Publication Cover
Redox Report
Communications in Free Radical Research
Volume 3, 1997 - Issue 5-6
215
Views
57
CrossRef citations to date
0
Altmetric
Original Articles

Modification of red cell membrane lipids by hypochlorous acid and haemolysis by preformed lipid chlorohydrins

, , &
Pages 263-271 | Received 16 Oct 1997, Accepted 18 Dec 1997, Published online: 13 Jul 2016

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (4)

David I. Pattison, Michael J. Davies & Clare L. Hawkins. (2012) Reactions and reactivity of myeloperoxidase-derived oxidants: Differential biological effects of hypochlorous and hypothiocyanous acids. Free Radical Research 46:8, pages 975-995.
Read now
M.C.M. Vissers, A.C. Carr & C.C. Winterbourn. (2001) Fatty acid chlorohydrins and bromohydrins are cytotoxic to human endothelial cells. Redox Report 6:1, pages 49-56.
Read now

Articles from other publishers (53)

Rahmi Dianty, Junki Hirano, Itsuki Anzai, Yuta Kanai, Tsuyoshi Hayashi, Masae Morimoto, Chikako Kataoka-Nakamura, Sakura Kobayashi, Kentaro Uemura, Chikako Ono, Tokiko Watanabe, Takeshi Kobayashi, Kosuke Murakami, Kenji Kikuchi, Kunimoto Hotta, Toshikazu Yoshikawa, Shuhei Taguwa & Yoshiharu Matsuura. (2023) Electrolyzed hypochlorous acid water exhibits potent disinfectant activity against various viruses through irreversible protein aggregation. Frontiers in Microbiology 14.
Crossref
Luhong Wang, Yingying Zhou, Yong Dong Liu & Rugang Zhong. (2023) Computational Investigations of Reaction Mechanisms and Transformation Products of Olefins with Hypochlorous Acid. The Journal of Physical Chemistry A 127:24, pages 5129-5139.
Crossref
Gretchen Tibbits, Abdelrhman Mohamed, Suzanne Gelston, Laure Flurin, Yash S. Raval, Kerryl E. Greenwood‐Quaintance, Robin Patel & Haluk Beyenal. (2022) Activity of a hypochlorous acid‐producing electrochemical bandage as assessed with a porcine explant biofilm model. Biotechnology and Bioengineering 120:1, pages 250-259.
Crossref
Jeremy A. Snell, Jana Jandova & Georg T. Wondrak. (2022) Hypochlorous Acid: From Innate Immune Factor and Environmental Toxicant to Chemopreventive Agent Targeting Solar UV-Induced Skin Cancer. Frontiers in Oncology 12.
Crossref
Adam M.-A. Simpson, Min-Jeong Suh, Michael J. Plewa & William A. Mitch. (2021) Formation of Oleic Acid Chlorohydrins in Vegetables during Postharvest Chlorine Disinfection. Environmental Science & Technology 56:2, pages 1233-1243.
Crossref
Yohei Takeda, Sachiko Matsuda, Dulamjav Jamsransuren & Haruko Ogawa. (2021) Comparison of the SARS-CoV-2-inactivating activities of the differently manufactured hypochlorous acid water products with various pH. Journal of Water and Health 19:3, pages 448-456.
Crossref
Irfan Qadir Tantry, Asif Ali & Riaz Mahmood. (2021) Hypochlorous acid decreases antioxidant power, inhibits plasma membrane redox system and pathways of glucose metabolism in human red blood cells. Toxicology Research 10:2, pages 264-271.
Crossref
Karolina Starzak, Katarzyna Sutor, Tomasz Świergosz, Boris Nemzer, Zbigniew Pietrzkowski, Łukasz Popenda, Shi-Rong Liu, Shu-Pao Wu & Sławomir Wybraniec. (2021) The Responses of Bioactive Betanin Pigment and Its Derivatives from a Red Beetroot (Beta vulgaris L.) Betalain-Rich Extract to Hypochlorous Acid. International Journal of Molecular Sciences 22:3, pages 1155.
Crossref
Agnieszka Kumorkiewicz-Jamro, Karolina Starzak, Katarzyna Sutor, Boris Nemzer, Zbigniew Pietrzkowski, Łukasz Popenda & Sławomir Wybraniec. (2020) Structural Study on Hypochlorous Acid-Mediated Chlorination of Betanin and Its Decarboxylated Derivatives from an Anti-Inflammatory Beta vulgaris L. Extract. Molecules 25:2, pages 378.
