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Expert Opinion on Investigational Drugs Volume 28, 2019 - Issue 3
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Review

New drugs in early-stage clinical trials for allergic rhinitis

Enrico HefflerPersonalized Medicine, Asthma and Allergy, Humanitas Clinical and Research Center – IRCCS, Rozzano, Italy;Department of Biomedical Sciences, Humanitas University, Pieve Emanuele, ItalyView further author information
,
Luisa BrussinoDepartment of Medical Science, Allergy and Clinical Immunology, University of Torino & AO Ordine Mauriziano Umberto I, Torino, ItalyView further author information
,
Stefano Del GiaccoDepartment of Medical Sciences 'M. Aresu,' Allergy and Clinical Immunology Unit, University of Cagliari, Cagliari, ItalyView further author information
,
Giovanni PaolettiDepartment of Biomedical Sciences, Humanitas University, Pieve Emanuele, ItalyView further author information
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Paola Lucia MinciulloDepartment of Clinical and Experimental Medicine, School and Division of Allergy and Clinical Immunology, University Hospital 'G. Martino', Messina, ItalyView further author information
,
Gilda VarricchiDepartment of Translational Medical Sciences and Center for Basic and Clinical Immunology, University of Napoli Federico II, Napoli, ItalyView further author information
,
Guy ScaddingAllergy and Clinical Immunology, Division of Respiratory Science, National Heart and Lung Institute, Imperial College, Royal Brompton Hospital, London, UKView further author information
,
Luca MalvezziDepartment of Otorhinolaryngology, Humanitas Research Hospital – IRCCS, Rozzano, ItalyView further author information
,
Armando De VirgilioDepartment of Otorhinolaryngology, Humanitas Research Hospital – IRCCS, Rozzano, ItalyView further author information
,
Giuseppe SprianoDepartment of Biomedical Sciences, Humanitas University, Pieve Emanuele, Italy;Department of Otorhinolaryngology, Humanitas Research Hospital – IRCCS, Rozzano, ItalyView further author information
,
Francesca PuggioniPersonalized Medicine, Asthma and Allergy, Humanitas Clinical and Research Center – IRCCS, Rozzano, Italy;Department of Biomedical Sciences, Humanitas University, Pieve Emanuele, ItalyView further author information
,
Monica ForneroDepartment of Medical Science, Allergy and Clinical Immunology, University of Torino & AO Ordine Mauriziano Umberto I, Torino, ItalyView further author information
,
Giovanni RollaDepartment of Medical Science, Allergy and Clinical Immunology, University of Torino & AO Ordine Mauriziano Umberto I, Torino, ItalyView further author information
&
Giorgio Walter CanonicaPersonalized Medicine, Asthma and Allergy, Humanitas Clinical and Research Center – IRCCS, Rozzano, Italy;Department of Biomedical Sciences, Humanitas University, Pieve Emanuele, ItalyCorrespondence[email protected]
View further author information
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Pages 267-273 | Received 13 Dec 2018, Accepted 15 Jan 2019, Published online: 24 Jan 2019

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Amelia Licari, Riccardo Castagnoli, Maria Angela Tosca, Gianluigi Marseglia & Giorgio Ciprandi. (2019) Personalized therapies for the treatment of allergic rhinitis. Expert Review of Precision Medicine and Drug Development 4:5, pages 275-281.
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Articles from other publishers (11)

Giovanni Paoletti, Giovanni Costanzo, Lorenzo Del Moro, Federico Spataro, Palma Carlucci & Danilo Di Bona. (2023) Editorial: pharmacotherapy and evidence-based medicine section. Current Opinion in Allergy & Clinical Immunology 23:4, pages 307-308.
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Giovanni Costanzo, Giulia Anna Maria Luigia Costanzo, Lorenzo Del Moro, Emanuele Nappi, Corrado Pelaia, Francesca Puggioni, Giorgio Walter Canonica, Enrico Heffler & Giovanni Paoletti. (2023) Mast Cells in Upper and Lower Airway Diseases: Sentinels in the Front Line. International Journal of Molecular Sciences 24:11, pages 9771.
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Kamil Janeczek, Wioleta Kowalska, Michał Zarobkiewicz, Dorota Suszczyk, Marek Mikołajczyk, Ewa Markut-Miotła, Izabela Morawska-Michalska, Adrian Bakiera, Aleksandra Tomczak, Agnieszka Kaczyńska, Andrzej Emeryk, Jacek Roliński & Krystyna Piotrowska-Weryszko. (2023) Effect of immunostimulation with bacterial lysate on the clinical course of allergic rhinitis and the level of γδT, iNKT and cytotoxic T cells in children sensitized to grass pollen allergens: A randomized controlled trial. Frontiers in Immunology 14.
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Yara Zoabi, Francesca Levi-Schaffer & Ron Eliashar. (2022) Allergic Rhinitis: Pathophysiology and Treatment Focusing on Mast Cells. Biomedicines 10:10, pages 2486.
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Mastiyage R Goonathilake, Sara Waqar, Sheeba George, Wilford Jean-Baptiste, Amina Yusuf Ali, Bithaiah Inyang, Feeba Sam Koshy, Kitty George, Prakar Poudel, Roopa Chalasani & Lubna Mohammed. (2022) Can Phosphodiesterase 4 Inhibitor Therapy Be Used in Respiratory Diseases Other Than Chronic Obstructive Pulmonary Disease?. Cureus.
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Pierandrea Morandini, Maria Elena Laino, Giovanni Paoletti, Alessandro Carlucci, Tobia Tommasini, Giovanni Angelotti, Jack Pepys, Giorgio Walter Canonica, Enrico Heffler, Victor Savevski & Francesca Puggioni. (2022) Artificial intelligence processing electronic health records to identify commonalities and comorbidities cluster at Immuno Center Humanitas. Clinical and Translational Allergy 12:6.
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Bo-Jeong Pyun, Joo Young Lee, Yu Jin Kim, Kon-Young Ji, Dong Ho Jung, Ki-Sun Park, Kyuhyung Jo, Susanna Choi, Myung-A Jung, Yun Hee Kim & Taesoo Kim. (2021) Gardenia jasminoides Attenuates Allergic Rhinitis-Induced Inflammation by Inhibiting Periostin Production. Pharmaceuticals 14:10, pages 986.
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Jean Bousquet, Josep M. Anto, Claus Bachert, Ilaria Baiardini, Sinthia Bosnic-Anticevich, G. Walter Canonica, Erik Melén, Oscar Palomares, Glenis K. Scadding, Alkis Togias & Sanna Toppila-Salmi. (2020) Allergic rhinitis. Nature Reviews Disease Primers 6:1.
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Viera Janosova, Vladimir Calkovsky, Heiko Pedan, Estera Behanova, Andrej Hajtman & Andrea Calkovska. (2020) Phosphodiesterase 4 Inhibitors in Allergic Rhinitis/Rhinosinusitis. Frontiers in Pharmacology 11.
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Ricardo J. Saranz, Alejandro Lozano, Natalia A. Lozano, Graciela Alegre & Marina F. Ponzio. (2020) The Roadmap From Allergic Rhinitis to Asthma. Current Treatment Options in Allergy 7:1, pages 110-123.
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Daniel Vázquez, Cora Isabel Onetti, Claudio Alberto Parisi, Jorge César Martinez, Juan Croce, Pablo Moreno, Marcela Garcia, Juan Carlos Ivancevich & R. Maximiliano Gómez. (2020) Tratamiento de la rinitis alérgica en pediatría en Argentina. Documento de actualización. Revista Alergia México 67, pages S1-S28.
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