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Expert Opinion on Therapeutic Patents Volume 27, 2017 - Issue 11
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Review

Identification of spirocyclic or phosphate substituted quinolizine derivatives as novel HIV-1 integrase inhibitors: a patent evaluation of WO2016094197A1, WO2016094198A1 and WO2016154527A1

Xiqiang ChengDepartment of Medicinal Chemistry, Key Laboratory of Chemical Biology (Ministry of Education), School of Pharmaceutical Sciences, Shandong University, Jinan, Shandong, P. R. ChinaView further author information
,
Ping GaoDepartment of Medicinal Chemistry, Key Laboratory of Chemical Biology (Ministry of Education), School of Pharmaceutical Sciences, Shandong University, Jinan, Shandong, P. R. ChinaView further author information
,
Lin SunDepartment of Medicinal Chemistry, Key Laboratory of Chemical Biology (Ministry of Education), School of Pharmaceutical Sciences, Shandong University, Jinan, Shandong, P. R. ChinaView further author information
,
Ye TianDepartment of Medicinal Chemistry, Key Laboratory of Chemical Biology (Ministry of Education), School of Pharmaceutical Sciences, Shandong University, Jinan, Shandong, P. R. ChinaView further author information
,
Peng ZhanDepartment of Medicinal Chemistry, Key Laboratory of Chemical Biology (Ministry of Education), School of Pharmaceutical Sciences, Shandong University, Jinan, Shandong, P. R. ChinaCorrespondence[email protected]
View further author information
&
Xinyong LiuDepartment of Medicinal Chemistry, Key Laboratory of Chemical Biology (Ministry of Education), School of Pharmaceutical Sciences, Shandong University, Jinan, Shandong, P. R. ChinaCorrespondence[email protected]
View further author information
Pages 1277-1286 | Received 29 May 2017, Accepted 24 Jul 2017, Published online: 02 Aug 2017

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Yoshiyuki Taoda, Shuichi Sugiyama & Takahiro Seki. (2023) New designs for HIV-1 integrase inhibitors: a patent review (2018-present). Expert Opinion on Therapeutic Patents 33:1, pages 51-66.
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Xiaofang Zuo, Zhipeng Huo, Dongwei Kang, Gaochan Wu, Zhongxia Zhou, Xinyong Liu & Peng Zhan. (2018) Current insights into anti-HIV drug discovery and development: a review of recent patent literature (2014–2017). Expert Opinion on Therapeutic Patents 28:4, pages 299-316.
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Articles from other publishers (5)

Wulan Zeng, Xia Wang, Youwang Li, Xueao Li & Yuxing Zhang. (2022) Structural, spectroscopic and computational studies of two new spirocompounds containing 2,3,4-trimethoxybenzyl group. Journal of Molecular Structure 1269, pages 133806.
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Ilona K. Jóźwik, Dario O. Passos & Dmitry Lyumkis. (2020) Structural Biology of HIV Integrase Strand Transfer Inhibitors. Trends in Pharmacological Sciences 41:9, pages 611-626.
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Divyang M. Patel, Hetal J. Patel, José M. Padrón & Hitendra M. Patel. (2020) A novel substrate directed multicomponent reaction for the syntheses of tetrahydro-spiro[pyrazolo[4,3- f ]quinoline]-8,5′-pyrimidines and tetrahydro-pyrazolo[4,3- f ]pyrimido[4,5- b ]quinolines via selective multiple C–C bond formation under metal-free conditions . RSC Advances 10:33, pages 19600-19609.
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Divyang M. Patel & Hitendra M. Patel. (2019) Trimethylglycine-Betaine-Based-Catalyst-Promoted Novel and Ecocompatible Pseudo-Four-Component Reaction for Regioselective Synthesis of Functionalized 6,8-Dihydro-1′ H ,5 H -spiro[[1,3]dioxolo[4,5- g ]quinoline-7,5′-pyrimidine]-2′,4′,6′(3′ H )-trione Derivatives . ACS Sustainable Chemistry & Engineering 7:22, pages 18667-18676.
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Narges Pakravan, Hassan Shayani-Jam, Hadi Beiginejad, Hadis Tavafi & Shadi Paziresh. (2019) A green method for the synthesis of novel spiro compounds: Enhancement of antibacterial properties of caffeic acid through electrooxidation in the presence of barbituric acid derivatives. Journal of Electroanalytical Chemistry 848, pages 113286.
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