ki Sa, Ji Yeh Choi, Min Song Kim, Chang Hyun Kim, Hyeon Kyun Kim & Young Wook Choi. (2021) Development of a Solid Supersaturable Micelle of Revaprazan for Improved Dissolution and Oral Bioavailability Using Box-Behnken Design. International Journal of Nanomedicine 16, pages 1245-1259.
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Dae Woong Ko, Jung Hyun Cho & Han-Gon Choi. (2021) Development of rebamipide-loaded spray-dried microsphere using distilled water and meglumine: physicochemical characterization and pharmacokinetics in rats. Pharmaceutical Development and Technology 26:6, pages 701-708.
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Articles from other publishers (11)

Maimoona Malik, Zakir Ali, Salman Khan, Alam Zeb, Fakhar ud Din, Ali H. Alamri & Ahmed A. Lahiq. (2024) TPGS-PLA nanomicelles for targeting lung cancer; synthesis, characterization, and in vitro antitumor efficacy. Journal of Drug Delivery Science and Technology 91, pages 105238.
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Hadiqa Nazish Raja, Fakhar ud Din, Kanwal Shabbir, Salman Khan, Ali H. Alamri, Ahmed Abdullah Al Awadh, Ahmed A. Lahiq & Ali Alasiri. (2023) Sodium alginate-based smart gastro-retentive drug delivery system of revaprazan loaded SLNs; Formulation and characterization. International Journal of Biological Macromolecules 253, pages 127402.
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Zhonghua Guo, Rabia Afza, Muhammad Moneeb Khan, Saif Ullah Khan, Muhammad Waseem Khan, Zakir Ali, Sibgha Batool & Fakhar ud Din. (2023) Investigation of the treatment potential of Raloxifene-loaded polymeric nanoparticles in osteoporosis: In-vitro and in-vivo analyses. Heliyon 9:9, pages e20107.
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SUMIT KUMAR SAHA, AMITA JOSHI, ROMI SINGH & KIRAN DUBEY. (2023) ENHANCED SOLUBILITY AND DISSOLUTION BY SURFACE-MODIFIED SOLID DISPERSION OF ALECTINIB HYDROCHLORIDE. International Journal of Applied Pharmaceutics, pages 257-265.
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Zhonghua Guo, Ping Qi, Donghong Pei & Xiuju Zhang. (2022) Raloxifene-loaded solid lipid nanoparticles decorated gel with enhanced treatment potential of osteoporosis. Journal of Drug Delivery Science and Technology 75, pages 103733.
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Jung Suk Kim, Yoo Jin Choi, Mi Ran Woo, Seunghyun Cheon, Sang Hun Ji, Daseul Im, Fakhar ud Din, Jong Oh. Kim, Yu Seok Youn, Kyung Taek Oh, Soo-Jeong Lim, Sung Giu Jin & Han-Gon Choi. (2021) New potential application of hydroxypropyl-β-cyclodextrin in solid self-nanoemulsifying drug delivery system and solid dispersion. Carbohydrate Polymers 271, pages 118433.
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Surendra Poudel & Dong Wuk Kim. (2021) Developing pH-Modulated Spray Dried Amorphous Solid Dispersion of Candesartan Cilexetil with Enhanced In Vitro and In Vivo Performance. Pharmaceutics 13:4, pages 497.
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Ji Eun Choi, Jung Suk Kim, Min-Jong Choi, Kyungho Baek, Mi Ran Woo, Jong Oh Kim, Han-Gon Choi & Sung Giu Jin. (2021) Effects of different physicochemical characteristics and supersaturation principle of solidified SNEDDS and surface-modified microspheres on the bioavailability of carvedilol. International Journal of Pharmaceutics 597, pages 120377.
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Jung Suk Kim, Fakhar ud Din, Sang Min Lee, Dong Shik Kim, Yoo Jin Choi, Mi Ran Woo, Jong Oh Kim, Yu Seok Youn, Sung Giu Jin & Han-Gon Choi. (2021) Comparative study between high-pressure homogenisation and Shirasu porous glass membrane technique in sildenafil base-loaded solid SNEDDS: Effects on physicochemical properties and in vivo characteristics. International Journal of Pharmaceutics 592, pages 120039.
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Jung Hyun Cho & Han-Gon Choi. (2020) Development of novel tenofovir disoproxil phosphate salt with stability enhancement and bioequivalence to the commercial tenofovir disoproxil fumarate salt in rats and beagle dogs. International Journal of Pharmaceutics 576, pages 118957.
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Kwon, Giri, Song, Bae, Lee & Kim. (2019) Spray-Dried Amorphous Solid Dispersions of Atorvastatin Calcium for Improved Supersaturation and Oral Bioavailability. Pharmaceutics 11:9, pages 461.
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