402
Views
13
CrossRef citations to date
0
Altmetric
Review

A patent update on PDK1 inhibitors (2015-present)

ORCID Icon & ORCID Icon
Pages 271-282 | Received 10 Jan 2019, Accepted 18 Mar 2019, Published online: 29 Mar 2019

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (2)

Kailasam N. Vennila & Kuppanagounder P. Elango. (2023) Insilico molecular modelling to identify PDK-1 targeting agents based on its protein–protein docking interaction. Journal of Biomolecular Structure and Dynamics 0:0, pages 1-12.
Read now
Pavel Klener. (2020) Mantle cell lymphoma: insights into therapeutic targets at the preclinical level. Expert Opinion on Therapeutic Targets 24:10, pages 1029-1045.
Read now

Articles from other publishers (11)

Nana Zheng, Jiaqi Wei, Depei Wu, Yang Xu & Jianping Guo. (2023) Master kinase PDK1 in tumorigenesis. Biochimica et Biophysica Acta (BBA) - Reviews on Cancer 1878:6, pages 188971.
Crossref
Garth Powis, Emmanuelle J. Meuillet, Martin Indarte, Garrett Booher & Lynn Kirkpatrick. (2023) Pleckstrin Homology [PH] domain, structure, mechanism, and contribution to human disease. Biomedicine & Pharmacotherapy 165, pages 115024.
Crossref
Antonino Glaviano, Aaron S. C. Foo, Hiu Y. Lam, Kenneth C. H. Yap, William Jacot, Robert H. Jones, Huiyan Eng, Madhumathy G. Nair, Pooyan Makvandi, Birgit Geoerger, Matthew H. Kulke, Richard D. Baird, Jyothi S. Prabhu, Daniela Carbone, Camilla Pecoraro, Daniel B. L. Teh, Gautam Sethi, Vincenzo Cavalieri, Kevin H. Lin, Nathalie R. Javidi-Sharifi, Eneda Toska, Matthew S. Davids, Jennifer R. Brown, Patrizia Diana, Justin Stebbing, David A. Fruman & Alan P. Kumar. (2023) PI3K/AKT/mTOR signaling transduction pathway and targeted therapies in cancer. Molecular Cancer 22:1.
Crossref
Maria Antonietta Occhiuzzi, Gernando Lico, Giuseppina Ioele, Michele De Luca, Antonio Garofalo & Fedora Grande. (2023) Recent advances in PI3K/PKB/mTOR inhibitors as new anticancer agents. European Journal of Medicinal Chemistry 246, pages 114971.
Crossref
Na Wang, Jianjiang Fu, Zhihua Li, Ningni Jiang, Yanhong Chen & Juan Peng. (2022) The Landscape of PDK1 in Breast Cancer. Cancers 14:3, pages 811.
Crossref
Lajpreet Kaur, Mallika Pathak, Siddhartha Dan, Rahul Singhal, Vinod Kumar & Himanshu Ojha. 2022. Protein Kinase Inhibitors. Protein Kinase Inhibitors 435 456 .
Eva Hitz, Natalie Wiedemar, Armin Passecker, Beatriz A. S. Graça, Christian Scheurer, Sergio Wittlin, Nicolas M. B. Brancucci, Ioannis Vakonakis, Pascal Mäser & Till S. Voss. (2021) The 3-phosphoinositide–dependent protein kinase 1 is an essential upstream activator of protein kinase A in malaria parasites. PLOS Biology 19:12, pages e3001483.
Crossref
Diancai Zhang, Yujie Wang, Guangzhi Li & Baoxiang Zhang. (2021) Tanshinone IIA alleviates vitiligo by suppressing AKT mediated CD8 +  T cells activation in a mouse model . Dermatologic Therapy 34:5.
Crossref
Jonathan Mitchel, Pratima Bajaj, Ketki Patil, Austin Gunnarson, Emilie Pourchet, Yoo Na Kim, Jeffrey Skolnick & S. Balakrishna Pai. (2021) Computational Identification of Stearic Acid as a Potential PDK1 Inhibitor and In Vitro Validation of Stearic Acid as Colon Cancer Therapeutic in Combination with 5-Fluorouracil. Cancer Informatics 20, pages 117693512110659.
Crossref
Xiaohua Zhang & Shan Zhong. (2020) PDK1 Inhibitor GSK-470 Exhibits Potent Anticancer Activity in a Pheochromocytoma PC12 Cell Tumor Model via Akt/mTOR Pathway. Anti-Cancer Agents in Medicinal Chemistry 20:7, pages 828-833.
Crossref
Ilaria Casari, Alice Domenichini, Simona Sestito, Emily Capone, Gianluca Sala, Simona Rapposelli & Marco Falasca. (2019) Dual PDK1/Aurora Kinase A Inhibitors Reduce Pancreatic Cancer Cell Proliferation and Colony Formation. Cancers 11:11, pages 1695.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.