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Redox Report
Communications in Free Radical Research
Volume 24, 2019 - Issue 1
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Research Articles

Resveratrol improves osteogenic differentiation of senescent bone mesenchymal stem cells through inhibiting endogenous reactive oxygen species production via AMPK activation

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Elaheh Dalir Abdolahinia, Zahra Safari, Sayed Soroush Sadat Kachouei, Ramin Zabeti Jahromi, Nastaran Atashkar, Amirreza Karbalaeihasanesfahani, Mahdieh Alipour, Nastaran Hashemzadeh, Simin Sharifi & Solmaz Maleki Dizaj. (2022) Cell homing strategy as a promising approach to the vitality of pulp-dentin complexes in endodontic therapy: focus on potential biomaterials. Expert Opinion on Biological Therapy 22:11, pages 1405-1416.
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Hai-Yan Xue, Ming-Wei Liu & Guang Yang. (2023) Resveratrol suppresses lipopolysaccharide-mediated activation of osteoclast precursor RAW 264.7 cells by increasing miR-181a-5p expression. International Journal of Immunopathology and Pharmacology 37, pages 039463202311549.
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Yingyi Zhang, Xinfeng Yu, Chengcong Zhou, Keqi Fu, Huan Luo & Chengliang Wu. (2023) Targeting cellular senescence in senile osteoporosis: therapeutic potential of traditional Chinese medicine. Frontiers in Medicine 10.
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Cristina Mas-Bargues. (2023) Mitochondria pleiotropism in stem cell senescence: Mechanisms and therapeutic approaches. Free Radical Biology and Medicine 208, pages 657-671.
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Cong Ma, Ronghui Yu, Junhong Li, Jiashuo Chao & Ping Liu. (2023) Targeting proteostasis network in osteoporosis: Pathological mechanisms and therapeutic implications. Ageing Research Reviews 90, pages 102024.
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Mamuka Baramiya & Sergiy Mykhalskiy. (2023) From geroprotective tactics to anti-ageing strategy: ways to eliminate ageing per se. Ageing & Longevity:2 2023, pages 35-44.
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Ching-Lien Fang, Bin Liu & Mei Wan. (2023) “Bone-SASP” in Skeletal Aging. Calcified Tissue International 113:1, pages 68-82.
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Kexin Zhang, Xinzhe Du, Yao Gao, Sha Liu & Yong Xu. (2023) Mesenchymal Stem Cells for Treating Alzheimer’s Disease: Cell Therapy and Chemical Reagent Pretreatment. Journal of Alzheimer's Disease 93:3, pages 863-878.
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Qi Zhang, Sijing Hu, Jianjun Wu, Peng Sun, Quanlong Zhang, Yang Wang, Qiming Zhao, Ting Han, Luping Qin & Qiaoyan Zhang. (2023) Nystose attenuates bone loss and promotes BMSCs differentiation to osteoblasts through BMP and Wnt/β-catenin pathway in ovariectomized mice. Food Science and Human Wellness 12:2, pages 634-646.
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Hussein F. Sakr, Boudaka Ammar, Amira AlKharusi, I. Al-Lawati, Mahmoud AlKhateeb & Basim H. Elesawy. (2022) Resveratrol Modulates Bone Mineral Density and Bone Mineral Content in A Rat Model of Male Hypogonadism. Chinese Journal of Integrative Medicine 29:2, pages 146-154.
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Tsung-Jung Ho, Jung-Hsing Lin, Shinn Zong Lin, Wan-Ting Tsai, Jia-Ru Wu & Hao-Ping Chen. (2023) Isolation, Identification, and Characterization of Bioactive Peptides in Human Bone Cells from Tortoiseshell and Deer Antler Gelatin. International Journal of Molecular Sciences 24:2, pages 1759.
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Jin-Ho Park, Eun-Byeol Koh, Young-Jin Seo, Hye-Seong Oh, Ju-Yeong Won, Sun-Chul Hwang & June-Ho Byun. (2022) Tiron Has Negative Effects on Osteogenic Differentiation via Mitochondrial Dysfunction in Human Periosteum-Derived Cells. International Journal of Molecular Sciences 23:22, pages 14040.
