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Redox Report
Communications in Free Radical Research
Volume 3, 1997 - Issue 2
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Review Articles

Protein hydroperoxides as new reactive oxygen species

Pages 99-110 | Received 08 Apr 1997, Accepted 15 Apr 1997, Published online: 13 Jul 2016

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Adrián Aicardo, Mauricio Mastrogiovanni, Adriana Cassina & Rafael Radi. (2018) Propagation of free-radical reactions in concentrated protein solutions. Free Radical Research 52:2, pages 159-170.
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Janusz M. Gebicki. (2016) Electrons initiate efficient formation of hydroperoxides from cysteine. Free Radical Research 50:9, pages 987-996.
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Carole A. Firth, Ya-Ting Yang & Steven P. Gieseg. (2007) Lipid oxidation predominates over protein hydroperoxide formation in human monocyte-derived macrophages exposed to aqueous peroxyl radicals. Free Radical Research 41:7, pages 839-848.
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Aaron A. Platt & Steven P. Gieseg. (2003) Inhibition of protein hydroperoxide formation by protein thiols. Redox Report 8:2, pages 81-86.
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Steven P. Gieseg, Joseph Pearson & Carole A. Firth. (2003) Protein Hydroperoxides are a Major Product of Low Density Lipoprotein Oxidation During Copper, Peroxyl Radical and Macrophage-mediated Oxidation. Free Radical Research 37:9, pages 983-991.
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Silvia Gebicki, Katherine H. Gill, Roger T. Dean & Janusz M. Gebicki. (2002) Action of peroxidases on protein hydroperoxides. Redox Report 7:4, pages 235-242.
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S. Duggan, C. Rait, J.M. Gebicki & S.P. Gieseg. (2001) Inhibition of protein oxidation by the macrophage-synthesised antioxidant 7,8-dihydroneopterin. Redox Report 6:3, pages 188-190.
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J.M. Gebicki, J. Collins, C. Gay, S. Duggan & S. Gieseg. (2000) The dissection of oxidative changes in human blood serum and U937 cells exposed to free radicals. Redox Report 5:1, pages 55-56.
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Jesper F. Havelund, Katarzyna Wojdyla, Michael J. Davies, Ole N. Jensen, Ian Max M?ller & Adelina Rogowska-Wrzesinska. (2017) A biotin enrichment strategy identifies novel carbonylated amino acids in proteins from human plasma. Journal of Proteomics 156, pages 40-51.
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Janusz M. Gebicki. (2016) Oxidative stress, free radicals and protein peroxides. Archives of Biochemistry and Biophysics 595, pages 33-39.
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Anastasia S. Domazou, Janusz M. Gebicki, Thomas Nauser & Willem H. Koppenol. (2014) Repair of Protein Radicals by Antioxidants. Israel Journal of Chemistry 54:3, pages 254-264.
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Anastasia S. Domazou, Viviane Zelenay, Willem H. Koppenol & Janusz M. Gebicki. (2012) Efficient depletion of ascorbate by amino acid and protein radicals under oxidative stress. Free Radical Biology and Medicine 53:8, pages 1565-1573.
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Chia-Chi Liu & Janusz M. Gebicki. (2012) Intracellular GSH and ascorbate inhibit radical-induced protein chain peroxidation in HL-60 cells. Free Radical Biology and Medicine 52:2, pages 420-426.
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Philip E. Morgan, David I. Pattison & Michael J. Davies. (2012) Quantification of hydroxyl radical-derived oxidation products in peptides containing glycine, alanine, valine, and proline. Free Radical Biology and Medicine 52:2, pages 328-339.
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Morten R. Clausen, Kevin Huvaere, Leif H. Skibsted & Jan Stagsted. (2009) Characterization of Peroxides Formed by Riboflavin and Light Exposure of Milk. Detection of Urate Hydroperoxide as a Novel Oxidation Product. Journal of Agricultural and Food Chemistry 58:1, pages 481-487.
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Anastasia S. Domazou, Willem H. Koppenol & Janusz M. Gebicki. (2009) Efficient repair of protein radicals by ascorbate. Free Radical Biology and Medicine 46:8, pages 1049-1057.
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Magdalena A. Lam, David I. Pattison, Steven E. Bottle, Daniel J. Keddie & Michael J. Davies. (2008) Nitric Oxide and Nitroxides Can Act as Efficient Scavengers of Protein-Derived Free Radicals. Chemical Research in Toxicology 21:11, pages 2111-2119.
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Helen J. Tweeddale, Mari Kondo & Janusz M. Gebicki. (2007) Proteins protect lipid membranes from oxidation by thiyl radicals. Archives of Biochemistry and Biophysics 459:2, pages 151-158.
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Donkeun Park & Youling L. Xiong. (2007) Oxidative modification of amino acids in porcine myofibrillar protein isolates exposed to three oxidizing systems. Food Chemistry 103:2, pages 607-616.
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Kenji Fukuzawa, Aya Fujisaki, Kaori Akai, Akira Tokumura, Junji Terao & Janusz M. Gebicki. (2006) Measurement of phosphatidylcholine hydroperoxides in solution and in intact membranes by the ferric?xylenol orange assay. Analytical Biochemistry 359:1, pages 18-25.
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L. Distel, G. Schwotzer & H. Schüssler. (2006) Radiation-induced DNA double-strand breaks in dependence on protein concentration and under aerobic and anaerobic conditions. Radiation Physics and Chemistry 75:2, pages 210-217.
