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Expert Opinion on Investigational Drugs Volume 29, 2020 - Issue 11
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DRUG EVALUATION

Mavacamten: a novel small molecule modulator of β-cardiac myosin for treatment of hypertrophic cardiomyopathy

Albree Tower-Radera Department of Medicine (Division of Cardiology), Massachusetts General Hospital, Harvard Medical School, Boston, MA, USAView further author information
,
Jay Ramchandb Heart and Vascular Institute, Cleveland Clinic, Cleveland, OH, USAORCID Iconhttps://orcid.org/0000-0001-8591-1986View further author information
ORCID Icon,
Steve E. Nissenb Heart and Vascular Institute, Cleveland Clinic, Cleveland, OH, USAView further author information
&
Milind Y. Desaib Heart and Vascular Institute, Cleveland Clinic, Cleveland, OH, USACorrespondence[email protected]
View further author information
Pages 1171-1178 | Received 15 Jun 2020, Accepted 05 Sep 2020, Published online: 20 Sep 2020

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Read on this site (1)

Tiffany Dong, Ben Alencherry, Susan Ospina & Milind Y Desai. (2023) Review of Mavacamten for Obstructive Hypertrophic Cardiomyopathy and Future Directions. Drug Design, Development and Therapy 17, pages 1097-1106.
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Articles from other publishers (9)

Suman Nag, Sampath K. GollapudiCarlos L. del Rio, James A. Spudich & Robert McDowell. (2023) Mavacamten, a precision medicine for hypertrophic cardiomyopathy: From a motor protein to patients. Science Advances 9:30.
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Ma’Lik Woodland & Rami A. Al-Horani. (2023) New Era: Mavacamten for Obstructive Hypertrophic Cardiomyopathy. Cardiovascular & Hematological Agents in Medicinal Chemistry 21:2, pages 78-83.
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Shuo Yuan, Dan‐Dan Shen, Rui Jia, Ju‐Shan Sun, Jian Song & Hong‐Min Liu. (2023) New drug approvals for 2022: Synthesis and clinical applications. Medicinal Research Reviews.
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Antonio da Silva Menezes Junior, Thais Aratak Marques Taia, Camila Cássia Canzi, Ana Lígia Valeriano de Oliveira, Lucas Eduardo Almeida França, Aline Lins da Silva, Matheus Araújo Borges & Guilherme Diniz Prudente. 2023. Updates on Cardiac Defibrillation, Cardioversion and AED Development [Working Title]. Updates on Cardiac Defibrillation, Cardioversion and AED Development [Working Title].
Filippos Triposkiadis, Andrew Xanthopoulos, Konstantinos Dean Boudoulas, Grigorios Giamouzis, Harisios Boudoulas & John Skoularigis. (2022) The Interventricular Septum: Structure, Function, Dysfunction, and Diseases. Journal of Clinical Medicine 11:11, pages 3227.
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Alejandro Echavarria Cross, Luis Guillermo Pájaro-Franco, Sebastián Naranjo-Restrepo & Daniela Sánchez-Présiga. (2021) Cardiomiopatía hipertrófica en fase de burnout. CES Medicina 35:3, pages 305-315.
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Erika Hutt, Steven E Nissen & Milind Y Desai. (2021) Unmet needs in the treatment of hypertrophic cardiomyopathy. Future Cardiology 17:7, pages 1261-1267.
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Milind Y. Desai, Kathy Wolski, Anjali Owens, Srihari S. Naidu, Jeffrey B. Geske, Nicholas G. Smedira, Hartzell Schaff, Kathy Lampl, Ellen McErlean, Christina Sewell, David Zhang, Jay M. Edelberg, Amy J. Sehnert & Steven E. Nissen. (2021) Study design and rationale of VALOR-HCM: evaluation of mavacamten in adults with symptomatic obstructive hypertrophic cardiomyopathy who are eligible for septal reduction therapy. American Heart Journal 239, pages 80-89.
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Mila Glavaški & Lazar Velicki. (2021) Shared Molecular Mechanisms of Hypertrophic Cardiomyopathy and Its Clinical Presentations: Automated Molecular Mechanisms Extraction Approach. Life 11:8, pages 785.
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