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Biomarkers Volume 13, 2008 - Issue 1
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Research Article

Mouse arylamine N-acetyltransferase 2 (Nat2) expression during embryogenesis: a potential marker for the developing neuroendocrine system

Larissa Wakefield Department of Pharmacology, University of Oxford, Mansfield Road, Oxford, UK
,
Valerie Cornish Department of Pharmacology, University of Oxford, Mansfield Road, Oxford, UK
,
Hilary Long Department of Pharmacology, University of Oxford, Mansfield Road, Oxford, UK
,
Akane Kawamura Department of Pharmacology, University of Oxford, Mansfield Road, Oxford, UK
,
Xiaoyan Zhang Department of Pharmacology and Toxicology and James Graham Brown Center, University of Louisville School of Medecine, KentuckyUSA
,
David W. Hein Department of Pharmacology and Toxicology and James Graham Brown Center, University of Louisville School of Medecine, KentuckyUSA
&
Edith Sim Department of Pharmacology, University of Oxford, Mansfield Road, Oxford, UKCorrespondence[email protected]
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Pages 106-118 | Received 29 May 2007, Published online: 08 Oct 2008

Citations (17)

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Read on this site (2)

Malika Khelil, Bahia Djerdjouri & Bouchentouf Tayebi. (2010) N-acetyltransferase 2 (Nat2) polymorphism in the sand rat Psammomys obesus. Toxicology Mechanisms and Methods 20:8, pages 440-444.
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Edith Sim, Kylie Walters & Sotiria Boukouvala. (2008) Arylamine N-acetyltransferases: From Structure to Function. Drug Metabolism Reviews 40:3, pages 479-510.
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Articles from other publishers (15)

N. Laurieri, E. Polycarpou & E. Sim. 2018. Comprehensive Toxicology. Comprehensive Toxicology 429 467 .
Marcus W. Stepp, Galina Mamaliga, Mark A. Doll, J. Christopher States & David W. Hein. (2015) Folate-dependent hydrolysis of acetyl-coenzyme A by recombinant human and rodent arylamine N-acetyltransferases. Biochemistry and Biophysics Reports 3, pages 45-50.
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E Sim, A Abuhammad & A Ryan. (2014) Arylamine N‐acetyltransferases: from drug metabolism and pharmacogenetics to drug discovery. British Journal of Pharmacology 171:11, pages 2705-2725.
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James E. Egleton, Cyrille C. Thinnes, Peter T. Seden, Nicola Laurieri, Siu Po Lee, Kate S. Hadavizadeh, Angelina R. Measures, Alan M. Jones, Sam Thompson, Amy Varney, Graham M. Wynne, Ali Ryan, Edith Sim & Angela J. Russell. (2014) Structure–activity relationships and colorimetric properties of specific probes for the putative cancer biomarker human arylamine N-acetyltransferase 1. Bioorganic & Medicinal Chemistry 22:11, pages 3030-3054.
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Theodora Tsirka, Sotiria Boukouvala, Bogos Agianian & Giannoulis Fakis. (2014) Polymorphism p.Val231Ile alters substrate selectivity of drug-metabolizing arylamine N-acetyltransferase 2 (NAT2) isoenzyme of rhesus macaque and human. Gene 536:1, pages 65-73.
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Edith Sim, Giannoulis Fakis, Nicola Laurieri & Sotiria Boukouvala. 2012. Current Concepts in Drug Metabolism and Toxicology. Current Concepts in Drug Metabolism and Toxicology 169 205 .
Muriel J. Harris & Diana M. Juriloff. (2010) An update to the list of mouse mutants with neural tube closure defects and advances toward a complete genetic perspective of neural tube closure. Birth Defects Research Part A: Clinical and Molecular Teratology 88:8, pages 653-669.
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Larissa Wakefield, Sotiria Boukouvala & Edith Sim. (2010) Characterisation of CpG methylation in the upstream control region of mouse Nat2: Evidence for a gene–environment interaction in a polymorphic gene implicated in folate metabolism. Gene 452:1, pages 16-21.
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E. Sim, E. Fullam & L. Wakefield. 2010. Comprehensive Toxicology. Comprehensive Toxicology 385 412 .
Angela J. Russell, Isaac M. Westwood, Matthew H.J. Crawford, James Robinson, Akane Kawamura, Christina Redfield, Nicola Laurieri, Edward D. Lowe, Stephen G. Davies & Edith Sim. (2009) Selective small molecule inhibitors of the potential breast cancer marker, human arylamine N-acetyltransferase 1, and its murine homologue, mouse arylamine N-acetyltransferase 2. Bioorganic & Medicinal Chemistry 17:2, pages 905-918.
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David W. Hein, Jean Bendaly, Jason R. Neale & Mark A. Doll. (2008) Systemic Functional Expression of N -Acetyltransferase Polymorphism in the F344 Nat2 Congenic Rat . Drug Metabolism and Disposition 36:12, pages 2452-2459.
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Edith Sim, Nathan Lack, Chan-Ju Wang, Hilary Long, Isaac Westwood, Elizabeth Fullam & Akane Kawamura. (2008) Arylamine N-acetyltransferases: Structural and functional implications of polymorphisms. Toxicology 254:3, pages 170-183.
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Lesley A Stanley & Edith Sim. (2008) Update on the pharmacogenetics of NATs: structural considerations. Pharmacogenomics 9:11, pages 1673-1693.
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Sotiria BoukouvalaIsaac M Westwood, Neville J Butcher & Giannoulis Fakis. (2008) Current trends in N -acetyltransferase research arising from the 2007 International NAT Workshop . Pharmacogenomics 9:6, pages 765-771.
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Akane Kawamura, Isaac Westwood, Larissa Wakefield, Hilary Long, Naixia Zhang, Kylie Walters, Christina Redfield & Edith Sim. (2008) Mouse N-acetyltransferase type 2, the homologue of human N-acetyltransferase type 1. Biochemical Pharmacology 75:7, pages 1550-1560.
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