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Expert Opinion on Investigational Drugs Volume 31, 2022 - Issue 3
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Review

Investigational spleen tyrosine kinase (SYK) inhibitors for the treatment of autoimmune diseases

Su’an Tanga Clinical Research Centre, Zhujiang Hospital, Southern Medical University, Guangzhou, Guangdong, China;b Centre of Orthopedics, Zhujiang Hospital, Southern Medical University, Guangzhou, Guangdong, ChinaView further author information
,
Qinghong Yuc Department of Rheumatology and Clinical Immunology, Zhujiang Hospital, Southern Medical University, Guangzhou, Guangdong, ChinaView further author information
&
Changhai Dinga Clinical Research Centre, Zhujiang Hospital, Southern Medical University, Guangzhou, Guangdong, China;d Menzies Institute for Medical Research, University of Tasmania, Hobart, Tasmania, AustraliaCorrespondence[email protected]
ORCID Iconhttps://orcid.org/0000-0002-9479-730XView further author information
ORCID Icon
Pages 291-303 | Received 26 Aug 2021, Accepted 06 Feb 2022, Published online: 18 Feb 2022

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Nichola Cooper, Waleed Ghanima, Quentin A Hill, Phillip LR Nicolson, Vadim Markovtsov & Craig Kessler. (2023) Recent advances in understanding spleen tyrosine kinase (SYK) in human biology and disease, with a focus on fostamatinib. Platelets 34:1.
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Clayton H. Rische, Ariel H. Thames, Rebecca A. Krier-Burris, Jeremy A. O’Sullivan, Bruce S. Bochner & Evan A. Scott. (2023) Drug delivery targets and strategies to address mast cell diseases. Expert Opinion on Drug Delivery 20:2, pages 205-222.
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Articles from other publishers (8)

Tamás Németh, Lili Balogh, Eszter Káposztás, Kata P. Szilveszter & Attila Mócsai. (2023) Neutrophil-Specific Syk Expression Is Crucial for Skin Disease in Experimental Epidermolysis Bullosa Acquisita. Journal of Investigative Dermatology 143:7, pages 1147-1156.
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Maria L Lozano. (2023) Expanding therapeutic options for patients with primary immune thrombocytopenia. The Lancet Haematology.
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Chi Chiu Mok. (2023) Targeted Small Molecules for Systemic Lupus Erythematosus: Drugs in the Pipeline. Drugs 83:6, pages 479-496.
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Leo S. Bleicher, Ton van Daelen, J. Dana Honeycutt, Moises Hassan, Jayaraman Chandrasekhar, William Shirley, Vickie Tsui & Uli Schmitz. (2022) Enhanced utility of AI/ML methods during lead optimization by inclusion of 3D ligand information. Frontiers in Drug Discovery 2.
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Yanbo Hao, Xiaoqian Tang, Jing Xing, Xiuzhen Sheng, Heng Chi & Wenbin Zhan. (2022) The role of Syk phosphorylation in Fc receptor mediated mIgM+ B lymphocyte phagocytosis in flounder (Paralichthys olivaceus). Fish & Shellfish Immunology 130, pages 462-471.
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Yurika Kitamura, Kosuke Nishi, Momoko Ishida, Sogo Nishimoto & Takuya Sugahara. (2022) Anti-Allergic Effect of Aqueous Extract of Coriander (Coriandrum sativum L.) Leaf in RBL-2H3 Cells and Cedar Pollinosis Model Mice. Nutraceuticals 2:3, pages 170-180.
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Qian Liu, Lijuan Hua, Chen Bao, Luxia Kong, Jiannan Hu, Chao Liu, Ziling Li, Shuyun Xu & Xiansheng Liu. (2022) Inhibition of Spleen Tyrosine Kinase Restores Glucocorticoid Sensitivity to Improve Steroid-Resistant Asthma. Frontiers in Pharmacology 13.
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Yan Tan, Meiling Zhang, Xiaoshan Chen & Yongyue Deng. (2022) Identifying a Three-Gene Signature and Associated Drugs for Hepatitis B Virus-Related Hepatocellular Carcinoma Using Comprehensive Bioinformatics Analysis. The Tohoku Journal of Experimental Medicine 258:2, pages 149-157.
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