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Review

Investigational drugs currently in phase II clinical trials for actinic keratosis

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Pages 629-642 | Received 25 Feb 2019, Accepted 21 Jun 2019, Published online: 04 Jul 2019

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Virginia Garofalo, Francesco Geraci, Monia Di Prete, Caterina Lanna, Flavia Lozzi, Terenzio Cosio, Sara Lambiase, Ruslana Gaeta Shumak, Cosimo Di Raimondo, Laura Diluvio, Luca Bianchi & Elena Campione. (2022) Early clinical response to 5-fluorouracil 0.5% and salicylic acid 10% topical solution in the treatment of actinic keratoses of the head: an observational study. Journal of Dermatological Treatment 33:5, pages 2664-2669.
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Vinzent Kevin Ortner, Berit Johansen, Kim Kilov, Alejandro Castillo Mondragón, Tore Duvold, Jesper Kihl, Felicity J Ashcroft, Astrid J Feuerherm, Charlotte Pind Laugesen, Maiken Lise Marcker Espersen, Ionela Manole, Ari Pall Isberg, Anders Daniel Andersen, Elin Rakvaag, John R Zibert & Merete Haedersdal. (2022) The Copenhagen Actinic Keratosis Study (COAKS). A decentralised clinical trial to evaluate tolerability, safety and efficacy of daily field-directed topical treatment with cytosolic phospholipase A 2 inhibitor, AVX001, in participants with actinic keratosis: protocol for a randomised controlled phase I/IIa trial . BMJ Open 12:10, pages e061012.
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Jon Chim Bai‐Habelski, Annette Ko, Christoph Ortland, Marcus Stocker, Andrea Ebeling & Uwe Reinhold. (2022) 5‐ALA loaded self‐adhesive patch‐PDT is effective and safe in the treatment of actinic keratoses on hands and arms . Experimental Dermatology 31:9, pages 1385-1391.
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Bruno Casciaro, Laura Mangiardi, Floriana Cappiello, Isabella Romeo, Maria Rosa Loffredo, Antonia Iazzetti, Andrea Calcaterra, Antonella Goggiamani, Francesca Ghirga, Maria Luisa Mangoni, Bruno Botta & Deborah Quaglio. (2020) Naturally-Occurring Alkaloids of Plant Origin as Potential Antimicrobials against Antibiotic-Resistant Infections. Molecules 25:16, pages 3619.
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