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Lixian Zhao, Juan Xu, Song Li, Boyue Li, Muyun Jia, Baoxing Pang & Hao Cui. (2022) Resveratrol alleviates salivary gland dysfunction induced by ovariectomy in rats. Biochemical and Biophysical Research Communications 630, pages 112-117.
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Yanjie Yang, Tong Lei, Wangyu Bi, Zhuangzhuang Xiao, Xiaoshuang Zhang & Hongwu Du. (2022) The combined therapy of mesenchymal stem cell transplantation and resveratrol for diabetes: Future applications and challenges. Life Sciences 301, pages 120563.
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Zhongxu Chen, Yixin Wu, Qinlu Lin, Jie Cai, Xi Liu & Ying Liang. (2022) Nutrition Interventions of Herbal Compounds on Cellular Senescence. Oxidative Medicine and Cellular Longevity 2022, pages 1-17.
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Junhao Yin, Zhanglong Zheng, Xiaoli Zeng, Yijie Zhao, Zexin Ai, Miao Yu, Yang’ou Wu, Jirui Jiang, Jia Li & Shengjiao Li. (2022) lncRNA MALAT1 mediates osteogenic differentiation of bone mesenchymal stem cells by sponging miR-129-5p. PeerJ 10, pages e13355.
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Bowen Li, Mei Wang, Yuhua Liu, Yongsheng Zhou, Lin Tang, Pengyue You & Yi Deng. (2022) Independent effects of structural optimization and resveratrol functionalization on extracellular matrix scaffolds for bone regeneration. Colloids and Surfaces B: Biointerfaces 212, pages 112370.
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M.C. Echave, I. Erezuma, N. Golafshan, M. Castilho, F.B. Kadumudi, C. Pimenta-Lopes, F. Ventura, A. Pujol, J.J. Jimenez, J.A. Camara, R. Hernáez-Moya, L. Iturriaga, L. Sáenz Del Burgo, I. Iloro, M. Azkargorta, F. Elortza, R. Lakshminarayanan, T.H. Al-Tel, P. García-García, R. Reyes, A. Delgado, C. Évora, J.L. Pedraz, A. Dolatshahi-Pirouz & G. Orive. (2022) Bioinspired gelatin/bioceramic composites loaded with bone morphogenetic protein-2 (BMP-2) promote osteoporotic bone repair. Biomaterials Advances 134, pages 112539.
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Rong You, Lu Shi, Surong Chen, Qingpeng Liu, Lingkun Zhang, Liang Yin, Runcai Yang & Yan‐Qing Guan. (2021) Fabrication of Resveratrol‐Loaded Scaffolds and Their Application for Delaying Cell Senescence In Vitro. Macromolecular Bioscience 22:3, pages 2100440.
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Gurinder SINGH. (2022) Resveratrol Delivery <i>via</i> Gene Therapy: Entering the Modern Era. Turkish Journal of Pharmaceutical Sciences 19:1, pages 104-109.
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Guiwen Shi, Chaohua Yang, Qing Wang, Song Wang, Gaoju Wang, Rongguang Ao & Dejian Li. (2022) Traditional Chinese Medicine Compound-Loaded Materials in Bone Regeneration. Frontiers in Bioengineering and Biotechnology 10.
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Adrian Emilian Bădilă, Dragos Mihai Rădulescu, Andrei Ilie, Adelina-Gabriela Niculescu, Alexandru Mihai Grumezescu & Adrian Radu Rădulescu. (2022) Bone Regeneration and Oxidative Stress: An Updated Overview. Antioxidants 11:2, pages 318.
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Yasser El Miedany. 2022. New Horizons in Osteoporosis Management. New Horizons in Osteoporosis Management 491 524 .
