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Amyloid
The Journal of Protein Folding Disorders
Volume 25, 2018 - Issue 3
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Original Article

A library of ATTR amyloidosis patient-specific induced pluripotent stem cells for disease modelling and in vitro testing of novel therapeutics

Richard M. GiadoneCenter for Regenerative Medicine, Boston University School of Medicine, Boston, MA, USA; View further author information
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Jessica D. RosardaDepartment of Molecular Medicine, The Scripps Research Institute, La Jolla, CA, USA; View further author information
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Prithvi Reddy AkepatiCenter for Regenerative Medicine, Boston University School of Medicine, Boston, MA, USA; View further author information
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Arianne C. ThomasCenter for Regenerative Medicine, Boston University School of Medicine, Boston, MA, USA; View further author information
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Batbold BoldbaatarAlan and Sandra Gerry Amyloid Research Laboratory, Amyloidosis Center, Boston University School of Medicine, Boston, MA, USA; View further author information
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Marianne F. JamesCenter for Regenerative Medicine, Boston University School of Medicine, Boston, MA, USA; View further author information
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Andrew A. WilsonCenter for Regenerative Medicine, Boston University School of Medicine, Boston, MA, USA; View further author information
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Vaishali SanchorawalaAmyloidosis Center, Boston University School of Medicine, Boston, MA, USA; ;Section of Hematology and Oncology, Department of Medicine, Boston University School of Medicine, Boston, MA, USAORCID Iconhttp://orcid.org/0000-0002-6307-2445View further author information
ORCID Icon,
Lawreen H. ConnorsAlan and Sandra Gerry Amyloid Research Laboratory, Amyloidosis Center, Boston University School of Medicine, Boston, MA, USA; View further author information
,
John L. BerkAmyloidosis Center, Boston University School of Medicine, Boston, MA, USA; ORCID Iconhttp://orcid.org/0000-0002-1768-2373View further author information
ORCID Icon,
R. Luke WisemanDepartment of Molecular Medicine, The Scripps Research Institute, La Jolla, CA, USA; View further author information
&
George J. MurphyCenter for Regenerative Medicine, Boston University School of Medicine, Boston, MA, USA; ;Section of Hematology and Oncology, Department of Medicine, Boston University School of Medicine, Boston, MA, USACorrespondence[email protected]
View further author information
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Pages 148-155 | Received 23 Mar 2018, Accepted 12 Jun 2018, Published online: 21 Jul 2018

Citations (10)

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Sabrina Ghosh, Carlos Villacorta-Martin, Jonathan Lindstrom-Vautrin, Devin Kenney, Carly S. Golden, Camille V. Edwards, Vaishali Sanchorawala, Lawreen H. Connors, Richard M. Giadone & George J. Murphy. (2023) Mapping cellular response to destabilized transthyretin reveals cell- and amyloidogenic protein-specific signatures. Amyloid 30:4, pages 379-393.
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Articles from other publishers (9)

Bernardo Bonilauri, Hye Sook Shin, Min Htet, Christopher D. Yan, Ronald M. Witteles, Karim Sallam & Joseph C. Wu. (2023) Generation of two induced pluripotent stem cell lines from patients with cardiac amyloidosis carrying heterozygous transthyretin (TTR) mutation. Stem Cell Research 72, pages 103215.
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Tarek Khedro, Jason M. Duran & Eric D. Adler. (2022) Modeling Nonischemic Genetic Cardiomyopathies Using Induced Pluripotent Stem Cells. Current Cardiology Reports 24:6, pages 631-644.
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Josef Blaszkiewicz & Stephen A. Duncan. (2022) Advancements in Disease Modeling and Drug Discovery Using iPSC-Derived Hepatocyte-like Cells. Genes 13:4, pages 573.
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Richard M. Giadone, Sabrina Ghosh & George J. Murphy. 2022. Novel Concepts in iPSC Disease Modeling. Novel Concepts in iPSC Disease Modeling 105 122 .
Alberto Posabella, Andrea B. Alber, Hendrik J. Undeutsch, Raoul A. Droeser, Anthony N. Hollenberg, Laertis Ikonomou & Darrell N. Kotton. (2021) Derivation of Thyroid Follicular Cells From Pluripotent Stem Cells: Insights From Development and Implications for Regenerative Medicine. Frontiers in Endocrinology 12.
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M. Teresa Donato, María Pelechá & Laia Tolosa. 2021. Recent Advances in iPSCs for Therapy, Volume 3. Recent Advances in iPSCs for Therapy, Volume 3 225 250 .
Richard M. Giadone, Derek C. Liberti, Taylor M. Matte, Jessica D. Rosarda, Celia Torres-Arancivia, Sabrina Ghosh, Jolene K. Diedrich, Sandra Pankow, Nicholas Skvir, J.C. Jean, John R. YatesIIIIII, Andrew A. Wilson, Lawreen H. Connors, Darrell N. Kotton, R. Luke Wiseman & George J. Murphy. (2020) Expression of Amyloidogenic Transthyretin Drives Hepatic Proteostasis Remodeling in an Induced Pluripotent Stem Cell Model of Systemic Amyloid Disease. Stem Cell Reports 15:2, pages 515-528.
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Joseph E. Kaserman, Killian Hurley, Mark Dodge, Carlos Villacorta-Martin, Marall Vedaie, Jyh-Chang Jean, Derek C. Liberti, Marianne F. James, Michelle I. Higgins, Nora J. Lee, George R. Washko, Raul San Jose Estepar, Jeffrey Teckman, Darrell N. Kotton & Andrew A. Wilson. (2020) A Highly Phenotyped Open Access Repository of Alpha-1 Antitrypsin Deficiency Pluripotent Stem Cells. Stem Cell Reports 15:1, pages 242-255.
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Ridwan Babatunde Ibrahim, Yo-Tsen Liu, Ssu-Yu Yeh & Jin-Wu Tsai. (2019) Contributions of Animal Models to the Mechanisms and Therapies of Transthyretin Amyloidosis. Frontiers in Physiology 10.
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