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Expert Opinion on Investigational Drugs Volume 27, 2018 - Issue 12
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Drug Evaluation

CSL112, a reconstituted, infusible, plasma-derived apolipoprotein A-I: safety and tolerability profiles and implications for management in patients with myocardial infarction

Davide CapodannoDivision of Cardiology, CAST, P.O. “Rodolico”, Azienda Ospedaliero-Universitaria “Policlinico-Vittorio Emanuele”, University of Catania, Catania, ItalyView further author information
,
Roxana MehranColumbia University Medical Center and the Cardiovascular Research Foundation, New York, NY, USAView further author information
,
C. Michael GibsonThe PERFUSE Study Group, Cardiovascular Division, Department of Medicine, Beth Israel Deaconess Medical, Harvard Medical School, Boston, MA, USAView further author information
&
Dominick J. AngiolilloDivision of Cardiology, University of Florida College of Medicine, Jacksonville, FL, USACorrespondence[email protected]
View further author information
Pages 997-1005 | Received 13 Jul 2018, Accepted 23 Oct 2018, Published online: 03 Nov 2018

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Amit Rout, Ajaypaul Sukhi, Rahul Chaudhary, Kevin P Bliden, Udaya S Tantry & Paul A Gurbel. (2020) Investigational drugs in phase II clinical trials for acute coronary syndromes. Expert Opinion on Investigational Drugs 29:1, pages 33-47.
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Articles from other publishers (15)

Minzhi Yu, Kristen Hong Dorsey, Troy Halseth & Anna Schwendeman. (2023) Enhancement of Anti-inflammatory Effects of Synthetic High-Density Lipoproteins by Incorporation of Anionic Lipids. Molecular Pharmaceutics 20:11, pages 5454-5462.
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Luis Ortega-Paz, Salvatore Giordano, Davide Capodanno, Roxana Mehran, C. Michael Gibson & Dominick J. Angiolillo. (2023) Clinical Pharmacokinetics and Pharmacodynamics of CSL112. Clinical Pharmacokinetics 62:4, pages 541-558.
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Kui Cui, Xinlei GaoBeibei WangHao WuKulandaisamy Arulsamy, Yunzhou DongYuling XiaoXingya JiangMarina V. MalovichkoKathryn LiQianman Peng, Yao Wei Lu, Bo ZhuRongbin ZhengScott WongDouglas B. Cowan, MacRae Linton, Sanjay SrivastavaJinjun Shi, Kaifu Chen & Hong Chen. (2023) Epsin Nanotherapy Regulates Cholesterol Transport to Fortify Atheroma Regression. Circulation Research 132:1.
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Sunil A. Nankar, Priyanka S. Kawathe & Abhay H. Pande. (2022) HDL, ApoA-I and ApoE-Mimetic Peptides: Potential Broad Spectrum Agent for Clinical Use?. International Journal of Peptide Research and Therapeutics 28:2.
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Haoyu Wu, Chen Wang, Gulinigaer Tuerhongjiang, Xiangrui Qiao, Yiming Hua, Jianqing She & Zuyi Yuan. (2023) Circulating lipid and lipoprotein profiles and their correlation to cardiac function and cardiovascular outcomes in patients with acute myocardial infarction. Journal of Investigative Medicine 69:7, pages 1310-1317.
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Bo Zheng, Danielle Duffy, Pierluigi Tricoci, Helen Kastrissios, Marc Pfister, Samuel D. Wright, Andreas Gille & Michael A. Tortorici. (2020) Pharmacometric analyses to characterize the effect of CSL112 on apolipoprotein A‐I and cholesterol efflux capacity in acute myocardial infarction patients. British Journal of Clinical Pharmacology 87:6, pages 2558-2571.
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Aditya Gupta, Reena Sharma, Kaushik Kuche & Sanyog Jain. (2021) Exploring the therapeutic potential of the bioinspired reconstituted high density lipoprotein nanostructures. International Journal of Pharmaceutics 596, pages 120272.
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Natalie C. Ward & Gerald F. Watts. 2021. Therapeutic Lipidology. Therapeutic Lipidology 615 636 .
Himani Thakkar, Vinnyfred Vincent, Ambuj Roy, Sandeep Singh, Lakshmy Ramakrishnan, Mani Kalaivani & Archna Singh. (2020) HDL functions and their interaction in patients with ST elevation myocardial infarction: a case control study. Lipids in Health and Disease 19:1.
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Soumaya Ben-Aicha, Laura Casaní, Natàlia Muñoz-García, Oriol Joan-Babot, Esther Peña, Monika Aržanauskaitė, Manuel Gutierrez, Guiomar Mendieta, Teresa Padró, Lina Badimon & Gemma Vilahur. (2020) HDL (High-Density Lipoprotein) Remodeling and Magnetic Resonance Imaging–Assessed Atherosclerotic Plaque Burden. Arteriosclerosis, Thrombosis, and Vascular Biology 40:10, pages 2481-2493.
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Devinder S. Dhindsa, Pratik B. Sandesara, Michael D. Shapiro & Nathan D. Wong. (2020) The Evolving Understanding and Approach to Residual Cardiovascular Risk Management. Frontiers in Cardiovascular Medicine 7.
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Rafique Islam, Denis O. Sviridov, Steven K. Drake, Jude Tunyi, Galina Abdoulaeva, Lita A. Freeman, Richard W. Pastor & Alan T. Remaley. (2020) Incorporation of α-methylated amino acids into Apolipoprotein A-I mimetic peptides improves their helicity and cholesterol efflux potential. Biochemical and Biophysical Research Communications 526:2, pages 349-354.
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Soumaya Ben-Aicha, Lina Badimon & Gemma Vilahur. (2020) Advances in HDL: Much More than Lipid Transporters. International Journal of Molecular Sciences 21:3, pages 732.
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David Castaño, Chutima Rattanasopa, Vera F. Monteiro-Cardoso, Maria Corlianò, Yiran Liu, Shiqi Zhong, Mihaela Rusu, Elisa A. Liehn & Roshni R. Singaraja. (2020) Lipid efflux mechanisms, relation to disease and potential therapeutic aspects. Advanced Drug Delivery Reviews 159, pages 54-93.
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Johanne Silvain, Mathieu Kerneis, Maryse Guerin & Gilles Montalescot. (2019) Modulation of cholesterol efflux capacity in patients with myocardial infarction. Current Opinion in Cardiology 34:6, pages 714-720.
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