Rohit Sharma. (2021) Bioactive food components for managing cellular senescence in aging and disease: A critical appraisal and perspectives. PharmaNutrition 18, pages 100281.
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Rui Yang, Yurong Yan, Zheng Wu, Yong Wei, Hao Song, Lian Zhu, Chenchen Zhao, Na Xu, Jijiang Fu & Kaifu Huo. (2021) Resveratrol-loaded titania nanotube coatings promote osteogenesis and inhibit inflammation through reducing the reactive oxygen species production via regulation of NF-κB signaling pathway. Materials Science and Engineering: C 131, pages 112513.
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Basem H. Elesawy, Hussein F. Sakr & Amr M. Abbas. (2021) Synergistic Protective Effects of Resveratrol and Estradiol on Estrogen Deficiency-Induced Osteoporosis Through Attenuating RANK Pathway. International Journal of Pharmacology 17:4, pages 217-228.
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Svetlana V. Kostyuk, Elena V. Proskurnina, Elizaveta S. Ershova, Larisa V. Kameneva, Elena M. Malinovskaya, Ekaterina A. Savinova, Vasilina A. Sergeeva, Pavel E. Umriukhin, Olga A. Dolgikh, Ekaterina A. Khakina, Olga A. Kraevaya, Pavel A. Troshin, Sergey I. Kutsev & Natalia N. Veiko. (2021) The Phosphonate Derivative of C60 Fullerene Induces Differentiation towards the Myogenic Lineage in Human Adipose-Derived Mesenchymal Stem Cells. International Journal of Molecular Sciences 22:17, pages 9284.
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Bangguo Wei, Wenrui Wang, Xiangyu Liu, Chenxi Xu, Yanan Wang, Ziqi Wang, Jinnuo Xu, Jianzhong Guan, Pinghui Zhou & Yingji Mao. (2021) Gelatin methacrylate hydrogel scaffold carrying resveratrol-loaded solid lipid nanoparticles for enhancement of osteogenic differentiation of BMSCs and effective bone regeneration. Regenerative Biomaterials 8:5.
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Yi‐Fan Guo, Tian Su, Mi Yang, Chang‐jun Li, Qi Guo, Ye Xiao, Yan Huang, Ya Liu & Xiang‐Hang Luo. (2021) The role of autophagy in bone homeostasis. Journal of Cellular Physiology 236:6, pages 4152-4173.
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Tung‐Sheng Chen, Shou‐Ying Chuang, Chia‐Yao Shen, Tsung‐Jung Ho, Ruey‐Lin Chang, Yu‐Lan Yeh, Chia‐Hua Kuo, B. Mahalakshmi, Wei‐Wen Kuo & Chih‐Yang Huang. (2021) Antioxidant Sirt1/Akt axis expression in resveratrol pretreated adipose‐derived stem cells increases regenerative capability in a rat model with cardiomyopathy induced by diabetes mellitus. Journal of Cellular Physiology 236:6, pages 4290-4302.
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Limei Li, Mali Yu, Yao Li, Qing Li, Hongcai Yang, Meng Zheng, Yi Han, Di Lu, Sheng Lu & Li Gui. (2021) Synergistic anti-inflammatory and osteogenic n-HA/resveratrol/chitosan composite microspheres for osteoporotic bone regeneration. Bioactive Materials 6:5, pages 1255-1266.
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Min Yin, Yan Zhang, Haibo Yu & Xia Li. (2021) Role of Hyperglycemia in the Senescence of Mesenchymal Stem Cells. Frontiers in Cell and Developmental Biology 9.
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Jilong Zou, Jianyang Du, Hualei Tu, Hongjun Chen, Kai Cong, Zhenggang Bi & Jiabing Sun. (2021) Resveratrol benefits the lineage commitment of bone marrow mesenchymal stem cells into osteoblasts via miR‐320c by targeting Runx2. Journal of Tissue Engineering and Regenerative Medicine 15:4, pages 347-360.
