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Original Articles

Potential Effects of Chlorpyrifos on Fetal Growth Outcomes: Implications for Risk Assessment

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Pages 281-316 | Published online: 09 May 2012

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (3)

Kristin Shrader-Frechette & Christopher ChoGlueck. (2017) Pesticides, Neurodevelopmental Disagreement, and Bradford Hill’s Guidelines. Accountability in Research 24:1, pages 30-42.
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Richard Reiss, Ellen T. Chang, Rudy J. Richardson & Michael Goodman. (2015) A review of epidemiologic studies of low-level exposures to organophosphorus insecticides in non-occupational populations. Critical Reviews in Toxicology 45:7, pages 531-641.
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Carol J. Burns, Laura J. McIntosh, Pamela J. Mink, Anne M. Jurek & Abby A. Li. (2013) Pesticide Exposure and Neurodevelopmental Outcomes: Review of the Epidemiologic and Animal Studies. Journal of Toxicology and Environmental Health, Part B 16:3-4, pages 127-283.
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Articles from other publishers (28)

Muftau Shittu, Suleiman Folorunsho Ambali, Joseph Olusegun Ayo, Mohammed Umaru Kawu, Motunrayo Ganiyat Akande & Zainab Abdulmalik. (2023) Developmental deficits in male rat pups caused by maternal and dietary administration of chlorpyriphos and cypermethrin: Melatonin’s mitigating effect. Toxicology and Industrial Health 39:7, pages 398-405.
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Donghai Liang, Jonathan Batross, Nancy Fiedler, Tippawan Prapamontol, Panrapee Suttiwan, Parinya Panuwet, Warangkana Naksen, Brittney O. Baumert, Volha Yakimavets, Youran Tan, Priya D'Souza, Ampica Mangklabruks, Supattra Sittiwang, Kristsanachai Kaewthit, Kanyapak Kohsuwan, Nattawadee Promkam, Sureewan Pingwong, P. Barry Ryan, Dana Boyd Barr, Dana Boyd Barr, Nancy Fiedler, Tippawan Prapamontol, Panrapee Suttiwan, Warangkana Naksen, Parinya Panuwet, P. Barry Ryan, Kyle Steenland, Melissa M. Smarr, Brittney O. Baumert, Priya D'Souza, Grace Lee, Olya Yakimavets, Tamaria Hawkins, Margaret Sullivan, Pamela Ohman-Strickland, Mark Robson, Sompoch Iamsupasit, Wattasit Siriwong, Kathryn J. Barr, Rachel Greenwald, Carol Cheatham, Ampica Mangklapuark, Tanyaporn Kerdnoi, Namtip Srirak, Surat Hongsibsong, Supattra Sittiwang, Chayada Dokjunyam, Pimjuta Nimmapirat, Wathoosiri Promduang, Natabhol Jayakittivaraloes, Nattawadee Promkam, Sureewan Pingwong, Kewalin Kunsupa, Anchana Kantasri, Kritsanachai Kaewthit, Anchalee Wongkampaun, Nathaporn Thongjan, Kanyapak Kohsuwan, Ranuka Dawandee, Maytinee Chaimidchid, Sasiwimon Soonsawat, Kingpaka Sritongkom, Sakawrat Namakunna & Soythong Pinasu. (2022) Metabolome-wide association study of the relationship between chlorpyrifos exposure and first trimester serum metabolite levels in pregnant Thai farmworkers. Environmental Research 215, pages 114319.
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Frank Glover, Michael L. Eisenberg, Federico Belladelli, Francesco Del Giudice, Tony Chen, Evan Mulloy & W. Michael Caudle. (2022) The association between organophosphate insecticides and blood pressure dysregulation: NHANES 2013–2014. Environmental Health 21:1.
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Ensiyeh Taheri, Mohammad Mehdi Amin, Seyede Shahrbanoo Daniali, Ibrahim Abdollahpour, Ali Fatehizadeh & Roya Kelishadi. (2022) Health risk assessment of exposure to chlorpyrifos in pregnant women using deterministic and probabilistic approaches. PLOS ONE 17:1, pages e0262127.
