Citations (29)
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Carolin Jaworski, Petar Iliev, Carmen Wängler, Björn Wängler, Brent Page, Ralf Schirrmacher & Justin J. Bailey. (2023) Type I inhibitors of tropomyosin receptor kinase (Trk): a 2020–2022 patent update. Expert Opinion on Therapeutic Patents 33:7-8, pages 503-521.
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Justin J. Bailey, Carolin Jaworski, Donovan Tung, Carmen Wängler, Björn Wängler & Ralf Schirrmacher. (2020) Tropomyosin receptor kinase inhibitors: an updated patent review for 2016–2019. Expert Opinion on Therapeutic Patents 30:5, pages 325-339.
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Jian Zou, Zhang Zhang, Fang Xu, Shengyang Cui, Chunli Qi, Jinfeng Luo, Zhen Wang, Xiaoyun Lu, Zhengchao Tu, Xiaomei Ren, Liyan Song & Ke Ding. (2019) GZD2202, a novel TrkB inhibitor, suppresses BDNF-mediated proliferation and metastasis in neuroblastoma models. Journal of Drug Targeting 27:4, pages 442-450.
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Amit Kumar Halder, Ana S. Moura & M. Natalia D. S. Cordeiro. (2018) QSAR modelling: a therapeutic patent review 2010-present. Expert Opinion on Therapeutic Patents 28:6, pages 467-476.
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Justin J. Bailey, Ralf Schirrmacher, Kristen Farrell & Vadim Bernard-Gauthier. (2017) Tropomyosin receptor kinase inhibitors: an updated patent review for 2010-2016 – Part II. Expert Opinion on Therapeutic Patents 27:7, pages 831-849.
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Articles from other publishers (22)
Qiaohua Qin, Qinglin Fu, Xin Wang, Ruicheng Lv, Shuyu Lu, Zhiqiang Guo, Tianxiao Wu, Yin Sun, Yixiang Sun, Nian Liu, Dongmei Zhao & Maosheng Cheng. (2023) Design, synthesis and biological evaluation of novel indolin-2-one derivatives as potent second-generation TRKs inhibitors. European Journal of Medicinal Chemistry, pages 115291.
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Yi Gong, Feng-Xu Wu, Ming-Shu Wang, Hong-Chuang Xu, Lin-Sheng Zhuo, Guang-Fu Yang & Wei Huang. (2022) Discovery of 3-pyrazolyl-substituted pyrazolo[1,5-a]pyrimidine derivatives as potent TRK inhibitors to overcome clinically acquired resistance. European Journal of Medicinal Chemistry 241, pages 114654.
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Shulei Pan, Liting Zhang, Xinling Luo, Jinshan Nan, Wei Yang, Huachao Bin, Yang Li, Qiao Huang, Tianqi Wang, Zhiling Pan, Bo Mu, Falu Wang, Chenyu Tian, Yang Liu, Linli Li & Shengyong Yang. (2022)
Structural Optimization and Structure–Activity Relationship Studies of 6,6-Dimethyl-4-(phenylamino)-6
H
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b
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H
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Hanna Cho, Namkyoung Kim, Takashi Murakami & Taebo Sim. (2021) Anti-Tumor Activity of AZD4547 Against NTRK1 Fusion Positive Cancer Cells Through Inhibition of NTRKs. Frontiers in Oncology 11.
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Mu-Chun Li, Wen-Hsing Lin, Pei-Chen Wang, Yu-Chieh Su, Pei-Yi Chen, Chu-Min Fan, Ching-Ping Chen, Chen-Lung Huang, Chun-Hsien Chiu, Ling Chang, Chiung-Tong Chen, Teng-Kuang Yeh & Hsing-Pang Hsieh. (2021) Design and synthesis of novel orally selective and type II pan-TRK inhibitors to overcome mutations by property-driven optimization. European Journal of Medicinal Chemistry 224, pages 113673.
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Ralf Schirrmacher, Vadim Bernard-Gauthier, Carolin Jaworski, Carmen Wängler, Björn Wängler & Justin Bailey. 2021. PET and SPECT of Neurobiological Systems. PET and SPECT of Neurobiological Systems
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Yunxin Duan, Jie Wang, Sihua Zhu, Zheng-Chao Tu, Zhang Zhang, Shingpan Chan & Ke Ding. (2020) Design, synthesis, and Structure–Activity Relationships (SAR) of 3-vinylindazole derivatives as new selective tropomyosin receptor kinases (Trk) inhibitors. European Journal of Medicinal Chemistry 203, pages 112552.
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Xiaoyun Lu, Jeff B. Smaill & Ke Ding. (2020) New Promise and Opportunities for Allosteric Kinase Inhibitors. Angewandte Chemie International Edition 59:33, pages 13764-13776.
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Xiaoyun Lu, Jeff B. Smaill & Ke Ding. (2020) Allosterische Kinaseinhibitoren – Erwartungen und Chancen. Angewandte Chemie 132:33, pages 13868-13881.
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Natasha M. Sosanya, Raina Kumar, John L. Clifford, Roger Chavez, George Dimitrov, Seshamalini Srinivasan, Aarti Gautam, Alex V. Trevino, Molly Williams, Rasha Hammamieh, Bopaiah P. Cheppudira, Robert J. Christy & Stephen L. Crimmins. (2020) Identifying Plasma Derived Extracellular Vesicle (EV) Contained Biomarkers in the Development of Chronic Neuropathic Pain. The Journal of Pain 21:1-2, pages 82-96.
