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Redox Report
Communications in Free Radical Research
Volume 22, 2017 - Issue 3
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Review Articles

Natural antioxidants in the treatment and prevention of diabetic nephropathy; a potential approach that warrants clinical trials

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David Polson, Nuria Villalba & Kalev Freeman. (2018) Optimization of a diagnostic platform for oxidation–reduction potential (ORP) measurement in human plasma. Redox Report 23:1, pages 125-129.
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Gloricel Serena-Romero, Anaís Ignot-Gutiérrez, Osvaldo Conde-Rivas, Marlenne Y. Lima-Silva, Armando J. Martínez, Daniel Guajardo-Flores & Elvia Cruz-Huerta. (2023) Impact of In Vitro Digestion on the Digestibility, Amino Acid Release, and Antioxidant Activity of Amaranth (Amaranthus cruentus L.) and Cañihua (Chenopodium pallidicaule Aellen) Proteins in Caco-2 and HepG2 Cells. Antioxidants 12:12, pages 2075.
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Jozaa Z. AlTamimi, Nora A. AlFaris, Ghedeir M. Alshammari, Reham I. Alagal, Dalal H. Aljabryn & Mohammed Abdo Yahya. (2023) Protective effect of eriodictyol against hyperglycemia-induced diabetic nephropathy in rats entails antioxidant and anti-inflammatory effects mediated by activating Nrf2. Saudi Pharmaceutical Journal 31:11, pages 101817.
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B. Candan, N. F. Karakuyu, K. Gülle, E. Sarman & D. Ulusoy Karatopuk. (2023) Beneficial Effects of Selenium on Kidney Injury via Nf-Kb and Aquaporin-1 Levels. Biological Trace Element Research.
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Hira Moin, Riffat Shafi, Ayesha Ishtiaq, Afrose Liaquat, Sadaf Majeed & Nilofar Nasir Zaidi. (2023) Effectiveness of analog of Humanin in ameliorating streptozotocin-induced diabetic nephropathy in Sprague Dawley rats. Peptides 165, pages 171014.
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Priya Chaudhary, Pracheta Janmeda, Anca Oana Docea, Balakyz Yeskaliyeva, Ahmad Faizal Abdull Razis, Babagana Modu, Daniela Calina & Javad Sharifi-Rad. (2023) Oxidative stress, free radicals and antioxidants: potential crosstalk in the pathophysiology of human diseases. Frontiers in Chemistry 11.
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Yujie Zhong, Lei Wang, Ruyi Jin, Jiayu Liu, Ruilin Luo, Yinghan Zhang, Lin Zhu & Xiaoli Peng. (2023) Diosgenin Inhibits ROS Generation by Modulating NOX4 and Mitochondrial Respiratory Chain and Suppresses Apoptosis in Diabetic Nephropathy. Nutrients 15:9, pages 2164.
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Feyzi Sinan Tokalı, Yeliz Demir, Cüneyt Türkeş, Büşra Dinçer & Şükrü Beydemir. (2023) Novel acetic acid derivatives containing quinazolin‐4(3 H )‐one ring: Synthesis, in vitro, and in silico evaluation of potent aldose reductase inhibitors . Drug Development Research 84:2, pages 275-295.
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Hassan Barakat, Ibrahim Ali Alkabeer, Sami A. Althwab, Hani A. Alfheeaid, Raghad M. Alhomaid, Mona S. Almujaydil, Raya S. A. Almuziree, Taqwa Bushnaq & Ahmed Mohamed. (2023) Nephroprotective Effect of Fennel (Foeniculum vulgare) Seeds and Their Sprouts on CCl4-Induced Nephrotoxicity and Oxidative Stress in Rats. Antioxidants 12:2, pages 325.
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María Dolores Rodriguez-Pérez, Laura Santiago-Corral, Laura Ortega-Hombrados, Cristina Verdugo, María Monsalud Arrebola, Esther Martín-Aurioles, María África Fernández-Prior, Alejandra Bermúdez-Oria, José Pedro De La Cruz & José Antonio González-Correa. (2023) The Effect of the Extra Virgin Olive Oil Minor Phenolic Compound 3′,4′-Dihydroxyphenylglycol in Experimental Diabetic Kidney Disease. Nutrients 15:2, pages 377.
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Yuting Sun, De Jin, Ziwei Zhang, Yuehong Zhang, Yuqing Zhang, Xiaomin Kang, Linlin Jiang, Xiaolin Tong & Fengmei Lian. (2023) Effects of antioxidants on diabetic kidney diseases: mechanistic interpretations and clinical assessment. Chinese Medicine 18:1.