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Arin A. Balalian, Xinhua Liu, Julie B. Herbstman, Sharon Daniel, Robin Whyatt, Virginia Rauh, Antonia M. Calafat, Ronald Wapner & Pam Factor-Litvak. (2021) Prenatal exposure to organophosphate and pyrethroid insecticides and the herbicide 2,4-dichlorophenoxyacetic acid and size at birth in urban pregnant women. Environmental Research 201, pages 111539.
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V. O. Yerkudov, D. V. Zaslavsky, A. P. Pugovkin, A. T. Matchanov, K. U. Rozumbetov, R. K. Dauletov, S. P. Esemuratova, I. I. Nazhimov & V. G. Puzyrev. (2020) ANTHROPOMETRIC CHARACTERISTICS OF YOUNG ADULTS IN AREAS WITH DIFFERENT ECOLOGICAL RISKS IN THE ARAL SEA REGION, UZBEKISTAN. Ekologiya cheloveka (Human Ecology) 27:10, pages 45-54.
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Kübra Eronat & Dilek Sağır. (2020) Protective effects of curcumin and Ganoderma lucidum on hippocampal damage caused by the organophosphate insecticide chlorpyrifos in the developing rat brain: Stereological, histopathological and immunohistochemical study. Acta Histochemica 122:7, pages 151621.
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Linlin Sai, Qiang Jia, Yecui Zhang, Ru Han, Xiao Geng, Gongchang Yu, Shumin Li, Hua Shao, Yuxin Zheng & Cheng Peng. (2020) Genome-wide analysis of DNA methylation in testis of male rat exposed to chlorpyrifos. Toxicology Research 9:4, pages 509-518.
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Allan S. Felsot. 2020. Information Resources in Toxicology. Information Resources in Toxicology 203 220 .
Anat Lan, Daniel Stein, Miguel Portillo, Debra Toiber & Ora Kofman. (2019) Impaired innate and conditioned social behavior in adult C57Bl6/J mice prenatally exposed to chlorpyrifos. Behavioral and Brain Functions 15:1.
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Jianqiu Guo, Jiming Zhang, Chunhua Wu, Shenliang Lv, Dasheng Lu, Xiaojuan Qi, Shuai Jiang, Chao Feng, Haixing Yu, Weijiu Liang, Xiuli Chang, Yubin Zhang, Hao Xu, Yang Cao, Guoquan Wang & Zhijun Zhou. (2019) Associations of prenatal and childhood chlorpyrifos exposure with Neurodevelopment of 3-year-old children. Environmental Pollution 251, pages 538-546.
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Kristin Shrader-Frechette. (2018) Normative Philosophy of Science: Responding to Special-Interest Science. Axiomathes 28:6, pages 679-693.
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Isaac A. Adedara, Olatunde Owoeye, Babajide O. Ajayi, Ifeoluwa O. Awogbindin, Joao B.T. Rocha & Ebenezer O. Farombi. (2018) Diphenyl diselenide abrogates chlorpyrifos-induced hypothalamic-pituitary-testicular axis impairment in rats. Biochemical and Biophysical Research Communications 503:1, pages 171-176.
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Russell L. Carr, Navatha Alugubelly & Afzaal N. Mohammed. 2018. Linking Environmental Exposure to Neurodevelopmental Disorders. Linking Environmental Exposure to Neurodevelopmental Disorders 145 188 .
David A. Jett, Michelle Guignet, Suangsuda Supasai & Pamela J. Lein. 2018. Handbook of Developmental Neurotoxicology. Handbook of Developmental Neurotoxicology 183 198 .
Miguel A. Sogorb, Encarnación Fuster, Eva del Río, Jorge Estévez & Eugenio Vilanova. (2016) Effects of mipafox, paraoxon, chlorpyrifos and its metabolite chlorpyrifos-oxon on the expression of biomarker genes of differentiation in D3 mouse embryonic stem cells. Chemico-Biological Interactions 259, pages 368-373.
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Oksana Lockridge, Robert B. NorgrenJr.Jr., Rudolph C. Johnson & Thomas A. Blake. (2016) Naturally Occurring Genetic Variants of Human Acetylcholinesterase and Butyrylcholinesterase and Their Potential Impact on the Risk of Toxicity from Cholinesterase Inhibitors. Chemical Research in Toxicology 29:9, pages 1381-1392.
