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Antimicrobial Original Research Paper

Predicting effects of antibiotic combinations using MICs determined at pharmacokinetically derived concentration ratios: in vitro model studies with linezolid- and rifampicin-exposed Staphylococcus aureus

Maria V. GolikovaDepartment of Pharmacokinetics & Pharmacodynamics, Gause Institute of New Antibiotics, Moscow, Russia

http://orcid.org/0000-0002-7588-1733

Elena N. StrukovaDepartment of Pharmacokinetics & Pharmacodynamics, Gause Institute of New Antibiotics, Moscow, Russia

http://orcid.org/0000-0002-5391-1137

Yury A. PortnoyDepartment of Pharmacokinetics & Pharmacodynamics, Gause Institute of New Antibiotics, Moscow, Russia

Svetlana A. DovzhenkoDepartment of Pharmacokinetics & Pharmacodynamics, Gause Institute of New Antibiotics, Moscow, Russia

Mikhail B. KobrinDepartment of Pharmacokinetics & Pharmacodynamics, Gause Institute of New Antibiotics, Moscow, Russia

Stephen H. ZinnerDepartment of Medicine, Mount Auburn Hospital, Harvard Medical School, Cambridge, MA, USA

Alexander A. FirsovDepartment of Pharmacokinetics & Pharmacodynamics, Gause Institute of New Antibiotics, Moscow, RussiaCorrespondence[email protected]

http://orcid.org/0000-0001-7760-2729

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Citations (6)

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Maria V. Golikova, Kamilla N. Alieva, Alla V. Filimonova, Vladimir A. Ageevets, Ofeliia S. Sulian, Alisa A. Avdeeva, Sergey V. Sidorenko & Stephen H. Zinner. (2022) Klebsiella pneumoniae Susceptibility to Carbapenem/Relebactam Combinations: Influence of Inoculum Density and Carbapenem-to-Inhibitor Concentration Ratio. Biomedicines 10:6, pages 1454.
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Alla V. Filimonova, Maria V. Golikova, Elena N. Strukova, Yury A. Portnoy, Anastasiya A. Kuznetsova & Stephen H. Zinner. (2021) Predicting the Effects of Carbapenem/Carbapenemase Inhibitor Combinations against KPC-Producing Klebsiella pneumoniae in Time-Kill Experiments: Alternative versus Traditional Approaches to MIC Determination. Antibiotics 10:12, pages 1520.
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Lifang Jiang, Na Xie, Mingtao Chen, Yanyan Liu, Shuaishuai Wang, Jun Mao, Jiabin Li & Xiaohui Huang. (2021) Synergistic Combination of Linezolid and Fosfomycin Closing Each Other’s Mutant Selection Window to Prevent Enterococcal Resistance. Frontiers in Microbiology 11.
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Maria V. Golikova, Elena N. Strukova, Yury A. Portnoy, Stephen H. Zinner & Alexander A. Firsov. (2020) Verification of a Novel Approach to Predicting Effects of Antibiotic Combinations: In Vitro Dynamic Model Study with Daptomycin and Gentamicin against Staphylococcus aureus. Antibiotics 9:9, pages 538.
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Maria V. Golikova, Elena N. Strukova, Yury A. Portnoy, Stephen H. Zinner & Alexander A. Firsov. (2019) Predicting the antistaphylococcal effects of daptomycin–rifampicin combinations in an in vitro dynamic model. The Journal of Antibiotics 73:2, pages 101-107.
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Stephen H. Zinner, Maria V. Golikova, Elena N. Strukova, Yury A. Portnoy & Alexander A. Firsov. (2018) Predicting antibiotic combination effects on the selection of resistant Staphylococcus aureus: In vitro model studies with linezolid and gentamicin. International Journal of Antimicrobial Agents 52:6, pages 854-860.
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Predicting effects of antibiotic combinations using MICs determined at pharmacokinetically derived concentration ratios: in vitro model studies with linezolid- and rifampicin-exposed Staphylococcus aureus

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Predicting effects of antibiotic combinations using MICs determined at pharmacokinetically derived concentration ratios: in vitro model studies with linezolid- and rifampicin-exposed Staphylococcus aureus

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