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Journal of Toxicology and Environmental Health, Part B
Critical Reviews
Volume 21, 2018 - Issue 4
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Articles

Polybrominated diphenyl ether (PBDE) neurotoxicity: a systematic review and meta-analysis of animal evidence

David C. DormanDepartment of Molecular and Biomedical Sciences, College of Veterinary Medicine, North Carolina State University, Raleigh, NC, USACorrespondence[email protected]
,
Weihsueh ChiuDepartment of Veterinary Integrative Biosciences, College of Veterinary Medicine, Texas A&M University, College Station, TX, USA
,
Barbara F. HalesDepartment of Pharmacology and Therapeutics, McGill University, Montreal, Quebec, Canada
,
Russ HauserDepartment of Environmental Health and Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, MA, USA
,
Kamin J. JohnsonPredictive Safety Center, Corteva Agriscience™, Agriculture Division of DowDuPont™, Indianapolis, IN, USA
,
Ellen MantusBoard on Environmental Studies and Toxicology at the National Academies of Sciences, Engineering, and Medicine, Washington DC, USA
,
Susan MartelBoard on Environmental Studies and Toxicology at the National Academies of Sciences, Engineering, and Medicine, Washington DC, USA
,
Karen A. RobinsonDepartment of Medicine, Johns Hopkins University, Baltimore, MD, USA
,
Andrew A. RooneyOffice of Health Assessment and Translation, Division of the National Toxicology Program, National Institute of Environmental Health Sciences, National Institutes of Health, Department of Health and Human Services, Research Triangle Park, NC, USA
,
Ruthann RudelSilent Spring Institute, Newton, MA, USA
,
Sheela SathyanarayanaDepartment of Pediatrics, University of Washington, Seattle Children’s Research Institute, SeattleWA, USA
,
Susan L. SchantzDepartment of Comparative Biosciences, College of Veterinary Medicine and Beckman Institute for Advanced Science and Technology, University of Illinois at Urbana-Champaign, Urbana, IL, USA
&
Katrina M. WatersBiological Sciences Division, Pacific Northwest National Laboratory, Richland, WA, USA
 show all
Pages 269-289 | Published online: 23 Oct 2018

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Gwyndolin M. Vail, Sabrina N. Walley, Ali Yasrebi, Angela Maeng, Kristie M. Conde & Troy A. Roepke. (2020) The interactions of diet-induced obesity and organophosphate flame retardant exposure on energy homeostasis in adult male and female mice. Journal of Toxicology and Environmental Health, Part A 83:11-12, pages 438-455.
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João Guilherme Costa, Bojana Vidovic, Nuno Saraiva, Maria do Céu Costa, Giorgia Del Favero, Doris Marko, Nuno G. Oliveira & Ana Sofia Fernandes. (2019) Contaminants: a dark side of food supplements?. Free Radical Research 53:sup1, pages 1113-1135.
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Veronica van der Schyff, Jiří Kalina, Annalisa Abballe, Anna Laura Iamiceli, Eva Govarts & Lisa Melymuk. (2023) Has Regulatory Action Reduced Human Exposure to Flame Retardants?. Environmental Science & Technology 57:48, pages 19106-19124.
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Alexandra E. Butler, Edwina Brennan, Daniel S. Drage, Thozhukat Sathyapalan & Stephen L. Atkin. (2023) Association of flame retardants, polybrominated diethyl ethers (PBDEs), with vitamin D in female subjects. Chemosphere 338, pages 139488.
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Ashley Y. Song, Elizabeth M. Kauffman, Ghassan B. Hamra, Aisha S. Dickerson, Lisa A. Croen, Irva Hertz-Picciotto, Rebecca J. Schmidt, Craig J. Newschaffer, M Daniele Fallin, Kristen Lyall & Heather E. Volk. (2023) Associations of prenatal exposure to a mixture of persistent organic pollutants with social traits and cognitive and adaptive function in early childhood: Findings from the EARLI study. Environmental Research 229, pages 115978.
