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Expert Opinion on Investigational Drugs Volume 29, 2020 - Issue 12
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Review

Clinical complexity of utilizing FGFR inhibitors in cancer therapeutics

Sreenivasa R. Chandanaa Phase I Program, START Midwest, Grand Rapids, MI, USA;b Department of Medical Oncology, Cancer and Hematology Centers of Western Michigan, Grand Rapids, MI, USA;c Department of Medicine, College of Human Medicine, Michigan State University, East Lansing, MI, USACorrespondence[email protected]
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,
Hani M. Babikerd Early Phase Clinical Trials Program, University of Arizona Cancer Center, Tucson, AZ, USAView further author information
&
Daruka Mahadevand Early Phase Clinical Trials Program, University of Arizona Cancer Center, Tucson, AZ, USA;e Division of Hematology-Oncology, Mays Cancer Center, University of Texas Health San Antonio, San Antonio, TX, USAView further author information
Pages 1413-1429 | Received 01 Jun 2020, Accepted 14 Oct 2020, Published online: 06 Nov 2020

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Craig W. Freyer, Mitchell E. Hughes, Alison Carulli, Adam Bagg & Elizabeth Hexner. (2023) Pemigatinib for the treatment of myeloid/lymphoid neoplasms with FGFR1 rearrangement. Expert Review of Anticancer Therapy 23:4, pages 351-359.
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Chen Hong, Jianping Wei, Tao Zhou, Xia Wang & Jing Cai. (2022) FGFR2-ERC1: A Subtype of FGFR2 Oncogenic Fusion Variant in Lung Adenocarcinoma and the Response to Anlotinib. OncoTargets and Therapy 15, pages 651-657.
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Articles from other publishers (5)

Xinyi Zheng, Hang Wang, Junyue Deng, Minghe Yao, Xiuhe Zou, Fan Zhang & Xuelei Ma. (2023) Safety and efficacy of the pan-FGFR inhibitor erdafitinib in advanced urothelial carcinoma and other solid tumors: A systematic review and meta-analysis. Frontiers in Oncology 12.
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Ahmad Najem, Laura Soumoy, Malak Sabbah, Mohammad Krayem, Ahmad Awada, Fabrice Journe & Ghanem E. Ghanem. (2022) Understanding Molecular Mechanisms of Phenotype Switching and Crosstalk with TME to Reveal New Vulnerabilities of Melanoma. Cells 11:7, pages 1157.
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Riyad N. H. Seervai, Woo Cheal Cho, Emily Y. Chu, Mario L. Marques‐Piubelli, Debora A. Ledesma, Kristen Richards, Meghan M. Heberton, Kelly C. Nelson, Priyadharsini Nagarajan, Carlos A. Torres‐Cabala, Victor G. Prieto & Jonathan L. Curry. (2021) Diverse landscape of dermatologic toxicities from small‐molecule inhibitor cancer therapy. Journal of Cutaneous Pathology 49:1, pages 61-81.
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Kai Ran, Jun Zeng, Guoquan Wan, Xiaojie He, Zhanzhan Feng, Wang Xiang, Wei Wei, Xiang Hu, Ningyu Wang, Zhihao Liu & Luoting Yu. (2021) Design, synthesis and biological evaluations of a series of Pyrido[1,2-a]pyrimidinone derivatives as novel selective FGFR inhibitors. European Journal of Medicinal Chemistry 220, pages 113499.
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Richard J. Epstein, Li Jun Tian & Yan Fei Gu. (2021) 2b or Not 2b: How Opposing FGF Receptor Splice Variants Are Blocking Progress in Precision Oncology. Journal of Oncology 2021, pages 1-16.
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