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Potential protective roles of curcumin against cadmium-induced toxicity and oxidative stress

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Michelly Rodrigues Gonçalves, Vanessa Resende Nogueira Cruvinel, Steven Verpaele, Morteza Bashash, Carla Pintas Marques, Mariana Ragassi Urbano, Monica Maria Bastos Paoliello, Michael Aschner & Vivian da Silva Santos. (2024) Metal levels in waste pickers in Brasilia, Brazil: hair and nail as exposure matrices. Journal of Toxicology and Environmental Health, Part A 87:2, pages 77-90.
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Liana Martins de Oliveira, Luan Vitor Alves de Lima, Matheus Felipe da Silva, Ingrid Felicidade, Sandra Regina Lepri & Mário Sérgio Mantovani. (2023) Disruption of caspase-independent cell proliferation pathway on spheroids (HeLa cells) treated with curcumin. Journal of Toxicology and Environmental Health, Part A 86:22, pages 859-870.
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Wêndeo Kennedy Costa, Matheus Ferreira Do Nascimento, Valquíria Bruna Guimarães Silva, Bruno Vinicius Souza da Silva, Thiago Henrique Napoleão, Maria Tereza dos Santos Correia, Márcia Vanusa da Silva & Alisson Macário de Oliveira. (2023) Evaluation of 28-day repeated doses oral toxicity of essential oil from Psidium glaziovianum Kiaersk leaves on various biological parameters in Swiss mice. Journal of Toxicology and Environmental Health, Part A 86:19, pages 697-706.
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Tomokazu Ohishi, Sumio Hayakawa & Noriyuki Miyoshi. (2023) Involvement of microRNA modifications in anticancer effects of major polyphenols from green tea, coffee, wine, and curry. Critical Reviews in Food Science and Nutrition 63:24, pages 7148-7179.
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Sreevarsha Gali, Swati Sharma, Amit Kundu, Eunah Lee, Joo Hee Han, Joo Kyung Shin, Ji Soo Choi, So Young Kyung, Jae-Sung Kim & Hyung Sik Kim. (2023) Protective effect of dendropanoxide against cadmium-induced hepatotoxicity via anti-inflammatory activities in Sprague-Dawley rats. Toxicology Mechanisms and Methods 33:6, pages 437-451.
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Daiana Dalberto, Caroline Cardoso Nicolau, Melissa Rosa De Sousa, Ana Letícia Hilário Garcia, Fernanda Boaretto, Jaqueline Nascimento Picada, Guilherme Maurício Soares De Souza, Paola Chytry, Johnny Ferraz Dias, Cleverson Costa Feistel, Alexandre Barros Falcão Ferraz, Ivana Grivicich & Juliana Da Silva. (2021) Genotoxic effect induced by dried nicotiana tabacum leaves from tobacco barns (kiln-houses) in chinese hamster lung fibroblast cells (V79). Journal of Toxicology and Environmental Health, Part A 84:17, pages 689-701.
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Articles from other publishers (38)

Sara Hamdy, Gehad E. Elshopakey, Engy F. Risha, Shaymaa Rezk, Ahmed I. Ateya & Fatma M. Abdelhamid. (2024) Curcumin mitigates gentamicin induced-renal and cardiac toxicity via modulation of Keap1/Nrf2, NF-κB/iNOS and Bcl-2/BAX pathways. Food and Chemical Toxicology 183, pages 114323.
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Madrona Boutros & Sidhartha D Ray. 2024. Encyclopedia of Toxicology. Encyclopedia of Toxicology 221 230 .
Heba Nageh Gad El-Hak & Fatma Hashem Mohamed. (2023) Effect of lactoferrin supplement on cadmium chloride induced toxicity to male rats: Toxicopathological, ultrastructural and immunological studies. International Immunopharmacology 125, pages 111182.
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Hengtao Bu, Bao Wang, Yulin Wu, Pu Li, Yankang Cui, Xuping Jiang, Xiaowen Yu, Bianjiang Liu & Min Tang. (2023) Curcumin strengthens a spontaneous self-protective mechanism-SP1/PRDX6 pathway, against di-n-butyl phthalate-induced testicular ferroptosis damage. Environmental Science and Pollution Research.
