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Expert Opinion on Therapeutic Patents Volume 30, 2020 - Issue 11
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Review

Inhibitors of type II transmembrane serine proteases in the treatment of diseases of the respiratory tract – A review of patent literature

Alexandre Murzaa Institut de Pharmacologie de Sherbrooke, Université de Sherbrooke, Sherbrooke (Québec), Canada;b Département de Pharmacologie-Physiologie, Faculté de Médecine et des Sciences de la Santé, Université de Sherbrooke, Sherbrooke (Québec), CanadaView further author information
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Sébastien P. Diona Institut de Pharmacologie de Sherbrooke, Université de Sherbrooke, Sherbrooke (Québec), Canada;b Département de Pharmacologie-Physiologie, Faculté de Médecine et des Sciences de la Santé, Université de Sherbrooke, Sherbrooke (Québec), CanadaView further author information
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Pierre-Luc Boudreaulta Institut de Pharmacologie de Sherbrooke, Université de Sherbrooke, Sherbrooke (Québec), Canada;b Département de Pharmacologie-Physiologie, Faculté de Médecine et des Sciences de la Santé, Université de Sherbrooke, Sherbrooke (Québec), CanadaView further author information
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Antoine Désiletsa Institut de Pharmacologie de Sherbrooke, Université de Sherbrooke, Sherbrooke (Québec), Canada;b Département de Pharmacologie-Physiologie, Faculté de Médecine et des Sciences de la Santé, Université de Sherbrooke, Sherbrooke (Québec), CanadaView further author information
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Richard Leduca Institut de Pharmacologie de Sherbrooke, Université de Sherbrooke, Sherbrooke (Québec), Canada;b Département de Pharmacologie-Physiologie, Faculté de Médecine et des Sciences de la Santé, Université de Sherbrooke, Sherbrooke (Québec), CanadaView further author information
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Éric Marsaulta Institut de Pharmacologie de Sherbrooke, Université de Sherbrooke, Sherbrooke (Québec), Canada;b Département de Pharmacologie-Physiologie, Faculté de Médecine et des Sciences de la Santé, Université de Sherbrooke, Sherbrooke (Québec), CanadaCorrespondence[email protected]
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Pages 807-824 | Received 11 Jun 2020, Accepted 25 Aug 2020, Published online: 12 Oct 2020

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Saman Zare Gheshlaghi, Ebrahim Nakhaei, Ali Ebrahimi, Majid Jafari, Asiyeh Shahraki, Shiva Rezazadeh, Erfan Saberinasab, Alireza Nowroozi & Seyede Samira Hosseini. (2023) Analysis of medicinal and therapeutic potential of Withania somnifera derivatives against COVID-19. Journal of Biomolecular Structure and Dynamics 41:14, pages 6883-6893.
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Articles from other publishers (15)

Wei Li, Huaman Wu & Juan Xu. (2023) Construction of a genomic instability-derived predictive prognostic signature for non-small cell lung cancer patients. Cancer Genetics 278-279, pages 24-37.
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Éloïc Colombo, Antoine Désilets, Malihe Hassanzadeh, Gabriel Lemieux, Isabelle Marois, Dominic Cliche, Julien A. Delbrouck, Alexandre Murza, François Jean, Eric Marsault, Martin V. Richter, Richard Leduc & Pierre‐Luc Boudreault. (2023) Optimization of Ketobenzothiazole‐Based Type II Transmembrane Serine Protease Inhibitors to Block H1N1 Influenza Virus Replication. ChemMedChem.
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Qingyu Wu, Shuo Li, Xianrui Zhang & Ningzheng Dong. (2023) Type II Transmembrane Serine Proteases as Modulators in Adipose Tissue Phenotype and Function. Biomedicines 11:7, pages 1794.
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Matthew T. J. Halma, Christof Plothe, Paul Marik & Theresa A. Lawrie. (2023) Strategies for the Management of Spike Protein-Related Pathology. Microorganisms 11:5, pages 1308.
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Semi Kim. (2023) TMPRSS4, a type II transmembrane serine protease, as a potential therapeutic target in cancer. Experimental & Molecular Medicine 55:4, pages 716-724.
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Wei ZhangZhenfa ChenTing WangXihua WangLing LiuWenbin Huang & Shufeng Li. (2023) Increased Expression of TMPRSS11E Is Involved in LPS- or Poly(I:C)-mediated Inflammation. American Journal of Respiratory Cell and Molecular Biology 68:4, pages 406-416.
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Shufeng Li, Zhenfa Chen, Wei Zhang, Ting Wang, Xihua Wang, Chao Wang, Jie Chao & Ling Liu. (2022) Elevated expression of the membrane-anchored serine protease TMPRSS11E in NSCLC progression. Carcinogenesis 43:11, pages 1092-1102.
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Mehdi Oubahmane, Ismail Hdoufane, Imane Bjij, Nouhaila Ait Lahcen, Didier Villemin, Rachid Daoud, Achraf El Allali & Driss Cherqaoui. (2022) Host Cell Proteases Mediating SARS-CoV-2 Entry: An Overview. Current Topics in Medicinal Chemistry 22:21, pages 1776-1792.
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Tirosh Shapira, I. Abrrey Monreal, Sébastien P. Dion, David W. Buchholz, Brian Imbiakha, Andrea D. Olmstead, Mason Jager, Antoine Désilets, Guang Gao, Mathias Martins, Thierry Vandal, Connor A. H. Thompson, Aaleigha Chin, William D. Rees, Theodore Steiner, Ivan Robert Nabi, Eric Marsault, Julie Sahler, Diego G. Diel, Gerlinde R. Van de Walle, Avery August, Gary R. Whittaker, Pierre-Luc Boudreault, Richard Leduc, Hector C. Aguilar & François Jean. (2022) A TMPRSS2 inhibitor acts as a pan-SARS-CoV-2 prophylactic and therapeutic. Nature 605:7909, pages 340-348.
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Kassandra T. Ávila-Alvarez, Mónica L. Chávez-González, Elda P. Segura-Ceniceros, José L. Martínez-Hernández, Roberto Arredondo-Valdes, Mayela Govea-Salas, Erika Nava-Reyna, Anna Ilyina & Rodolfo Ramos-González. 2022. Value-Addition in Food Products and Processing Through Enzyme Technology. Value-Addition in Food Products and Processing Through Enzyme Technology 413 425 .
Shuo Li, Lina Wang, Shijin Sun & Qingyu Wu. (2020) Hepsin: a multifunctional transmembrane serine protease in pathobiology. The FEBS Journal 288:18, pages 5252-5264.
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Mohd. Imran, Ahmed Subeh Alshrari, Syed Mohammed Basheeruddin Asdaq & Abida. (2021) Trends in the development of remdesivir based inventions against COVID-19 and other disorders: A patent review. Journal of Infection and Public Health 14:8, pages 1075-1086.
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Nabil G. Seidah, Antonella Pasquato & Ursula Andréo. (2021) How Do Enveloped Viruses Exploit the Secretory Proprotein Convertases to Regulate Infectivity and Spread?. Viruses 13:7, pages 1229.
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Philippe Sarret. (2021) Éric Marsault (1971–2021): A Legacy through the Prism of Relationship Chemistry. Journal of Medicinal Chemistry 64:9, pages 5221-5224.
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Jaehwan You, Jong Hyeon Seok, Myungsoo Joo, Joon-Yong Bae, Jin Il Kim, Man-Seong Park & Kisoon Kim. (2021) Multifactorial Traits of SARS-CoV-2 Cell Entry Related to Diverse Host Proteases and Proteins. Biomolecules & Therapeutics 29:3, pages 249-262.
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