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Original Articles

Cigarette Smoke, Inflammation, and Lung Injury: A Mechanistic Perspective

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Pages 45-64 | Published online: 31 Dec 2008

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (22)

Priya Upadhyay, Ching-Wen Wu, Alexa Pham, Amir A. Zeki, Christopher M. Royer, Urmila P. Kodavanti, Minoru Takeuchi, Hasan Bayram & Kent E. Pinkerton. (2023) Animal models and mechanisms of tobacco smoke-induced chronic obstructive pulmonary disease (COPD). Journal of Toxicology and Environmental Health, Part B 26:5, pages 275-305.
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Seon-Bong Lee, Ju-Hyeong Kim, Myung-Haing Cho, Eun-Sang Choe, Kwang-Sik Kim & Soon-Mi Shim. (2017) Impact of commercial cigarette smoke condensate on brain tissue co-cultured with astrocytes and blood–brain barrier endothelial cells. Journal of Toxicology and Environmental Health, Part A 80:10-12, pages 533-541.
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Martina Piasek, Jasna Jurasović, Ankica Sekovanić, Nataša Brajenović, Irena Brčić Karačonji, Anja Mikolić, Antonija Sulimanec Grgec & Sandra Stasenko. (2016) Placental cadmium as an additional noninvasive bioindicator of active maternal tobacco smoking. Journal of Toxicology and Environmental Health, Part A 79:11, pages 443-446.
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Nataša Brajenović, Irena Brčić Karačonji & Aleksandar Bulog. (2015) Evaluation of Urinary Btex, Nicotine, and Cotinine as Biomarkers of Airborne Pollutants in Nonsmokers and Smokers. Journal of Toxicology and Environmental Health, Part A 78:17, pages 1133-1136.
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Ju-Hyeong Kim, Myung-Haing Cho, Kyung-Chul Choi, Kyuhong Lee, Kwang-Sik Kim & Soon-Mi Shim. (2015) Oxidative Stress Induced by Cigarette Smoke Extracts in Human Brain Cells (T98G) and Human Brain Microvascular Endothelial Cells (HBMEC) in Mono- and Co-Culture. Journal of Toxicology and Environmental Health, Part A 78:15, pages 1019-1027.
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Ijaz Malook, Amir Atlas, Shafiq ur Rehman, Wenyi Wang & Muhammad Jamil. (2014) Smoke alleviates adverse effects induced by stress on rice. Toxicological & Environmental Chemistry 96:5, pages 755-767.
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Sheung P. Ng, Allen E. Silverstone, Zhi-Wei Lai & Judith T. Zelikoff. (2013) Prenatal Exposure to Cigarette Smoke Alters Later-Life Antitumor Cytotoxic T-Lymphocyte (CTL) Activity Via Possible Changes in T-Regulatory Cells. Journal of Toxicology and Environmental Health, Part A 76:19, pages 1096-1110.
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Mir-Jamal Hosseini, Parvaneh Naserzadeh, Ahmad Salimi & Jalal Pourahmad. (2013) Toxicity of cigarette smoke on isolated lung, heart, and brain mitochondria: induction of oxidative stress and cytochrome c release. Toxicological & Environmental Chemistry 95:9, pages 1624-1637.
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Solange A. Pacheco, Vukosava M. Torres, Henriqueta Louro, Filomena Gomes, Carlos Lopes, Nelson Marçal, Elsa Fragoso, Carla Martins, Cátia L. Oliveira, Manuela Hagenfeldt, António Bugalho-Almeida, Deborah Penque & Tânia Simões. (2013) Effects of Occupational Exposure to Tobacco Smoke: Is There a Link Between Environmental Exposure and Disease?. Journal of Toxicology and Environmental Health, Part A 76:4-5, pages 311-327.
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Vanitha Bhoopalan, Sung Gu Han, Mrudang M. Shah, David M. Thomas & Deepak K. Bhalla. (2013) Tobacco smoke modulates ozone-induced toxicity in rat lungs and central nervous system. Inhalation Toxicology 25:1, pages 21-28.
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Janel R. Harting, Angela Gleason, Debra J. Romberger, Susanna G. Von Essen, Fang Qiu, Neil Alexis & Jill A. Poole. (2012) Chronic Obstructive Pulmonary Disease Patients Have Greater Systemic Responsiveness to Ex Vivo Stimulation with Swine Dust Extract and its Components Versus Healthy Volunteers. Journal of Toxicology and Environmental Health, Part A 75:24, pages 1456-1470.
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Larissa Helena Lobo Torres, Wallace Luiz Moreira, Raphael Caio Tamborelli Garcia, Raquel Annoni, Ana Laura Nicoletti Carvalho, Simone Aparecida Teixeira, Maurílio Pacheco-Neto, Marcelo Nicolas Muscará, Rosana Camarini, Ana Paula de Melo Loureiro, Mauricio Yonamine, Thais Mauad & Tania Marcourakis. (2012) Environmental Tobacco Smoke Induces Oxidative Stress in Distinct Brain Regions of Infant Mice. Journal of Toxicology and Environmental Health, Part A 75:16-17, pages 971-980.
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Solange A. Pacheco, Fátima Aguiar, Patrícia Ruivo, Maria Carmo Proença, Michael Sekera, Deborah Penque & Tânia Simões. (2012) Occupational Exposure to Environmental Tobacco Smoke: A Study in Lisbon Restaurants. Journal of Toxicology and Environmental Health, Part A 75:13-15, pages 857-866.
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Joana Madureira, Ana Mendes, Sofia Almeida & João Paulo Teixeira. (2012) Positive Impact of the Portuguese Smoking Law on Respiratory Health of Restaurant Workers. Journal of Toxicology and Environmental Health, Part A 75:13-15, pages 776-787.
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Frank Hoffmeyer, Monika Raulf-Heimsoth, Martin Lehnert, Benjamin Kendzia, Sabine Bernard, Hans Berresheim, Maria Düser, Jana Henry, Tobias Weiss, Holger M. Koch, Beate Pesch, Thomas Brüning & The WELDOX Group. (2012) Impact of Different Welding Techniques on Biological Effect Markers in Exhaled Breath Condensate of 58 Mild Steel Welders. Journal of Toxicology and Environmental Health, Part A 75:8-10, pages 525-532.
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Cynthia A. Leifer & Rodney R. Dietert. (2011) Early life environment and developmental immunotoxicity in inflammatory dysfunction and disease. Toxicological & Environmental Chemistry 93:7, pages 1463-1485.
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Sung Gu Han, Vanitha Bhoopalan, Tolulola Akinbiyi, C. Gary Gairola & Deepak K. Bhalla. (2011) In Utero Tobacco Smoke Exposure Alters Pulmonary Responses of Newborn Rats to Ozone. Journal of Toxicology and Environmental Health, Part A 74:10, pages 668-677.
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Jenny S. Fusby, Michele D. Kassmeier, Victoria L. Palmer, Greg A. Perry, Dirk K. Anderson, Bryan T. Hackfort, Gwen K. Alvarez, Diane M. Cullen, Mohammed P. Akhter & Patrick C. Swanson. (2010) Cigarette smoke-induced effects on bone marrow B-cell subsets and CD4+:CD8+ T-cell ratios are reversed by smoking cessation: Influence of bone mass on immune cell response to and recovery from smoke exposure. Inhalation Toxicology 22:9, pages 785-796.
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