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Sijie Xu, Junxia Wang, Dengxian Deng, Yueying Sun, Xuedong Wang & Zhanen Zhang. (2023) A pretreatment method combined matrix solid-phase dispersion with dispersive liquid–liquid micro-extraction for polybrominated diphenyl ethers in vegetables through quantitation of gas chromatography-tandem mass spectrometry (GC-MS). RSC Advances 13:23, pages 15772-15782.
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Zhiyuan Tian, Jing Li, Li Song, Li Xie, Dongjie Li, Tao Xia & Aiguo Wang. (2023) PBDE-47 induces impairment of mitochondrial biogenesis and subsequent neurotoxicity through miR-128-3p/PGC-1α axis. Toxicological Sciences 191:1, pages 123-134.
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Dave Arthur R. Robledo, Maricar S. Prudente, Socorro E. Aguja & Hisato Iwata. (2023) A meta-analysis of randomized controlled studies on the hepatoxicity induced by polybrominated diphenyl ethers (PBDEs) in rats and mice. Current Research in Toxicology 5, pages 100131.
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Bin Li, Jianghong Shi, Jiawei Zhang, Huanyu Tao, Hui Ge, Mengtao Zhang, Zonglin Xu & Ruijie Xiao. (2023) Occurrence and ecological risk assessment of 2,2′,4,4′-tetrabromodiphenyl ether and decabromodiphenyl ether in surface waters across China. Chemosphere 312, pages 137215.
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Hao Wang, Julia Y. Cui & Lucio G. Costa. 2023.
Yibo Yang, Lei Wang, Yuhao Zhao, Fuhao Ma, Ziyi Lin, Yingyu Liu, Zimei Dong, Guangwen Chen & Dezeng Liu. (2022) PBDEs disrupt homeostasis maintenance and regeneration of planarians due to DNA damage, proliferation and apoptosis anomaly. Ecotoxicology and Environmental Safety 248, pages 114287.
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Montse Marquès, Martí Nadal & José L. Domingo. (2022) Human exposure to polybrominated diphenyl ethers (PBDEs) through the diet: An update of the scientific literature. Food and Chemical Toxicology 167, pages 113322.
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Louise Ramhøj, Terje Svingen, Karen Mandrup, Ulla Hass, Søren Peter Lund, Anne Marie Vinggaard, Karin Sørig Hougaard & Marta Axelstad. (2022) Developmental exposure to the brominated flame retardant DE-71 reduces serum thyroid hormones in rats without hypothalamic-pituitary-thyroid axis activation or neurobehavioral changes in offspring. PLOS ONE 17:7, pages e0271614.
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Jianwei Zhao, Chengzhi Qin, Meiping Sui, Siyi Luo, Huanyun Zhang & Jiangwei Zhu. (2022) Understanding the mechanism of polybrominated diphenyl ethers reducing the anaerobic co-digestion efficiency of excess sludge and kitchen waste. Environmental Science and Pollution Research 29:27, pages 41357-41367.
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Samantha Schildroth, Kathryn M. Rodgers, Mark Strynar, James McCord, Giulia Poma, Adrian Covaci & Robin E. Dodson. (2022) Per-and polyfluoroalkyl substances (PFAS) and persistent chemical mixtures in dust from U.S. colleges. Environmental Research 206, pages 112530.
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Yan Zhao, Kechen Fan, Yan Zhu, Yongbo Zhao, Jing Cai & Liping Jin. (2022) Gestational exposure to BDE-209 induces placental injury via the endoplasmic reticulum stress-mediated PERK/ATF4/CHOP signaling pathway. Ecotoxicology and Environmental Safety 233, pages 113307.
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Hao Chen, Rhianna Carty, Adrienne Bautista, Keri Hayakawa & Pamela Lein. (2022) Triiodothyronine or Antioxidants Block the Inhibitory Effects of BDE-47 and BDE-49 on Axonal Growth in Rat Hippocampal Neuron-Glia Co-Cultures. Toxics 10:2, pages 92.