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Mohamed Mohamed Soliman, Samy M. Sayed, Gehan Basiony Ahmed Youssef, Saed Athobaiti & Ahmed M. El-Shehawi. (2023) Taify Pomegranate Juice Extract Abrogates Testicular Dysfunction Induced by Acrylamide: Role of Inflammatory, Antioxidants, and Oxidative Stress Biomarkers. Andrologia 2023, pages 1-10.
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Ya Zhang, Mingjiang Liu & Ruijie Xie. (2023) Associations between cadmium exposure and whole-body aging: mediation analysis in the NHANES. BMC Public Health 23:1.
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Md. Niyaz Alam, Lubhan Singh, Najam Ali Khan, Yahya I. Asiri, Mohd. Zaheen Hassan, Obaid Afzal, Abdulmalik Saleh Alfawaz Altamimi & Md. Sarfaraj Hussain. (2023) Ameliorative Effect of Ethanolic Extract of Moringa oleifera Leaves in Combination with Curcumin against PTZ-Induced Kindled Epilepsy in Rats: In Vivo and In Silico. Pharmaceuticals 16:9, pages 1223.
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Dan Liang, Chang Liu & Mei Yang. (2023) Blood Cadmium and Abdominal Aortic Calcification in Population with Different Weight Statuses: a Population-Based Study. Journal of Cardiovascular Translational Research.
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Hasan Şimşek, Nurhan Akaras, Cihan Gür, Sefa Küçükler & Fatih Mehmet Kandemir. (2023) Beneficial effects of Chrysin on Cadmium‐induced nephrotoxicity in rats: Modulating the levels of Nrf2/HO‐1, RAGE/NLRP3, and Caspase-3/Bax/Bcl-2 signaling pathways. Gene 875, pages 147502.
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Muhammet Yusuf TEPEBAŞI & Perihan SEZGİNER. (2023) ANKAFERD BLOOD STOPPER ALLEVIATES CADMIUM-INDUCED LUNG INJURY BY REDUCING MITOCHONDRIAL STRESS-RELATED APOPTOSIS VIA BAX/BCL-2 AND CYT-C/CAS-3 PATHWAYSANKAFERD BLOOD STOPPER BAX/BCL-2 VE CYT-C/CAS-3 YOLAKLARI ARACILIĞIYLA MİTOKONDRİYAL STRESLE İLİŞKİLİ APOPTOZU AZALTARAK KADMİYUM KAYNAKLI AKCİĞER HASARINI HAFİFLETİR. SDÜ Tıp Fakültesi Dergisi 30:2, pages 225-233.
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Yinzhao Jia, Chuanzheng Yin, Wenbo Ke, Jing Liu, Bing Guo, Xiaofei Wang, Peng Zhao, Shaobo Hu, Chen Zhang, Xuan Li, Ran Liu, Xichuan Zheng, Yaofeng Wang, Gengqiao Wang, Hao Pan, Wenjun Hu & Zifang Song. (2023) Alpha-ketoglutarate alleviates cadmium-induced inflammation by inhibiting the HIF1A-TNFAIP3 pathway in hepatocytes. Science of The Total Environment 878, pages 163069.
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Adebiyi S. Adebayo, Ayodele P. Olufemi, Oluwaseyi Dasho, Damilola D. Awosika & Emmanuel Olagunju. (2023) Environmental impact assessment of active dumpsite in Ondo City, Nigeria: geochemical and geophysical approaches. Environmental Monitoring and Assessment 195:6.
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Dashuan Li, Chaolian Yang, Xiaomei Xu, Shanghang Li, Guofei Luo, Cheng Zhang, Zelan Wang, Dali Sun, Jianzhong Cheng & Qinghai Zhang. (2023) Low dosage fluorine ameliorates the bioaccumulation, hepatorenal dysfunction and oxidative stress, and gut microbiota perturbation of cadmium in rats. Environmental Pollution 324, pages 121375.
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Pei Wang, Lianguo Wang, Yilan Zhan, Yifan Liu, Ziqiang Chen, Jia Xu, Jun Guo, Jun Luo, Junchao Wei, Fei Tong & Zhihua Li. (2023) Versatile hybrid nanoplatforms for treating periodontitis with chemical/photothermal therapy and reactive oxygen species scavenging. Chemical Engineering Journal 463, pages 142293.
