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Expert Opinion on Investigational Drugs Volume 29, 2020 - Issue 7
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Review

Investigational treatments in phase I and II clinical trials: a systematic review in chronic obstructive pulmonary disease (COPD)

Luigino Calzettaa Unit of Respiratory Medicine, Department of Experimental Medicine, University of Rome “Tor Vergata”, Rome, ItalyCorrespondence[email protected]
ORCID Iconhttps://orcid.org/0000-0003-0456-069XView further author information
ORCID Icon,
Beatrice Ludovica Ritondoa Unit of Respiratory Medicine, Department of Experimental Medicine, University of Rome “Tor Vergata”, Rome, ItalyView further author information
,
Maria Gabriella Materab Unit of Pharmacology, Department of Experimental Medicine, University of Campania Luigi Vanvitelli, Naples, ItalyView further author information
,
Gabriella Pezzutoc Division of Respiratory Medicine, University Hospital “Tor Vergata”, Rome, ItalyView further author information
,
Mario Cazzolaa Unit of Respiratory Medicine, Department of Experimental Medicine, University of Rome “Tor Vergata”, Rome, ItalyORCID Iconhttps://orcid.org/0000-0003-4895-9707View further author information
ORCID Icon &
Paola Rogliania Unit of Respiratory Medicine, Department of Experimental Medicine, University of Rome “Tor Vergata”, Rome, ItalyView further author information
Pages 723-738 | Received 25 Sep 2019, Accepted 11 May 2020, Published online: 27 May 2020

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Luigino Calzetta, Elena Pistocchini, Alfredo Chetta, Paola Rogliani & Mario Cazzola. (2023) Experimental drugs in clinical trials for COPD: artificial intelligence via machine learning approach to predict the successful advance from early-stage development to approval. Expert Opinion on Investigational Drugs 32:6, pages 525-536.
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Kaixi Ding, Wei Jiang, Wenling Zhan, Chunping Xiong, Jieling Chen, Yu Wang, Huanan Jia & Ming Lei. (2023) The therapeutic potential of quercetin for cigarette smoking–induced chronic obstructive pulmonary disease: a narrative review. Therapeutic Advances in Respiratory Disease 17, pages 175346662311708.
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Nicola P. Bondonno, Benjamin H. Parmenter, Frederik Dalgaard, Kevin Murray, Daniel Bech Rasmussen, Cecilie Kyrø, Aedin Cassidy, Catherine P. Bondonno, Joshua R. Lewis, Kevin D. Croft, Gunnar Gislason, Augustin Scalbert, Anne Tjønneland, Kim Overvad, Anja Olsen & Jonathan M. Hodgson. (2022) Flavonoid intakes inversely associate with COPD in smokers. European Respiratory Journal 60:2, pages 2102604.
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Suxiang Feng, Jie Yuan, Di Zhao, Rongrong Li, Xuefang Liu, Yange Tian & Jiansheng Li. (2022) Systematic characterization of the effective constituents and molecular mechanisms of Ardisiae Japonicae Herba using UPLC-Orbitrap Fusion MS and network pharmacology. PLOS ONE 17:6, pages e0269087.
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