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Expert Opinion on Investigational Drugs Volume 28, 2019 - Issue 5
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Drug Evaluation

Dasatinib as an investigational drug for the treatment of Philadelphia chromosome-positive acute lymphoblastic leukemia in adults

Marte Karen BrattåsDepartment of Medicine, Haraldsplass Deaconess Hospital, Bergen, NorwayView further author information
,
Håkon ReikvamDepartment of Medicine, Haukeland University Hospital, Bergen, NorwayView further author information
,
Tor Henrik Anderson TvedtDepartment of Medicine, Haukeland University Hospital, Bergen, NorwayView further author information
&
Øystein BruserudDepartment of Medicine, Haukeland University Hospital, Bergen, Norway;Section for Hematology, Department of Clinical Science, University of Bergen, Bergen, NorwayCorrespondence[email protected]
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Pages 411-420 | Received 17 Dec 2018, Accepted 14 Mar 2019, Published online: 05 Apr 2019

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Kavita Kumari Kakarala & Kaiser Jamil. (2022) Identification of novel allosteric binding sites and multi-targeted allosteric inhibitors of receptor and non-receptor tyrosine kinases using a computational approach. Journal of Biomolecular Structure and Dynamics 40:15, pages 6889-6909.
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Laurence Booth, Andrew Poklepovic & Paul Dent. (2019) Not the comfy chair! Cancer drugs that act against multiple active sites. Expert Opinion on Therapeutic Targets 23:11, pages 893-901.
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Wenda Huang, Zhaonian Hao, Feng Mao & Dongsheng Guo. (2022) Small Molecule Inhibitors in Adult High-Grade Glioma: From the Past to the Future. Frontiers in Oncology 12.
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Håkon Reikvam, Kimberley Joanne Hatfield, Øystein Wendelbo, Roald Lindås, Philippe Lassalle & Øystein Bruserud. (2022) Endocan in Acute Leukemia: Current Knowledge and Future Perspectives. Biomolecules 12:4, pages 492.
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Maria Hernandez-Valladares, Rebecca Wangen, Elise Aasebø, Håkon Reikvam, Frode S. Berven, Frode Selheim & Øystein Bruserud. (2021) Proteomic Studies of Primary Acute Myeloid Leukemia Cells Derived from Patients Before and during Disease-Stabilizing Treatment Based on All-Trans Retinoic Acid and Valproic Acid. Cancers 13:9, pages 2143.
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Xinjie Xu, Shengkang Huang, Xinyi Xiao, Qihang Sun, Xiaoqian Liang, Sifei Chen, Zijing Zhao, Zhaochang Huo, Sanfang Tu & Yuhua Li. (2021) Challenges and Clinical Strategies of CAR T-Cell Therapy for Acute Lymphoblastic Leukemia: Overview and Developments. Frontiers in Immunology 11.
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James G. Macfarlane, David A. Dorward, Marie-Hélène Ruchaud-Sparagano, Jonathan Scott, Christopher D. Lucas, Adriano G. Rossi & A. John Simpson. (2020) Src kinase inhibition with dasatinib impairs neutrophil function and clearance of Escherichia coli infection in a murine model of acute lung injury. Journal of Inflammation 17:1.
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Chunling Zeng, Li Zhu, Xiaona Jia, Yuzhi Pang, Zhang Li, Xiaojing Lu, Feifei Xie, Lili Duan & Yuexiang Wang. (2020) Spectrum of activity of dasatinib against mutant KIT kinases associated with drug-sensitive and drug-resistant gastrointestinal stromal tumors. Gastric Cancer 23:5, pages 837-847.
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Lukasz Komorowski, Klaudyna Fidyt, Elżbieta Patkowska & Malgorzata Firczuk. (2020) Philadelphia Chromosome-Positive Leukemia in the Lymphoid Lineage—Similarities and Differences with the Myeloid Lineage and Specific Vulnerabilities. International Journal of Molecular Sciences 21:16, pages 5776.
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Abdulaziz B. Hamid & Ruben C. Petreaca. (2020) Secondary Resistant Mutations to Small Molecule Inhibitors in Cancer Cells. Cancers 12:4, pages 927.
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Adele K. Fielding. (2019) Curing Ph+ ALL: assessing the relative contributions of chemotherapy, TKIs, and allogeneic stem cell transplant. Hematology 2019:1, pages 24-29.
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