Crossref
Karolina Starzak, Bernadette Creaven, Arkadiusz Matwijczuk, Alicja Matwijczuk & Dariusz Karcz. (2019) Anti-Hypochlorite and Catalytic Activity of Commercially Available Moringa oleifera Diet Supplement. Molecules 24:18, pages 3330.
Crossref
Kristian Wende, Thomas von Woedtke, Klaus-Dieter Weltmann & Sander Bekeschus. (2018) Chemistry and biochemistry of cold physical plasma derived reactive species in liquids. Biological Chemistry 400:1, pages 19-38.
Crossref
Mario Suwalsky, José Duguet & Hernán Speisky. (2017) An In Vitro Study of the Antioxidant and Antihemolytic Properties of Buddleja globosa (Matico). The Journal of Membrane Biology 250:3, pages 239-248.
Crossref
Jun Jacob Hu, Sen Ye & Dan Yang. (2017) Fluorescent Probes for HOCl Imaging. Israel Journal of Chemistry 57:3-4, pages 251-258.
Crossref
Mario Suwalsky, José Colina, María José Gallardo, Malgorzata Jemiola-Rzeminska, Kazimierz Strzalka, Marcela Manrique-Moreno & Benjamín Sepúlveda. (2016) Antioxidant Capacity of Gallic Acid in vitro Assayed on Human Erythrocytes. The Journal of Membrane Biology 249:6, pages 769-779.
Crossref
Mario Suwalsky, Patricia Ramírez, Marcia Avello, Fernando Villena, María José Gallardo, Andrés Barriga & Marcela Manrique-Moreno. (2016) Morphological Effects and Antioxidant Capacity of Solanum crispum (Natre) In Vitro Assayed on Human Erythrocytes. The Journal of Membrane Biology 249:3, pages 349-361.
Crossref
Yoji Kato. (2016) Neutrophil myeloperoxidase and its substrates: formation of specific markers and reactive compounds during inflammation. Journal of Clinical Biochemistry and Nutrition 58:2, pages 99-104.
Crossref
Jenny Schröter & Jürgen Schiller. (2016) Chlorinated Phospholipids and Fatty Acids: (Patho)physiological Relevance, Potential Toxicity, and Analysis of Lipid Chlorohydrins. Oxidative Medicine and Cellular Longevity 2016, pages 1-26.
Crossref
M. Suwalsky, M. Jemiola-Rzeminska, C. Astudillo, M.J. Gallardo, J.P. Staforelli, F. Villena & K. Strzalka. (2015) An in vitro study on the antioxidant capacity of usnic acid on human erythrocytes and molecular models of its membrane. Biochimica et Biophysica Acta (BBA) - Biomembranes 1848:11, pages 2829-2838.
Crossref
Samantha Jardon-Xicotencatl, Roberto Díaz-Torres, Alicia Marroquín-Cardona, Tania Villarreal-Barajas & Abraham Méndez-Albores. (2015) Detoxification of Aflatoxin-Contaminated Maize by Neutral Electrolyzed Oxidizing Water. Toxins 7:10, pages 4294-4314.
Crossref
Fiona H. GreigLisa HutchisonCorinne M. SpickettSimon Kennedy. (2015) Differential effects of chlorinated and oxidized phospholipids in vascular tissue: implications for neointima formation. Clinical Science 128:9, pages 579-592.
Crossref
M. Suwalsky, F.Villena & M.J. Gallardo. (2015) In vitro protective effects of resveratrol against oxidative damage in human erythrocytes. Biochimica et Biophysica Acta (BBA) - Biomembranes 1848:1, pages 76-82.
Crossref
Norsyahida Mohd Fauzi & Corinne M. Spickett. 2015. Studies on Experimental Toxicology and Pharmacology. Studies on Experimental Toxicology and Pharmacology 43 79 .
A. Mateu, L. Ramudo, M.A. Manso, D. Closa & I. De Dios. (2014) Acinar inflammatory response to lipid derivatives generated in necrotic fat during acute pancreatitis. Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease 1842:9, pages 1879-1886.