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Xin Zhang, Qian Wang, Fagen Li, Suna Li, Hepu Lin & Yanhong Huo. (2023) Piceatannol Protects against High Glucose-Induced Injury of Renal Tubular Epithelial Cells via Regulating Carbonic Anhydrase 2. Nephron 147:8, pages 496-509.
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Daniela Maria Tanase, Evelina Maria Gosav, Madalina Ioana Anton, Mariana Floria, Petronela Nicoleta Seritean Isac, Loredana Liliana Hurjui, Claudia Cristina Tarniceriu, Claudia Florida Costea, Manuela Ciocoiu & Ciprian Rezus. (2022) Oxidative Stress and NRF2/KEAP1/ARE Pathway in Diabetic Kidney Disease (DKD): New Perspectives. Biomolecules 12:9, pages 1227.
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Marziyeh Salami, Raziyeh Salami, Alireza Mafi, Mohammad-Hossein Aarabi, Omid Vakili & Zatollah Asemi. (2022) Therapeutic Potential of Resveratrol in Diabetic Nephropathy According to Molecular Signaling. Current Molecular Pharmacology 15:5, pages 716-735.
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Hend F. Alharbi, Raya Algonaiman & Hassan Barakat. (2022) Ameliorative and Antioxidative Potential of Lactobacillus plantarum-Fermented Oat (Avena sativa) and Fermented Oat Supplemented with Sidr Honey against Streptozotocin-Induced Type 2 Diabetes in Rats. Antioxidants 11:6, pages 1122.
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H. Mbida, D. E. Tsala, S. Aboubakar, S. Habtemariam, J. J. Edmond, E. F. Bakwo & J. Z. Minkande. (2022) Antioxidant Activity of Aqueous Extract of Leaves and Seeds of Datura metel (Solanaceae) in Frog’s Heart Failure Model. Evidence-Based Complementary and Alternative Medicine 2022, pages 1-8.
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Syaifuzah Sapian, Siti Balkis Budin, Izatus Shima Taib, Vanitha Mariappan, Satirah Zainalabidin & Kok Yong Chin. (2022) Role of Polyphenol in Regulating Oxidative Stress, Inflammation, Fibrosis, and Apoptosis in Diabetic Nephropathy. Endocrine, Metabolic & Immune Disorders - Drug Targets 22:5, pages 453-470.
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Neeti Mehla, Aditi Kothari Chhajer, Kanishka Kumar, Shefali Dahiya & Vanshika Mohindroo. 2022. Plant Antioxidants and Health. Plant Antioxidants and Health 313 341 .
Milad Jeshan, Fatemeh Yousefbeyk, Hiva Rahmati, Amir Hosein Shoormeij, Mitra Rezazadeh & Ehsan Zamani. (2021) Salvia spinosa L. Protects against Diabetes-Induced Nephropathy by Attenuation of Mitochondrial Oxidative Damage in Mice. Advances in Pharmacological and Pharmaceutical Sciences 2021, pages 1-10.
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Qichao Hu, Caiyan Qu, Xiaolin Xiao, Wenwen Zhang, Yinxiao Jiang, Zhao Wu, Dan Song, Xi Peng, Xiao Ma & YanLing Zhao. (2021) Flavonoids on diabetic nephropathy: advances and therapeutic opportunities. Chinese Medicine 16:1.
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María Dolores Rodríguez-Pérez, Juan Antonio López-Villodres, María Monsalud Arrebola, Esther Martín-Aurioles, África Fernández-Prior, Alejandra Bermúdez-Oria, María Carmen Ríos, José Pedro De La Cruz & José Antonio González-Correa. (2021) Nephroprotective Effect of the Virgin Olive Oil Polyphenol Hydroxytyrosol in Type 1-like Experimental Diabetes Mellitus: Relationships with Its Antioxidant Effect. Antioxidants 10:11, pages 1783.
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Hailah M. ALmohaimeed, Zuhair M. Mohammedsaleh, Ashwaq H. Batawi, Maha Jameal Balgoon, Osama Ibrahim Ramadan, Hasan Ahmed Baz, Soad Al Jaouni & Nasra Naeim Ayuob. (2021) Synergistic Anti-inflammatory and Neuroprotective Effects of Cinnamomum cassia and Zingiber officinale Alleviate Diabetes-Induced Hippocampal Changes in Male Albino Rats: Structural and Molecular Evidence. Frontiers in Cell and Developmental Biology 9.
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Ayobami Dare, Mahendra L. Channa & Anand Nadar. (2021) L-ergothioneine and its combination with metformin attenuates renal dysfunction in type-2 diabetic rat model by activating Nrf2 antioxidant pathway. Biomedicine & Pharmacotherapy 141, pages 111921.