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Ciming Lin, Zhijun Zeng, Ruibin Xu, Wanting Liang, Yufeng Guo & Xia Huo. (2022) Risk assessment of PBDEs and PCBs in dust from an e-waste recycling area of China. Science of The Total Environment 803, pages 150016.
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Chi-fong Ko, Yi-Chen Yang, Jennifer Ia Wen Wen Liu & Yang-hsin Shih. (2022) Thermal treatment of decabrominated diphenyl ether in its highly contaminated soil in Taiwan. Chemosphere 287, pages 131924.
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Elena V. Kozlova, Matthew C. Valdez, Maximillian E. Denys, Anthony E. Bishay, Julia M. Krum, Kayhon M. Rabbani, Valeria Carrillo, Gwendolyn M. Gonzalez, Gregory Lampel, Jasmin D. Tran, Brigitte M. Vazquez, Laura M. Anchondo, Syed A. Uddin, Nicole M. Huffman, Eduardo Monarrez, Duraan S. Olomi, Bhuvaneswari D. Chinthirla, Richard E. Hartman, Prasada Rao S. Kodavanti, Gladys Chompre, Allison L. Phillips, Heather M. Stapleton, Bernhard Henkelmann, Karl-Werner Schramm & Margarita C. Curras-Collazo. (2021) Persistent autism-relevant behavioral phenotype and social neuropeptide alterations in female mice offspring induced by maternal transfer of PBDE congeners in the commercial mixture DE-71. Archives of Toxicology 96:1, pages 335-365.
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Nor Zaiha Arman, Salmiati Salmiati, Azmi Aris, Mohd Razman Salim, Tasnia Hassan Nazifa, Mimi Suliza Muhamad & Marpongahtun Marpongahtun. (2021) A Review on Emerging Pollutants in the Water Environment: Existences, Health Effects and Treatment Processes. Water 13:22, pages 3258.
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Joe Jongpyo Lim, Moumita Dutta, Joseph L Dempsey, Hans-Joachim Lehmler, James MacDonald, Theo Bammler, Cheryl Walker, Terrance J Kavanagh, Haiwei Gu, Sridhar Mani & Julia Yue Cui. (2021) Neonatal Exposure to BPA, BDE-99, and PCB Produces Persistent Changes in Hepatic Transcriptome Associated With Gut Dysbiosis in Adult Mouse Livers. Toxicological Sciences 184:1, pages 83-103.
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Sagi Enicole A Gillera, William P Marinello, Kevin T Cao, Brian M Horman, Heather M Stapleton & Heather B Patisaul. (2021) Sex-specific Disruption of the Prairie Vole Hypothalamus by Developmental Exposure to a Flame Retardant Mixture. Endocrinology 162:8.
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Kathryn M. Rodgers, Deborah Bennett, Rebecca Moran, Kristin Knox, Tasha Stoiber, Ranjit Gill, Thomas M. Young, Arlene Blum & Robin E. Dodson. (2021) Do flame retardant concentrations change in dust after older upholstered furniture is replaced?. Environment International 153, pages 106513.
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Zixuan Liu, Qiushuang Zhu, Erqun Song & Yang Song. (2021) Polybrominated diphenyl ethers quinone exhibits neurotoxicity by inducing DNA damage, cell cycle arrest, apoptosis and p53-driven adaptive response in microglia BV2 cells. Toxicology 457, pages 152807.
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Quan-Bin Fu, Hai-Long Jiang, Lu-Qin Qiao, Xin Sun, Ming-Lin Wang & Ru-Song Zhao. (2020) Effective enrichment and detection of trace polybrominated diphenyl ethers in water samples based on magnetic covalent organic framework nanospheres coupled with chromatography-mass spectrometry. Journal of Chromatography A 1630, pages 461534.
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