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Anne Debost-Legrand, Charline Warembourg, Catherine Massart, Cécile Chevrier, Nathalie Bonvallot, Christine Monfort, Florence Rouget, Fabrice Bonnet & Sylvaine Cordier. (2016) Prenatal exposure to persistent organic pollutants and organophosphate pesticides, and markers of glucose metabolism at birth. Environmental Research 146, pages 207-217.
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Chengquan Lu, Xiaohui Liu, Chang Liu, Jian Wang, Chunna Li, Qi Liu, Yachen Li, Shuangyue Li, Shu Sun, Jinsong Yan & Jing Shao. (2015) Chlorpyrifos Induces MLL Translocations Through Caspase 3-Dependent Genomic Instability and Topoisomerase II Inhibition in Human Fetal Liver Hematopoietic Stem Cells . Toxicological Sciences 147:2, pages 588-606.
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Wenli Guo, Jie Zhang, Wenjun Li, Ming Xu & Sijin Liu. (2015) Disruption of iron homeostasis and resultant health effects upon exposure to various environmental pollutants: A critical review. Journal of Environmental Sciences 34, pages 155-164.
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Claire Joly Condette, Véronique Bach, Camille Mayeur, Jérôme Gay-Quéheillard & Hafida Khorsi-Cauet. (2015) Chlorpyrifos Exposure During Perinatal Period Affects Intestinal Microbiota Associated With Delay of Maturation of Digestive Tract in Rats. Journal of Pediatric Gastroenterology & Nutrition 61:1, pages 30-40.
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Susan M. Barlow, Frank M. Sullivan & Richard K. Miller. 2015. Drugs During Pregnancy and Lactation. Drugs During Pregnancy and Lactation 599 638 .
LI SUN, SHUPING ZHANG, WENLI GUO, WEI HE, YI QIAN, GUANGBO QU, HONG JI, HAIQIN RONG & SIJIN LIU. (2014) Sublethal exposure of organophosphate pesticide chlorpyrifos alters cellular iron metabolism in hepatocytes and macrophages. International Journal of Molecular Medicine 34:5, pages 1395-1400.
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Carmen Estevan, Encarnación Fuster, Eva del Río, David Pamies, Eugenio Vilanova & Miguel A. Sogorb. (2014) Organophosphorus Pesticide Chlorpyrifos and Its Metabolites Alter the Expression of Biomarker Genes of Differentiation in D3 Mouse Embryonic Stem Cells in a Comparable Way to Other Model Neurodevelopmental Toxicants. Chemical Research in Toxicology 27:9, pages 1487-1495.
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D. Koutroulakis, S. Sifakis, M.N. Tzatzarakis, A.K. Alegakis, E. Theodoropoulou, M.P. Kavvalakis, D. Kappou & A.M. Tsatsakis. (2014) Dialkyl phosphates in amniotic fluid as a biomarker of fetal exposure to organophosphates in Crete, Greece; association with fetal growth. Reproductive Toxicology 46, pages 98-105.
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Graciela Chiapella, Susana Genti-Raimondi & Gladis Magnarelli. (2014) Placental oxidative status in rural residents environmentally exposed to organophosphates. Environmental Toxicology and Pharmacology 38:1, pages 220-229.
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Susan R. Reutman & Juliana W. Meadows. 2013. Effects of Persistent and Bioactive Organic Pollutants on Human Health. Effects of Persistent and Bioactive Organic Pollutants on Human Health 237 314 .
Carmen Estevan, Eugenio Vilanova & Miguel A. Sogorb. (2013) Chlorpyrifos and its metabolites alter gene expression at non-cytotoxic concentrations in D3 mouse embryonic stem cells under in vitro differentiation: Considerations for embryotoxic risk assessment. Toxicology Letters 217:1, pages 14-22.
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