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Expert Opinion on Investigational Drugs Volume 28, 2019 - Issue 3
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Drug Evaluation

Early clinical trials of Toca 511 and Toca FC show a promising novel treatment for recurrent malignant glioma

Brandon D. PhilbrickDepartment of Neurosurgery, Emory University School of Medicine, Atlanta, GA, USAView further author information
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D. Cory AdamsonDepartment of Neurosurgery, Emory University School of Medicine, Atlanta, GA, USA;Neurosurgery Section, Atlanta VA Medical Center, Decatur, GA, USACorrespondence[email protected]
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Pages 207-216 | Received 29 Aug 2018, Accepted 16 Jan 2019, Published online: 07 Feb 2019

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Lidia Gatto, Enrico Franceschi, Alicia Tosoni, Vincenzo Di Nunno, Stefania Bartolini & Alba Ariela Brandes. (2023) Glioblastoma treatment slowly moves toward change: novel druggable targets and translational horizons in 2022. Expert Opinion on Drug Discovery 18:3, pages 269-286.
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Brandon Philbrick & David C. Adamson. (2019) DNX-2401: an investigational drug for the treatment of recurrent glioblastoma. Expert Opinion on Investigational Drugs 28:12, pages 1041-1049.
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Ilona Nowak, Marcel Madej, Julia Secemska, Robert Sarna & Barbara Strzalka-Mrozik. (2023) Virus-Based Biological Systems as Next-Generation Carriers for the Therapy of Central Nervous System Diseases. Pharmaceutics 15:7, pages 1931.
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Tanvir Ahmed. (2023) Oncolytic virotherapy using neural stem cells as a novel treatment option for glioblastoma multiforme. MedComm – Oncology 2:1.
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Penghao Liu, Yaning Wang, Yuekun Wang, Ziren Kong, Wanqi Chen, Jiatong Li, Wenlin Chen, Yuanren Tong, Wenbin Ma & Yu Wang. (2020) Effects of oncolytic viruses and viral vectors on immunity in glioblastoma. Gene Therapy 29:3-4, pages 115-126.
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Nasser Hashemi Goradel, Arezoo Alizadeh, Shahnaz Hosseinzadeh, Mitra Taghipour, Zeinab Ghesmati, Arash Arashkia & Babak Negahdari. (2022) Oncolytic virotherapy as promising immunotherapy against cancer: mechanisms of resistance to oncolytic viruses. Future Oncology 18:2, pages 245-259.
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G. P. Guens, V. D. Sanikovich, V. A. Mileyko & A. A. Lebedeva. (2021) Glioblastoma: a molecular genetic portrait and modern therapeutic strategies for drug treatment. Advances in Molecular Oncology 8:3, pages 60-76.
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Ani-Simona Sevastre, Alexandra Costachi, Ligia Tataranu, Corina Brandusa, Stefan Artene, Olivian Stovicek, Oana Alexandru, Suzana Danoiu, Veronica Sfredel & Anica Dricu. (2021) Glioblastoma pharmacotherapy: A multifaceted perspective of conventional and emerging treatments (Review). Experimental and Therapeutic Medicine 22:6.
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Shalini Sundramurthi Chelliah, Ervin Ashley Lourdes Paul, Muhamad Noor Alfarizal Kamarudin & Ishwar Parhar. (2021) Challenges and Perspectives of Standard Therapy and Drug Development in High-Grade Gliomas. Molecules 26:4, pages 1169.
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David Olayinka Kamson, Harmon Singh Khela & John Laterra. 2021. Glioblastoma Resistance to Chemotherapy: Molecular Mechanisms and Innovative Reversal Strategies. Glioblastoma Resistance to Chemotherapy: Molecular Mechanisms and Innovative Reversal Strategies 31 77 .
Vera Kemp, Martine L.M. Lamfers, Gabri van der Pluijm, Bernadette G. van den Hoogen & Rob C. Hoeben. (2020) Developing oncolytic viruses for clinical use: A consortium approach. Cytokine & Growth Factor Reviews 56, pages 133-140.
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P. D. Delgado-López, P. Saiz-López, R. Gargini, E. Sola-Vendrell & S. Tejada. (2020) A comprehensive overview on the molecular biology of human glioma: what the clinician needs to know. Clinical and Translational Oncology 22:11, pages 1909-1922.
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David S Kim. (2020) Cancer stem cell plasticity in glioblastoma multiforme: a perspective on future directions in oncolytic virotherapy. Future Oncology 16:28, pages 2251-2264.
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Yungang Wang, Yanxia Ding, Yijun Deng, Yu Zheng & Shengjun Wang. (2020) Role of myeloid-derived suppressor cells in the promotion and immunotherapy of colitis-associated cancer. Journal for ImmunoTherapy of Cancer 8:2, pages e000609.
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Lee, Kim, Lee, Kang, Shin, Oh, Koo, Kim, Kim, Kong, Nam & Lee. (2019) Novel Semi-Replicative Retroviral Vector Mediated Double Suicide Gene Transfer Enhances Antitumor Effects in Patient-Derived Glioblastoma Models. Cancers 11:8, pages 1090.
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