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Michael J. Davies. (2005) The oxidative environment and protein damage. Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics 1703:2, pages 93-109.
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Juan Du & Janusz M Gebicki. (2004) Proteins are major initial cell targets of hydroxyl free radicals. The International Journal of Biochemistry & Cell Biology 36:11, pages 2334-2343.
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Philip E Morgan, Roger T Dean & Michael J Davies. (2004) Protective mechanisms against peptide and protein peroxides generated by singlet oxygen. Free Radical Biology and Medicine 36:4, pages 484-496.
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Michael J. Davies. (2004) Reactive species formed on proteins exposed to singlet oxygen. Photochemical & Photobiological Sciences 3:1, pages 17-25.
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Craig A Gay & Janusz M Gebicki. (2003) Measurement of protein and lipid hydroperoxides in biological systems by the ferric?xylenol orange method. Analytical Biochemistry 315:1, pages 29-35.
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Henrietta A. Headlam & Michael J. Davies. (2003) Cell-mediated reduction of protein and peptide hydroperoxides to reactive free radicals. Free Radical Biology and Medicine 34:1, pages 44-55.
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Mark B Hampton, Philip E Morgan & Michael J Davies. (2002) Inactivation of cellular caspases by peptide-derived tryptophan and tyrosine peroxides. FEBS Letters 527:1-3, pages 289-292.
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Sean Duggan, Christopher Rait, Aaron Platt & Steven P Gieseg. (2002) Protein and thiol oxidation in cells exposed to peroxyl radicals is inhibited by the macrophage synthesised pterin 7,8-dihydroneopterin. Biochimica et Biophysica Acta (BBA) - Molecular Cell Research 1591:1-3, pages 139-145.
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Henrietta A. Headlam & Michael J. Davies. (2002) Beta-scission of side-chain alkoxyl radicals on peptides and proteins results in the loss of side-chains as aldehydes and ketones. Free Radical Biology and Medicine 32:11, pages 1171-1184.
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Philip E. Morgan, Roger T. Dean & Michael J. Davies. (2003) Inhibition of glyceraldehyde‐3‐phosphate dehydrogenase by peptide and protein peroxides generated by singlet oxygen attack. European Journal of Biochemistry 269:7, pages 1916-1925.
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S. A. Madison, J. E. B. McCallum & R. U. Rojas Wahl. (2002) Hydroperoxide formation in model collagens and collagen type I. International Journal of Cosmetic Science 24:1, pages 43-52.
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Clare L. Hawkins & Michael J. Davies. (2001) Generation and propagation of radical reactions on proteins. Biochimica et Biophysica Acta (BBA) - Bioenergetics 1504:2-3, pages 196-219.
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Jerzy W. Naskalski & Grzegorz Bartosz. 2001. Advances in Clinical Chemistry Volume 35. Advances in Clinical Chemistry Volume 35 161 253 .
MICHAEL J. DAVIES, SHANLIN FU, HONGJIE WANG & ROGER T. DEAN. 2001. Bio-Assays for Oxidative Stress Status. Bio-Assays for Oxidative Stress Status 17 29 .
Henrietta A. Headlam, Adam Mortimer, Christopher J. Easton & Michael J. Davies. (2000) β-Scission of C-3 (β-Carbon) Alkoxyl Radicals on Peptides and Proteins:  A Novel Pathway Which Results in the Formation of α-Carbon Radicals and the Loss of Amino Acid Side Chains. Chemical Research in Toxicology 13:11, pages 1087-1095.
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Isabelle Durot, Véronique Maupoil, Blandine Ponsard, Catherine Cordelet, Catherine Vergely-Vandriesse, Luc Rochette & Pierre Athias. (2000) Oxidative injury of isolated cardiomyocytes: dependence on free radical species. Free Radical Biology and Medicine 29:9, pages 846-857.
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Catherine Luxford, Roger T. Dean & Michael J. Davies. (2000) Radicals Derived from Histone Hydroperoxides Damage Nucleobases in RNA and DNA. Chemical Research in Toxicology 13:7, pages 665-672.
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Yongping Bao & Gary Williamson. 2000. Dietary Anticarcinogens and Antimutagens. Dietary Anticarcinogens and Antimutagens 245 248 .
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Michael J Davies, Shanlin Fu, Hongjie Wang & Roger T Dean. (1999) Stable markers of oxidant damage to proteins and their application in the study of human disease. Free Radical Biology and Medicine 27:11-12, pages 1151-1163.
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K. Sigler, J. Chaloupka, J. Brozmanová, N. Stadler & M. Höfer. (1999) Oxidative stress in microorganisms—I. Folia Microbiologica 44:6, pages 587-624.
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Craig Gay, James Collins & Janusz M. Gebicki. (1999) Hydroperoxide Assay with the Ferric?Xylenol Orange Complex. Analytical Biochemistry 273:2, pages 149-155.
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KENNETH B. BECKMAN & BRUCE N. AMES. (1998) The Free Radical Theory of Aging Matures. Physiological Reviews 78:2, pages 547-581.
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Julie A. Silvester, Graham S. Timmins & Michael J. Davies. (1998) Protein Hydroperoxides and Carbonyl Groups Generated by Porphyrin-Induced Photo-oxidation of Bovine Serum Albumin. Archives of Biochemistry and Biophysics 350:2, pages 249-258.
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