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Fatemeh Rajabian, Arezoo Rajabian & Zahra Tayarani-Najaran. (2023) The Antioxidant Activity of Betanin protects MRC-5 cells Against Cadmium Induced Toxicity. Biological Trace Element Research.
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Rohollah Ebrahimi, Mahdi Ebrahimi & Majid Shakeri. (2023) Mitigating the Adverse Effects of Lead and Cadmium Heavy Metals-Induced Oxidative Stress by Phytogenic Compounds in Poultry. Poultry 2:2, pages 235-251.
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Guangjin Gu, Jie Ren, Bin Zhu, Zhongju Shi, Shiqing Feng & Zhijian Wei. (2023) Multiple mechanisms of curcumin targeting spinal cord injury. Biomedicine & Pharmacotherapy 159, pages 114224.
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Qiao Liu, Mengzi Sun, Tong Wang, Yemian Zhou, Meng Sun, Han Li, Yun Liu & An Xu. (2023) The Differential Antagonistic Ability of Curcumin against Cytotoxicity and Genotoxicity Induced by Distinct Heavy Metals. Toxics 11:3, pages 233.
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Lina Jia, Tianwen Ma, Liangyu Lv, Yue Yu, Mingchao Zhao, Hong Chen & Li Gao. (2023) Endoplasmic reticulum stress mediated by ROS participates in cadmium exposure-induced MC3T3-E1 cell apoptosis. Ecotoxicology and Environmental Safety 251, pages 114517.
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Alieh Rezagholizade-shirvan, Mahboubeh Masrournia, Mohsen Fathi Najafi & Hossein Behmadi. (2022) Synthesis and characterization of nanoparticles based on chitosan-biopolymers systems as nanocarrier agents for curcumin: study on pharmaceutical and environmental applications. Polymer Bulletin 80:2, pages 1495-1517.
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Elena Smirnova, Mohammad Moniruzzaman, Sungyeon Chin, Anjana Sureshbabu, Adhimoolam Karthikeyan, Kyoungtag Do & Taesun Min. (2023) A Review of the Role of Curcumin in Metal Induced Toxicity. Antioxidants 12:2, pages 243.
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Lucas Fornari Laurindo, Gabriel Magno de Carvalho, Bárbara de Oliveira Zanuso, Maria Eduardo Figueira, Rosa Direito, Ricardo de Alvares Goulart, Daiene Santos Buglio & Sandra Maria Barbalho. (2023) Curcumin-Based Nanomedicines in the Treatment of Inflammatory and Immunomodulated Diseases: An Evidence-Based Comprehensive Review. Pharmaceutics 15:1, pages 229.
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Ilaria Ottonelli, Aruna Sharma, Barbara Ruozi, Giovanni Tosi, Jason Thomas Duskey, Maria Angela Vandelli, José Vicente Lafuente, Ala Nozari, Dafin Fior Muresanu, Anca Dana Buzoianu, Z. Ryan Tian, Zhiqiang Zhang, Cong Li, Lianyuan Feng, Lars Wiklund & Hari Shanker Sharma. 2023. Progress in Nanomedicine in Neurologic Diseases. Progress in Nanomedicine in Neurologic Diseases 385 416 .
Zarmin Iqbal, Ruhul Quds & Riaz Mahmood. (2022) Cadmium chloride generates cytotoxic reactive species that cause oxidative damage and morphological changes in human erythrocytes. Biochemistry and Cell Biology 100:6, pages 485-498.
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Adel G. Bakr, Emad H.M. Hassanein, Fares E.M. Ali & Ehab A.M. El-Shoura. (2022) Combined apocynin and carvedilol protect against cadmium-induced testicular damage via modulation of inflammatory response and redox-sensitive pathways. Life Sciences 311, pages 121152.
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Tianqi Ming, Qiu Tao, Shun Tang, Hui Zhao, Han Yang, Maolun Liu, Shan Ren & Haibo Xu. (2022) Curcumin: An epigenetic regulator and its application in cancer. Biomedicine & Pharmacotherapy 156, pages 113956.
