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Original Articles

The Discovery and Profile of FluconazoleFootnote

Pages 51-54 | Published online: 14 Jul 2016

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A. S. Garcia-Gomes, J. A. R. Curvelo, R. M. A Soares & A. Ferreira-Pereira. (2012) Curcumin acts synergistically with fluconazole to sensitize a clinical isolate of Candida albicans showing a MDR phenotype. Medical Mycology 50:1, pages 26-32.
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Alan J. Fischman, Nathaniel M. Alpert, John W. Babich & Robert H. Rubin. (1997) The Role of Positron Emission Tomography in Pharmacokinetic Analysis. Drug Metabolism Reviews 29:4, pages 923-956.
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Articles from other publishers (20)

Andreia Bento-Oliveira, Maria-Luísa C.J. Moita, Rodrigo F.M. de Almeida & Radosław Starosta. (2024) Unraveling environmental effects in the absorption and fluorescence spectra of p-methoxyphenylpiperazine derivatives. Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy 306, pages 123583.
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Wanying Wu, Tianqing Jiang, Haihui Lin, Chao Chen, Lingling Wang, Jikai Wen, Jun Wu & Yiqun Deng. (2023) The Specific Binding and Promotion Effect of Azoles on Human Aldo-Keto Reductase 7A2. Metabolites 13:5, pages 601.
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Jack D Sobel. (2023) New Antifungals for Vulvovaginal Candidiasis: What Is Their Role?. Clinical Infectious Diseases 76:5, pages 783-785.
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Pranay Wal, Nikita Saraswat & Himangi Vig. (2022) A Detailed Insight onto the Molecular and Cellular Mechanism of Action of the Antifungal Drugs Used in the Treatment of Superficial Fungal Infections. Current Drug Therapy 17:3, pages 148-159.
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Mohammad Shafiei, Lee Peyton, Mehrnoosh Hashemzadeh & Alireza Foroumadi. (2020) History of the development of antifungal azoles: A review on structures, SAR, and mechanism of action. Bioorganic Chemistry 104, pages 104240.
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Cristina de Castro Spadari, Fernanda Wirth, Luciana Biagini Lopes & Kelly Ishida. (2020) New Approaches for Cryptococcosis Treatment. Microorganisms 8:4, pages 613.
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Felix Bongomin, Rita O. Oladele, Sara Gago, Caroline B. Moore & Malcolm D. Richardson. (2018) A systematic review of fluconazole resistance in clinical isolates of Cryptococcus species . Mycoses 61:5, pages 290-297.
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Nermin H. Ibrahim, Nahla A. Melake, Ali M. Somily, Azza S. Zakaria, Manal M. Baddour & Amany Z. Mahmoud. (2015) The effect of antifungal combination on transcripts of a subset of drug-resistance genes in clinical isolates of Candida species induced biofilms. Saudi Pharmaceutical Journal 23:1, pages 55-66.
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Heleen Nailis, Davy Vandenbosch, Dieter Deforce, Hans J. Nelis & Tom Coenye. (2010) Transcriptional response to fluconazole and amphotericin B in Candida albicans biofilms. Research in Microbiology 161:4, pages 284-292.
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Sheng-Yuan Ruan & Po-Ren Hsueh. (2009) Invasive Candidiasis: An Overview from Taiwan. Journal of the Formosan Medical Association 108:6, pages 443-451.
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Yong Cui & Erica Yao. (2008) Evaluation of Hydrate-Screening Methods. Journal of Pharmaceutical Sciences 97:7, pages 2730-2744.
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C. Charlier, E. Hart, A. Lefort, P. Ribaud, F. Dromer, D. W. Denning & O. Lortholary. (2006) Fluconazole for the management of invasive candidiasis: where do we stand after 15 years?. Journal of Antimicrobial Chemotherapy 57:3, pages 384-410.
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Arthur Bentley, Michael Butters, Stuart P. Green, William J. Learmonth, Julie A. MacRae, Matthew C. Morland, Garry O'Conno & Joanne Skuse. (2002) The Discovery and Process Development of a Commercial Route to the Water Soluble Prodrug, Fosfluconazole. Organic Process Research & Development 6:2, pages 109-112.
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Alan J. Fischman, Nathaniel M. Alpert & Robert H. Rubin. (2002) Pharmacokinetic Imaging. Clinical Pharmacokinetics 41:8, pages 581-602.
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Eric O Aboagye, Patricia M Price & Terry Jones. (2001) In vivo pharmacokinetics and pharmacodynamics in drug development using positron-emission tomography. Drug Discovery Today 6:6, pages 293-302.
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Azeem Saleem, Eric O Aboagye & Patricia M Price. (2000) In vivo monitoring of drugs using radiotracer techniques. Advanced Drug Delivery Reviews 41:1, pages 21-39.
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Richard J. Hammes & John W. Babich. (2016) Positron Emission Tomography: Clinical Applications and Pharmaceutical Care. Journal of Pharmacy Practice 7:3, pages 124-139.
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A J FischmanN M AlpertE LivniS RayI SinclairR J CallahanJ A CorreiaD WebbH W StraussR H Rubin. (1993) Pharmacokinetics of 18F-labeled fluconazole in healthy human subjects by positron emission tomography. Antimicrobial Agents and Chemotherapy 37:6, pages 1270-1277.
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James W. Lee, Nita L. Seibel, Michael Amantea, Patricia Whitcomb, Philip A. Pizzo & Thomas J. Walsh. (1992) Safety and pharmacokinetics of fluconazole in children with neoplastic diseases. The Journal of Pediatrics 120:6, pages 987-993.
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E. Livni, Alan J. Fischman, Stephen Ray, Ian Sinclair, David R. Elmaleh, Nathaniel M. Alpert, Stephen Weiss, John A. Correia, Douglas Webb, Robert Dahl, William Robeson, Donald Margouleff, Robert Liss, H.William Strauss & Robert H. Rubin. (1992) Synthesis of 18F-labeled fluconazole and positron emission tomography studies in rabbits. International Journal of Radiation Applications and Instrumentation. Part B. Nuclear Medicine and Biology 19:2, pages 191-199.
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