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Review Articles

Mucoadhesive formulations: innovations, merits, drawbacks, and future outlook

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Pages 797-814 | Received 14 Aug 2019, Accepted 06 Apr 2020, Published online: 25 Apr 2020

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Radha Kulkarni, Suraj Fanse & Diane J. Burgess. (2023) Mucoadhesive drug delivery systems: a promising non-invasive approach to bioavailability enhancement. Part I: biophysical considerations. Expert Opinion on Drug Delivery 20:3, pages 395-412.
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Varsha V. Nair, Pablo Cabrera, Constanza Ramírez-Lecaros, Miguel O. Jara, David J. Brayden & Javier O. Morales. (2023) Buccal delivery of small molecules and biologics: Of mucoadhesive polymers, films, and nanoparticles – An update. International Journal of Pharmaceutics 636, pages 122789.
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Sara Salatin, Mina Tarzamani, Afsaneh Farjami & Mitra Jelvehgari. (2022) Development and characterization of a novel mucoadhesive sol-gel suppository of sumatriptan: design, optimization, in vitro  and ex vivo evaluation for rectal drug delivery . Therapeutic Delivery 13:2, pages 95-108.
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Wesam W. Mustafa, John Fletcher, Mouhamad Khoder & Raid G. Alany. (2022) Solid Dispersions of Gefitinib Prepared by Spray Drying with Improved Mucoadhesive and Drug Dissolution Properties. AAPS PharmSciTech 23:1.
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Daniela A. Rodrigues, Sónia P. Miguel, Jorge Loureiro, Maximiano Ribeiro, Fátima Roque & Paula Coutinho. (2021) Oromucosal Alginate Films with Zein Nanoparticles as a Novel Delivery System for Digoxin. Pharmaceutics 13:12, pages 2030.
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Sushila Bhattarai, Dhayaneethie Perumal, Michael J. Rathbone, Craig R. Bunt & Raid G. Alany. (2021) On the Biocompatibility and Teat Retention of In Situ Gelling Intramammary Formulations: Cattle Mastitis Prevention and Treatment. Pharmaceutics 13:10, pages 1732.
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Ayah Mohammad Burhan, Butsabarat Klahan, Wayne Cummins, Vanessa Andrés-Guerrero, Mark E. Byrne, Niall J. O’Reilly, Anuj Chauhan, Laurence Fitzhenry & Helen Hughes. (2021) Posterior Segment Ophthalmic Drug Delivery: Role of Muco-Adhesion with a Special Focus on Chitosan. Pharmaceutics 13:10, pages 1685.
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Thomas E. Robinson, Richard J. A. Moakes & Liam M. Grover. (2021) Low Acyl Gellan as an Excipient to Improve the Sprayability and Mucoadhesion of Iota Carrageenan in a Nasal Spray to Prevent Infection With SARS-CoV-2. Frontiers in Medical Technology 3.
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