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Noritaka Furuya, Takaki Momose, Kenji Katsuno, Nobuhiko Fushimi, Hideyuki Muranaka, Chiaki Handa, Masaaki Sawa, Tomonaga Ozawa & Takayoshi Kinoshita. (2020) An isoform-selective inhibitor of tropomyosin receptor kinase A behaves as molecular glue. Bioorganic & Medicinal Chemistry Letters 30:1, pages 126775.
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Juliana Kern de Moraes, Vivian Petersen Wagner, Felipe Paiva Fonseca, Gleyson Kleber do Amaral‐Silva, Caroline Brunetto de Farias, Emily Ferreira Salles Pilar, Lauro Gregianin, Rafael Roesler, Pablo Agustin Vargas & Manoela Domingues Martins. (2019) Activation of BDNF/TrkB/Akt pathway is associated with aggressiveness and unfavorable survival in oral squamous cell carcinoma. Oral Diseases 25:8, pages 1925-1936.
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Shengyang Cui, Yongjin Wang, Yuting Wang, Xia Tang, Xiaomei Ren, Lei Zhang, Yong Xu, Zhang Zhang, Zhi-Min Zhang, Xiaoyun Lu & Ke Ding. (2019) Design, synthesis and biological evaluation of 3-(imidazo[1,2-a]pyrazin-3-ylethynyl)-2-methylbenzamides as potent and selective pan-tropomyosin receptor kinase (TRK) inhibitors. European Journal of Medicinal Chemistry 179, pages 470-482.
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Qi Miao, Kun Ma, Dong Chen, Xiaoxing Wu & Sheng Jiang. (2019) Targeting tropomyosin receptor kinase for cancer therapy. European Journal of Medicinal Chemistry 175, pages 129-148.
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Wei Yan, Naga Rajiv Lakkaniga, Francesca Carlomagno, Massimo Santoro, Neil Q. McDonaldFengping Lv, Naresh Gunaganti, Brendan Frett & Hong-yu Li. (2018) Insights into Current Tropomyosin Receptor Kinase (TRK) Inhibitors: Development and Clinical Application. Journal of Medicinal Chemistry 62:4, pages 1731-1760.
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Igor A. Schepetkin, Andrei I. Khlebnikov, Andrei S. Potapov, Anastasia R. Kovrizhina, Vladislava V. Matveevskaya, Maxim L. Belyanin, Dmitriy N. Atochin, Svitlana O. Zanoza, Nadiya M. Gaidarzhy, Sergiy A. Lyakhov, Liliya N. Kirpotina & Mark T. Quinn. (2019) Synthesis, biological evaluation, and molecular modeling of 11H-indeno[1,2-b]quinoxalin-11-one derivatives and tryptanthrin-6-oxime as c-Jun N-terminal kinase inhibitors. European Journal of Medicinal Chemistry 161, pages 179-191.
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Kenji Nakano & Shunji Takahashi. (2018) Translocation-Related Sarcomas. International Journal of Molecular Sciences 19:12, pages 3784.
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Samo Turk, Benjamin Merget, Sameh Eid & Simone Fulle. (2018) From Cancer to Pain Target by Automated Selectivity Inversion of a Clinical Candidate. Journal of Medicinal Chemistry 61:11, pages 4851-4859.
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Kenji Nakano & Shunji Takahashi. (2018) Current Molecular Targeted Therapies for Bone and Soft Tissue Sarcomas. International Journal of Molecular Sciences 19:3, pages 739.
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Vadim Bernard-Gauthier, Andrew V. Mossine, Anne Mahringer, Arturo Aliaga, Justin J. Bailey, Xia Shao, Jenelle Stauff, Janna Arteaga, Phillip Sherman, Marilyn Grand’Maison, Pierre-Luc Rochon, Björn Wängler, Carmen Wängler, Peter Bartenstein, Alexey Kostikov, David R. Kaplan, Gert Fricker, Pedro Rosa-Neto, Peter J. H. Scott & Ralf Schirrmacher. (2018)
Identification of [
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Eder Ricardo de Moraes, Christopher Kushmerick & Lígia Araujo Naves. (2017) Morphological and functional diversity of first-order somatosensory neurons. Biophysical Reviews 9:5, pages 847-856.
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Vadim Bernard-Gauthier, Justin J. Bailey, Andrew V. Mossine, Simon Lindner, Lena Vomacka, Arturo Aliaga, Xia Shao, Carole A. Quesada, Phillip Sherman, Anne Mahringer, Alexey Kostikov, Marilyn Grand’Maison, Pedro Rosa-Neto, Jean-Paul Soucy, Alexander Thiel, David R. Kaplan, Gert Fricker, Björn Wängler, Peter Bartenstein, Ralf Schirrmacher & Peter J. H. Scott. (2017) A Kinome-Wide Selective Radiolabeled TrkB/C Inhibitor for in Vitro and in Vivo Neuroimaging: Synthesis, Preclinical Evaluation, and First-in-Human. Journal of Medicinal Chemistry 60:16, pages 6897-6910.
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