Crossref
Mario Suwalsky & Marcia Avello. (2014) Antioxidant Capacity of Ugni molinae Fruit Extract on Human Erythrocytes: An In Vitro Study. The Journal of Membrane Biology 247:8, pages 703-712.
Crossref
Sourav Panja, Dipankar Chaudhuri, Nikhil Baban Ghate, Ha Le Minh & Nripendranath Mandal. (2014) In vitro assessment of phytochemicals, antioxidant and DNA protective potential of wild edible fruit of Elaeagnus latifolia Linn. Fruits 69:4, pages 303-314.
Crossref
Benjamin S. Rayner, Dominic T. Love & Clare L. Hawkins. (2014) Comparative reactivity of myeloperoxidase-derived oxidants with mammalian cells. Free Radical Biology and Medicine 71, pages 240-255.
Crossref
Agnieszka Robaszkiewicz, Grzegorz Bartosz, Andrew R. Pitt, Alpesh Thakker, Richard A. Armstrong, Corinne M. Spickett & Mirosław Soszyński. (2014) HOCl-modified phosphatidylcholines induce apoptosis and redox imbalance in HUVEC-ST cells. Archives of Biochemistry and Biophysics 548, pages 1-10.
Crossref
Michael J. GrayWei-Yun WholeyUrsula Jakob. (2013) Bacterial Responses to Reactive Chlorine Species. Annual Review of Microbiology 67:1, pages 141-160.
Crossref
Neus Franco-Pons, Josefina Casas, Gemma Fabriàs, Sabrina Gea-Sorlí, Enrique de-Madaria, Emilio Gelpí & Daniel Closa. (2013) Fat Necrosis Generates Proinflammatory Halogenated Lipids During Acute Pancreatitis. Annals of Surgery 257:5, pages 943-951.
Crossref
Corinne M. SpickettNorsyahida Mohd Fauzi. (2011) Analysis of oxidized and chlorinated lipids by mass spectrometry and relevance to signalling. Biochemical Society Transactions 39:5, pages 1233-1239.
Crossref
Luigi Iuliano. (2011) Pathways of cholesterol oxidation via non-enzymatic mechanisms. Chemistry and Physics of Lipids 164:6, pages 457-468.
Crossref
I. V. Gorudko, T. V. Vakhrusheva, A. V. Mukhortova, S. N. Cherenkevich, A. V. Timoshenko, V. I. Sergienko & O. M. Panasenko. (2010) The priming effect of halogenated phospholipids on the functional responses of human neutrophils. Biochemistry (Moscow) Supplement Series A: Membrane and Cell Biology 4:3, pages 262-271.
Crossref
Agnieszka Robaszkiewicz, Fiona H. Greig, Andrew R. Pitt, Corinne M. Spickett, Grzegorz Bartosz & Mirosław Soszyński. (2010) Effect of phosphatidylcholine chlorohydrins on human erythrocytes. Chemistry and Physics of Lipids 163:7, pages 639-647.
Crossref
Michael J. DaviesClare L. HawkinsDavid I. PattisonMartin D. Rees. (2008) Mammalian Heme Peroxidases: From Molecular Mechanisms to Health Implications. Antioxidants & Redox Signaling 10:7, pages 1199-1234.
Crossref
M. C. Messner, C. J. Albert, J. McHowat & D. A. Ford. (2008) Identification of Lysophosphatidylcholine–Chlorohydrin in Human Atherosclerotic Lesions. Lipids 43:3, pages 243-249.
Crossref
Gary J. Dever, Robert Benson, Cherry L. Wainwright, Simon Kennedy & Corinne M. Spickett. (2008) Phospholipid chlorohydrin induces leukocyte adhesion to ApoE−/− mouse arteries via upregulation of P-selectin. Free Radical Biology and Medicine 44:3, pages 452-463.
Crossref
Ojia Skaff, David I. Pattison & Michael J. Davies. (2007) Kinetics of Hypobromous Acid-Mediated Oxidation of Lipid Components and Antioxidants. Chemical Research in Toxicology 20:12, pages 1980-1988.
Crossref
Corinne M. Spickett. (2007) Chlorinated lipids and fatty acids: An emerging role in pathology. Pharmacology & Therapeutics 115:3, pages 400-409.