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Saima Selim, Noushin Akter, Shariful Islam Nayan, Faizul Islam Chowdhury, Nadia Saffoon, Ferdous Khan, Khondoker Shahin Ahmed, Md Iqbal Ahmed, Mohammad Maqsud Hossain & Md Ashraful Alam. (2021) Flacourtia indica fruit extract modulated antioxidant gene expression, prevented oxidative stress and ameliorated kidney dysfunction in isoprenaline administered rats. Biochemistry and Biophysics Reports 26, pages 101012.
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He Luan, Liu Ning, Zha Zheng-Xia, Liang Qing-hua, Liu Yan-Li & Xu Qiong-Ming. (2021) Anemoside B4 Alleviates the Development of Diabetic Nephropathy In Vitro and In Vivo. Revista Brasileira de Farmacognosia 31:3, pages 310-321.
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Sergey Sergeevich Popov, Elena Igorevna Anufrieva, Evgenii Dmitrievich Kryl’skii, Konstantin Konstantinovich Shulgin, Aleksey Nikolaevich Verevkin, Tatyana Nikolaevna Popova & Aleksander Nikolaevich Pashkov. (2021) The effect of methylethylpiridinol addition to the therapy on the level of pigment epithelium-derived factor and oxidative status in patients with diabetic nephropathy: randomized controlled open-label clinical study. Journal of Diabetes & Metabolic Disorders 20:1, pages 709-717.
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Guanglei Zuo, Hyun-Yong Kim, Yanymee N. Guillen Quispe, Zhiqiang Wang, Kang-Hyuk Kim, Paul H. Gonzales Arce & Soon-Sung Lim. (2021) Valeriana rigida Ruiz & Pav. Root Extract: A New Source of Caffeoylquinic Acids with Antioxidant and Aldose Reductase Inhibitory Activities. Foods 10:5, pages 1079.
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Nasra Ayuob, Mona Ramadan Al-Shathly, Abdulaziz Bakhshwin, Nouf Saeed Al-Abbas, Nehad A Shaer, Soad Al Jaouni & Walaa H. E. Hamed. (2021) p53 Rather Than β-Catenin Mediated the Combined Hypoglycemic Effect of Cinnamomum cassia (L.) and Zingiber officinale Roscoe in the Streptozotocin-Induced Diabetic Model. Frontiers in Pharmacology 12.
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Chunnuan Zhang, Junhui Wang, Qian Qi, Li Yang, Ping Sun & Xiaoyu Yuan. (2021) Modulatory effect of fructooligosaccharide against triphenyltin-induced oxidative stress and immune suppression in goldfish (Carassius auratus). Ecotoxicology and Environmental Safety 212, pages 111966.
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Ting-Ting Chang, Yi-An Chen, Szu-Yuan Li & Jaw-Wen Chen. (2021) Nrf-2 mediated heme oxygenase-1 activation contributes to the anti-inflammatory and renal protective effects of Ginkgo biloba extract in diabetic nephropathy. Journal of Ethnopharmacology 266, pages 113474.
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Omotayo O. Erejuwa, Daniel Ogbonna John Aja, Nkemjika I. Uwaezuoke, Kenneth I. Nwadike, Basil Chukwuma Ezeokpo, Joseph Linus Akpan, Nwobodo Ndubuisi Nwobodo, Ebisola Araromi & Ebere Asika. (2021) Effects of honey supplementation on renal dysfunction and metabolic acidosis in rats with high-fat diet-induced chronic kidney disease. Journal of Basic and Clinical Physiology and Pharmacology 32:1.
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Neeti Mehla, Aditi Kothari Chhajer, Kanishka Kumar, Shefali Dahiya & Vanshika Mohindroo. 2020. Plant Antioxidants and Health. Plant Antioxidants and Health 1 29 .
Xiaojun He, Zaian Deng, Wei Xu, Yahui Li, Chuchu Xu, Hong Chen & Jianliang Shen. (2020) A novel dual-response chemosensor for bioimaging of Exogenous/Endogenous hypochlorite and hydrazine in living cells, Pseudomonas aeruginosa and zebrafish. Sensors and Actuators B: Chemical 321, pages 128450.
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Yuexin Tian, Huifang Guo, Xinyan Miao, Jie Xu, Ran Yang, Lu Zhao, Jinxi Liu, Lin Yang, Fan Gao, Wei Zhang, Qingjuan Liu, Shaoguang Sun, Yu Tian, Hongbo Li, Jie Huang, Cunyang Gu, Shuxia Liu & Xiaojuan Feng. (2020) Nestin protects podocyte from injury in lupus nephritis by mitophagy and oxidative stress. Cell Death & Disease 11:5.
