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Expert Opinion on Investigational Drugs Volume 25, 2016 - Issue 12
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Editorial

Developments with investigational Janus kinase inhibitors for rheumatoid arthritis

Luca SemeranoInserm UMR 1125, Bobigny, France;Sorbonne Paris Cité, Université Paris 13, Bobigny, France;Department of Rheumatology, Hôpitaux Universitaires Paris-Seine-Saint Denis, Assistance-Publique-Hôpitaux de Paris (APHP), Bobigny, FranceView further author information
,
Patrice DeckerInserm UMR 1125, Bobigny, France;Sorbonne Paris Cité, Université Paris 13, Bobigny, FranceView further author information
,
Gaëlle ClavelSorbonne Paris Cité, Université Paris 13, Bobigny, France;Department of Internal Medicine, Fondation Rothschild, Paris, FranceView further author information
&
Marie-Christophe BoissierInserm UMR 1125, Bobigny, France;Sorbonne Paris Cité, Université Paris 13, Bobigny, France;Department of Rheumatology, Hôpitaux Universitaires Paris-Seine-Saint Denis, Assistance-Publique-Hôpitaux de Paris (APHP), Bobigny, FranceCorrespondence[email protected]
View further author information
Pages 1355-1359 | Received 26 Jun 2016, Accepted 13 Oct 2016, Published online: 31 Oct 2016

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Sowmya Andole, Gouthami Thumma, Rajasekhar Reddy Alavala & Kiran Gangarapu. (2023) Field-based 3D-QSAR for tyrosine protein kinase JAK-2 inhibitors. Journal of Biomolecular Structure and Dynamics 0:0, pages 1-13.
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Silvia Rosina, Gabriella Giancane & Nicolino Ruperto. (2022) Emerging therapies for juvenile arthritis: agents in early clinical trials. Expert Opinion on Investigational Drugs 31:10, pages 1109-1124.
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Lina Serhal & Christopher J. Edwards. (2019) Upadacitinib for the treatment of rheumatoid arthritis. Expert Review of Clinical Immunology 15:1, pages 13-25.
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Maria Gabriella Raimondo, Martina Biggioggero, Chiara Crotti, Andrea Becciolini & Ennio Giulio Favalli. (2017) Profile of sarilumab and its potential in the treatment of rheumatoid arthritis. Drug Design, Development and Therapy 11, pages 1593-1603.
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Gaëlle Clavel, Marie-Christophe Boissier, Johanna Sigaux & Luca Semerano. (2017) Developments with experimental and investigational drugs for axial spondyloarthritis. Expert Opinion on Investigational Drugs 26:7, pages 833-842.
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Articles from other publishers (14)

Rohitas Deshmukh. (2023) Rheumatoid arthritis: Pathophysiology, current therapeutic strategies and recent advances in targeted drug delivery system. Materials Today Communications 35, pages 105877.
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Pooja Mathur, Ravinder Verma, Manish Kumar, Vikas Jhawat, Rohit Dutt & Shailendra Bhatt. (2023) Current Remedial Strategies for the Treatment of Rheumatoid Arthritis through the Oral Route with Janus Kinase Inhibitors. Drug Delivery Letters 13:1, pages 13-23.
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Faping Wang, Xiaoju Tang, Min Zhu, Hui Mao, Huajing Wan & Fengming Luo. (2022) Efficacy and Safety of JAK Inhibitors for Rheumatoid Arthritis: A Meta-Analysis. Journal of Clinical Medicine 11:15, pages 4459.
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Anuja Singh, Tapan Behl, Aayush Sehgal, Sukhbir Singh, Neelam Sharma, Tanveer Naved, Saurabh Bhatia, Ahmed Al-Harrasi, Prasun Chakrabarti, Lotfi Aleya, Celia Vargas-De-La-Cruz & Simona Bungau. (2021) Mechanistic insights into the role of B cells in rheumatoid arthritis. International Immunopharmacology 99, pages 108078.
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Annika Reddig, Linda Voss, Karina Guttek, Dirk Roggenbuck, Eugen Feist & Dirk Reinhold. (2021) Impact of Different JAK Inhibitors and Methotrexate on Lymphocyte Proliferation and DNA Damage. Journal of Clinical Medicine 10:7, pages 1431.
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Wenxia LuoOlufola O. IgeTasnim H. BeaconRuey-Chyi SuShujun HuangJames R. DavieTed M. Lakowski. (2021) The treatment of SARS-CoV2 with antivirals and mitigation of the cytokine storm syndrome: the role of gene expression. Genome 64:4, pages 400-415.
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Marie-Christophe Boissier, Jérome Biton, Luca Semerano, Patrice Decker & Natacha Bessis. (2020) Origins of rheumatoid arthritis. Joint Bone Spine 87:4, pages 301-306.
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Marie-Christophe Boissier, Jérôme Biton, Luca Semerano, Patrice Decker & Natacha Bessis. (2019) L’origine de la polyarthrite rhumatoïde. Revue du Rhumatisme 86, pages A19-A24.
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Jack W. Singer, Suliman Al-Fayoumi, Jason Taylor, Sharlene Velichko & Alison O’Mahony. (2019) Comparative phenotypic profiling of the JAK2 inhibitors ruxolitinib, fedratinib, momelotinib, and pacritinib reveals distinct mechanistic signatures. PLOS ONE 14:9, pages e0222944.
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Hooi-Yeen Yap, Sabrina Tee, Magdelyn Wong, Sook-Khuan Chow, Suat-Cheng Peh & Sin-Yeang Teow. (2018) Pathogenic Role of Immune Cells in Rheumatoid Arthritis: Implications in Clinical Treatment and Biomarker Development. Cells 7:10, pages 161.
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Hisao Hamaguchi, Yasushi Amano, Ayako Moritomo, Shohei Shirakami, Yutaka Nakajima, Kazuo Nakai, Naoko Nomura, Misato Ito, Yasuyuki Higashi & Takayuki Inoue. (2018) Discovery and structural characterization of peficitinib (ASP015K) as a novel and potent JAK inhibitor. Bioorganic & Medicinal Chemistry 26:18, pages 4971-4983.
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Qiang Guo, Yuxiang Wang, Dan Xu, Johannes Nossent, Nathan J. Pavlos & Jiake Xu. (2018) Rheumatoid arthritis: pathological mechanisms and modern pharmacologic therapies. Bone Research 6:1.
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Ennio Giulio Favalli, Maria Gabriella Raimondo, Andrea Becciolini, Chiara Crotti, Martina Biggioggero & Roberto Caporali. (2017) The management of first-line biologic therapy failures in rheumatoid arthritis: Current practice and future perspectives. Autoimmunity Reviews 16:12, pages 1185-1195.
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Natacha Bessis, Patrice Decker, Eric Assier, Luca Semerano & Marie-Christophe Boissier. (2017) Arthritis models: usefulness and interpretation. Seminars in Immunopathology 39:4, pages 469-486.
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