Crossref
M. Suwalsky, P. Orellana, M. Avello & F. Villena. (2007) Protective effect of Ugni molinae Turcz against oxidative damage of human erythrocytes. Food and Chemical Toxicology 45:1, pages 130-135.
Crossref
Corinne M. Spickett & Gary Dever. (2005) Studies of phospholipid oxidation by electrospray mass spectrometry: From analysis in cells to biological effects. BioFactors 24:1-4, pages 17-31.
Crossref
Roberta De Sanctis, Roberta De Bellis, Carla Scesa, Umberto Mancini, Luigi Cucchiarini & Marina Dachà. (2008) In vitro protective effect of Rhodiola rosea extract against hypochlorous acid‐induced oxidative damage in human erythrocytes . BioFactors 20:3, pages 147-159.
Crossref
Gary Dever, Laura-Jayne Stewart, Andrew R Pitt & Corinne M Spickett. (2003) Phospholipid chlorohydrins cause ATP depletion and toxicity in human myeloid cells. FEBS Letters 540:1-3, pages 245-250.
Crossref
Carolyn J. Albert, Arun K. Thukkani, Rita M. Heuertz, Arne Slungaard, Stanley L. Hazen & David A. Ford. (2003) Eosinophil Peroxidase-derived Reactive Brominating Species Target the Vinyl Ether Bond of Plasmalogens Generating a Novel Chemoattractant, α-Bromo Fatty Aldehyde. Journal of Biological Chemistry 278:11, pages 8942-8950.
Crossref
Ben-Zhan Zhu, Anitra C Carr & Balz Frei. (2002) Pyrrolidine dithiocarbamate is a potent antioxidant against hypochlorous acid-induced protein damage. FEBS Letters 532:1-2, pages 80-84.
Crossref
Leu B Zavodnik, Ilya B Zavodnik, Elena A Lapshyna, Vjacheslav U Buko & Maria J Bryszewska. (2002) Hypochlorous acid-induced membrane pore formation in red blood cells. Bioelectrochemistry 58:2, pages 157-161.
Crossref
Ilya B. Zavodnik, Elena A. Lapshina, Lev B. Zavodnik, Mirosław Soszyński, Grzegorz Bartosz & Maria Bryszewska. (2002) Hypochlorous acid-induced oxidative damage of human red blood cells: effects of tert-butyl hydroperoxide and nitrite on the HOCl reaction with erythrocytes. Bioelectrochemistry 58:2, pages 127-135.
Crossref
Christine C. Winterbourn. (2002) Biological reactivity and biomarkers of the neutrophil oxidant, hypochlorous acid. Toxicology 181-182, pages 223-227.
Crossref
Mirosław Soszyński, Ilya B Zavodnik, Leu B Zavodnik, Ludmiła Żylinska, Grzegorz Bartosz & Maria Bryszewska. (2002) Hypochlorous acid inhibits glutathione S-conjugate export from human erythrocytes. Biochimica et Biophysica Acta (BBA) - Biomembranes 1564:2, pages 479-486.
Crossref
Clare L. Hawkins, Martin D. Rees & Michael J. Davies. (2002) Superoxide radicals can act synergistically with hypochlorite to induce damage to proteins. FEBS Letters 510:1-2, pages 41-44.
Crossref
Clare L. Hawkins, Bronwyn E. Brown & Michael J. Davies. (2001) Hypochlorite- and Hypobromite-Mediated Radical Formation and Its Role in Cell Lysis. Archives of Biochemistry and Biophysics 395:2, pages 137-145.
Crossref
Ilya B Zavodnik, Elena A Lapshina, Lev B Zavodnik, Grzegorz Bartosz, Miroslaw Soszynski & Maria Bryszewska. (2001) Hypochlorous acid damages erythrocyte membrane proteins and alters lipid bilayer structure and fluidity. Free Radical Biology and Medicine 30:4, pages 363-369.
Crossref
CHRISTINE C. WINTERBOURN & ANTHONY J. KETTLE. 2001. Bio-Assays for Oxidative Stress Status. Bio-Assays for Oxidative Stress Status 163 169 .
Christine C Winterbourn & Anthony J Kettle. (2000) Biomarkers of myeloperoxidase-derived hypochlorous acid. Free Radical Biology and Medicine 29:5, pages 403-409.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.