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Mengdi Yu, Hongxia Zhang, Brian Wang, Yinuo Zhang, Xiaoying Zheng, Bei Shao, Qichuan Zhuge & Kunlin Jin. (2021) Key Signaling Pathways in Aging and Potential Interventions for Healthy Aging. Cells 10:3, pages 660.
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Irene L. Tan & Michael C. Velarde. (2021) Targeting Mitochondria as a Strategy to Inhibit Cellular Senescence. Current Molecular Biology Reports 7:2, pages 20-29.
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Jie Wang, Lin Liu, Zhongjie Ding, Qing Luo, Yang Ju & Guanbin Song. (2021) Exogenous NAD+ Postpones the D-Gal-Induced Senescence of Bone Marrow-Derived Mesenchymal Stem Cells via Sirt1 Signaling. Antioxidants 10:2, pages 254.
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Oliver Pieles, Maria Hartmann & Christian Morsczeck. (2021) AMP-activated protein kinase and the down-stream activated process of autophagy regulate the osteogenic differentiation of human dental follicle cells. Archives of Oral Biology 122, pages 104951.
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Qiwen Wang, Yadong Qi, Weiyi Shen, Jilei Xu, Lan Wang, Shujie Chen, Tongyao Hou & Jianmin Si. (2021) The Aged Intestine: Performance and Rejuvenation. Aging and disease 12:7, pages 1693.
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Wang Ruolan, Chen Liangjiao & Shao Longquan. (2020) The mTOR/ULK1 signaling pathway mediates the autophagy-promoting and osteogenic effects of dicalcium silicate nanoparticles. Journal of Nanobiotechnology 18:1.
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Provvidenza M. Abruzzo, Silvia Canaider, Valeria Pizzuti, Luca Pampanella, Raffaella Casadei, Federica Facchin & Carlo Ventura. (2020) Herb-Derived Products: Natural Tools to Delay and Counteract Stem Cell Senescence. Stem Cells International 2020, pages 1-28.
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Kevin Spehar, Andrew Pan & Isabel Beerman. (2020) Restoring aged stem cell functionality: Current progress and future directions. Stem Cells 38:9, pages 1060-1077.
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Thomas Jansen, Miroslava Kvandová, Andreas Daiber, Paul Stamm, Katie Frenis, Eberhard Schulz, Thomas Münzel & Swenja Kröller-Schön. (2020) The AMP-Activated Protein Kinase Plays a Role in Antioxidant Defense and Regulation of Vascular Inflammation. Antioxidants 9:6, pages 525.
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Yixuan Jiang, Wenqiong Luo, Bin Wang, Xinyu Wang, Ping Gong & Yi Xiong. (2020) Resveratrol promotes osteogenesis via activating SIRT1/FoxO1 pathway in osteoporosis mice. Life Sciences 246, pages 117422.
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Xinxin Wang, Junwei Wu, Shanshan Ma, Ya Xie, Hongtao Liu, Minghao Yao, Yanting Zhang, Greta Luyuan Yang, Bo Yang, Ruixia Guo & Fangxia Guan. (2020) Resveratrol Preincubation Enhances the Therapeutic Efficacy of hUC-MSCs by Improving Cell Migration and Modulating Neuroinflammation Mediated by MAPK Signaling in a Mouse Model of Alzheimer’s Disease. Frontiers in Cellular Neuroscience 14.
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Abdul Qadir, Shujing Liang, Zixiang Wu, Zhihao Chen, Lifang Hu & Airong Qian. (2020) Senile Osteoporosis: The Involvement of Differentiation and Senescence of Bone Marrow Stromal Cells. International Journal of Molecular Sciences 21:1, pages 349.
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Fei Xing, Lang Li, Changchun Zhou, Cheng Long, Lina Wu, Haoyuan Lei, Qingquan Kong, Yujiang Fan, Zhou Xiang & Xingdong Zhang. (2019) Regulation and Directing Stem Cell Fate by Tissue Engineering Functional Microenvironments: Scaffold Physical and Chemical Cues. Stem Cells International 2019, pages 1-16.
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