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Teresa Herrera, Amaia Iriondo-DeHond, Jaime Uribarri & María Dolores del Castillo. 2020. Nutrition, Fitness, and Mindfulness. Nutrition, Fitness, and Mindfulness 65 85 .
Chang Yang, Qi Feng, Huan Liao, Xinlei Yu, Yang Liu & Di Wang. (2019) Anti-Diabetic Nephropathy Activities of Polysaccharides Obtained from Termitornyces albuminosus via Regulation of NF-κB Signaling in db/db Mice. International Journal of Molecular Sciences 20:20, pages 5205.
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Yabing Xiong & Lili Zhou. (2019) The Signaling of Cellular Senescence in Diabetic Nephropathy. Oxidative Medicine and Cellular Longevity 2019, pages 1-16.
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Amany M. Hegazy, Eman M. El-Sayed, Khadiga S. Ibrahim & Amal S. Abdel-Azeem. (2019) Dietary antioxidant for disease prevention corroborated by the Nrf2 pathway. Journal of Complementary and Integrative Medicine 16:3.
Crossref
Gur P. Kaushal, Kiran Chandrashekar & Luis A. Juncos. (2019) Molecular Interactions Between Reactive Oxygen Species and Autophagy in Kidney Disease. International Journal of Molecular Sciences 20:15, pages 3791.
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Fuzhe Ma, Junduo Wu, Ziping Jiang, Wenlin Huang, Ye Jia, Weixia Sun & Hao Wu. (2019) P53/NRF2 mediates SIRT1's protective effect on diabetic nephropathy. Biochimica et Biophysica Acta (BBA) - Molecular Cell Research 1866:8, pages 1272-1281.
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Jingzhi Chang, Yuanting Zhou, Guobin Cong, Hui Guo, Yali Guo, Kun Lu, Yi chuan Li & Hua Tian. (2019) Dendrobium candidum protects against diabetic kidney lesions through regulating vascular endothelial growth factor, Glucose Transporter 1, and connective tissue growth factor expression in rats . Journal of Cellular Biochemistry 120:8, pages 13924-13931.
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Huan-Wei Chen, Mon-Yuan Yang, Tung-Wei Hung, Yun-Ching Chang & Chau-Jong Wang. (2019) Nelumbo nucifera leaves extract attenuate the pathological progression of diabetic nephropathy in high-fat diet-fed and streptozotocin-induced diabetic rats. Journal of Food and Drug Analysis 27:3, pages 736-748.
Crossref
Samsu U. Nurdin, Devi Sabarina, Subeki Subeki & Sussi Astuti. (2019) Antidiabetic and Antioxidant Activities of Bay, Pandan, Citrus Leaves and Their Combination in Vitro. Biomedical and Pharmacology Journal 12:2, pages 833-841.
Crossref
Zi-Jun Yang, Hong-Ru Wang, Yu-Iin Wang, Zi-Han Zhai, Liu-Wei Wang, Liang Li, Cheng Zhang & Lin Tang. (2019) Myricetin Attenuated Diabetes-Associated Kidney Injuries and Dysfunction via Regulating Nuclear Factor (Erythroid Derived 2)-Like 2 and Nuclear Factor-κB Signaling. Frontiers in Pharmacology 10.
Crossref
Xiaohong Wang, Aiqiong Qin, Fang Xiao, Opeyemi J. Olatunji, Shuyuan Zhang, Dong Pan, Weizhe Han, Daoqing Wang & Yihong Ni. (2019) N 6 -(2-hydroxyethyl)-adenosine from Cordyceps cicadae protects against diabetic kidney disease via alleviation of oxidative stress and inflammation . Journal of Food Biochemistry 43:2, pages e12727.
Crossref
Na Huang, Xuan Zhang, Youzhao Jiang, Hao Mei, Ling Zhang, Qiong Zhang, Jiongyu Hu & Bing Chen. (2018) Increased levels of serum pigment epithelium-derived factor aggravate proteinuria via induction of podocyte actin rearrangement. International Urology and Nephrology 51:2, pages 359-367.
Crossref
Isabel Nguyen, Arianne van Koppen & Jaap A. Joles. 2019. Diabetic Nephropathy. Diabetic Nephropathy 375 413 .
Manuel Matzinger, Katrin Fischhuber & Elke H. Heiss. (2018) Activation of Nrf2 signaling by natural products-can it alleviate diabetes?. Biotechnology Advances 36:6, pages 1738-1767.
Crossref
Yanning Li, Xiaoping Li, Kunyu He, Bin Li, Kun Liu, Jinsheng Qi, Hui Wang, Yu Wang & Weigang Luo. (2018) C‐peptide prevents NF‐κB from recruiting p300 and binding to the inos promoter in diabetic nephropathy . The FASEB Journal 32:4, pages 2269-2279.
Crossref

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