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Amir Hossein Aalami, Mohammadsaleh Hoseinzadeh, Parsa Hosseini Manesh, Ali Jiryai Sharahi & Ehsan Kargar Aliabadi. (2022) Carcinogenic effects of heavy metals by inducing dysregulation of microRNAs: A review. Molecular Biology Reports 49:12, pages 12227-12238.
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Chunxiao Liu, Ruijie Zhang, Liu Yang, Tong Ji, Cuilan Zhu, Beibei Liu, Hai Zhang, Chong Xu, Nana Zhang, Shile Huang & Long Chen. (2022) Neuroprotection of resveratrol against cadmium-poisoning acts through dual inhibition of mTORC1/2 signaling. Neuropharmacology 219, pages 109236.
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Miroslava Požgajová, Alica Navrátilová & Marek Kovár. (2022) Curative Potential of Substances with Bioactive Properties to Alleviate Cd Toxicity: A Review. International Journal of Environmental Research and Public Health 19:19, pages 12380.
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Adebiyi S. Adebayo, Ayodele P. Olufemi, Lasun T. Ogundele, Omowunmi Q. Okunnuwa, Adekunle B. Toyeje & Christopher J. Olowookere. (2022) Ecological and human health risk assessments of metals in soil and tailing from Ife-Ijesha gold mining area, Southwest Nigeria. Environmental Earth Sciences 81:18.
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Xue-Wei Chen, Jia-Hong Chu, Lan-Xin Li, Pei-Chao Gao, Zhen-Yong Wang & Rui-Feng Fan. (2022) Protective mechanism of selenium on mercuric chloride-induced testis injury in chicken via p38 MAPK/ATF2/iNOS signaling pathway. Theriogenology 187, pages 188-194.
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Yasukiyo Yoshioka, Tomokazu Ohishi, Yoriyuki Nakamura, Ryuuta Fukutomi & Noriyuki Miyoshi. (2022) Anti-Cancer Effects of Dietary Polyphenols via ROS-Mediated Pathway with Their Modulation of MicroRNAs. Molecules 27:12, pages 3816.
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Chunyang Li, Dian Liu, Meigui Huang, Wuyang Huang, Ying Li & Jin Feng. (2022) Interfacial engineering strategy to improve the stabilizing effect of curcumin-loaded nanostructured lipid carriers. Food Hydrocolloids 127, pages 107552.
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Mehdi Firouzi, Maryam Ehteshamzadeh, Fakhredin Saba, Gholam Reza Khayati & Zhaleh Fakhri. (2022) Anti-Cancer Evaluation of Mineral Colloids Against MCF-7 Cell Lines: An Investigation Through Thermal Spring Water. Macromolecular Research 30:6, pages 406-414.
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Xueyan Hou, Jinying Liang, Xue Yang, Jintao Bai, Mingbo Yang, Ning Qiao, Zilong Hu, Xiqing Yan & Yongli Shi. (2022) Poloxamer188-based nanoparticles improve the anti-oxidation and anti-degradation of curcumin. Food Chemistry 375, pages 131674.
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Kerim Yesildag, Cihan Gur, Mustafa Ileriturk & Fatih Mehmet Kandemir. (2021) Evaluation of oxidative stress, inflammation, apoptosis, oxidative DNA damage and metalloproteinases in the lungs of rats treated with cadmium and carvacrol. Molecular Biology Reports 49:2, pages 1201-1211.
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Santa Cirmi, Alessandro Maugeri, Antonio Micali, Herbert Ryan Marini, Domenico Puzzolo, Giuseppe Santoro, Jose Freni, Francesco Squadrito, Natasha Irrera, Giovanni Pallio, Michele Navarra & Letteria Minutoli. (2021) Cadmium-Induced Kidney Injury in Mice Is Counteracted by a Flavonoid-Rich Extract of Bergamot Juice, Alone or in Association with Curcumin and Resveratrol, via the Enhancement of Different Defense Mechanisms. Biomedicines 9:12, pages 1797.
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S. S. Ostrovska, Yu. P. Myasoid, R. V. Kovtunenko, V. A. Myakushko, G. P. Chernenko, I. Y. Pismenetska & V. V. Baklunov. (2021) Effect of Cadmium on Children's Health in Prenatal and Postnatal Periods of Development. Ukraïnsʹkij žurnal medicini, bìologìï ta sportu 6:5, pages 414-422.
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