Advanced search
Publication Cover
Biomarkers Volume 13, 2008 - Issue 6
Submit an article Journal homepage
176
Views
19
CrossRef citations to date
0
Altmetric
Research Article

Cyclin B1 is an efficacy-predicting biomarker for Chk1 inhibitors

Zhan Xiao Cancer Research, Abbott Laboratories, 100 Abbott Park Rd.Abbott Park, IL, 60064-6101, USA,
,
John Xue Cancer Research, Abbott Laboratories, 100 Abbott Park Rd.Abbott Park, IL, 60064-6101, USA,
,
Wen-Zhen Gu Cancer Research, Abbott Laboratories, 100 Abbott Park Rd.Abbott Park, IL, 60064-6101, USA,
,
Mai Bui Cancer Research, Abbott Laboratories, 100 Abbott Park Rd.Abbott Park, IL, 60064-6101, USA,
,
Gaoquan Li Cancer Research, Abbott Laboratories, 100 Abbott Park Rd.Abbott Park, IL, 60064-6101, USA,
,
Zhi-Fu Tao Cancer Research, Abbott Laboratories, 100 Abbott Park Rd.Abbott Park, IL, 60064-6101, USA,
,
Nan-Horng Lin Cancer Research, Abbott Laboratories, 100 Abbott Park Rd.Abbott Park, IL, 60064-6101, USA,
,
Thomas J. Sowin Cancer Research, Abbott Laboratories, 100 Abbott Park Rd.Abbott Park, IL, 60064-6101, USA,
&
Haiying Zhang Cancer Research, Abbott Laboratories, 100 Abbott Park Rd.Abbott Park, IL, 60064-6101, USA, Correspondence[email protected]
 show all
Pages 579-596 | Received 21 Aug 2007, Accepted 17 Mar 2008, Published online: 07 Nov 2008

Citations (19)

Keep up to date with the latest research on this topic with citation updates for this article.

Subscribe to citation updates

Read on this site (4)

Xinyi Lei, Jing Jing, Miao Zhang, Bingsheng Guan, Zhiyong Dong & Cunchuan Wang. (2021) Bioinformatic Identification of Hub Genes and Analysis of Prognostic Values in Colorectal Cancer. Nutrition and Cancer 73:11-12, pages 2568-2578.
Read now
Inger Brandsma, Emmy D.G. Fleuren, Chris T. Williamson & Christopher J. Lord. (2017) Directing the use of DDR kinase inhibitors in cancer treatment. Expert Opinion on Investigational Drugs 26:12, pages 1341-1355.
Read now
Yifeng Fang, Hong Yu, Xiao Liang, Junfen Xu & Xiujun Cai. (2014) Chk1-induced CCNB1 overexpression promotes cell proliferation and tumor growth in human colorectal cancer. Cancer Biology & Therapy 15:9, pages 1268-1279.
Read now
Christopher J Del Nagro, Jonathan Choi, Yang Xiao, Linda Rangell, Sankar Mohan, Ajay Pandita, Jiping Zha, Peter K. Jackson & Thomas O'Brien. (2014) Chk1 inhibition in p53-deficient cell lines drives rapid chromosome fragmentation followed by caspase-independent cell death. Cell Cycle 13:2, pages 303-314.
Read now

Articles from other publishers (15)

Bingchen Pan, Bowen Zheng, Chengzhong Xing & Jingwei Liu. (2022) Non-Canonical Programmed Cell Death in Colon Cancer. Cancers 14:14, pages 3309.
Crossref
Abhilasha Sharma, Deep Yadav, Priyashi Rao, Sonam Sinha, Dweipayan Goswami, Rakesh M. Rawal & Neeta Shrivastava. (2022) Identification of potential therapeutic targets associated with diagnosis and prognosis of colorectal cancer patients based on integrated bioinformatics analysis. Computers in Biology and Medicine 146, pages 105688.
Crossref
Mohammad Mirza-Aghazadeh-Attari, Saber Ghazizadeh Darband, Mojtaba Kaviani, Ainaz Mihanfar, Javad Aghazadeh Attari, Bahman Yousefi & Maryam Majidinia. (2018) DNA damage response and repair in colorectal cancer: Defects, regulation and therapeutic implications. DNA Repair 69, pages 34-52.
Crossref
Doaa Hussein Zineldeen, Noha Mohamed Shafik & Sheng Fan Li. (2017) Alternative Chk1-independent S/M checkpoint in somatic cells that prevents premature mitotic entry. Medical Oncology 34:4.
Crossref
Zheng Wang, Song-Tao Lai, Ning-Yi Ma, Yun Deng, Yong Liu, Dong-Ping Wei, Jian-Dong Zhao & Guo-Liang Jiang. (2015) Radiosensitization of metformin in pancreatic cancer cells via abrogating the G2 checkpoint and inhibiting DNA damage repair. Cancer Letters 369:1, pages 192-201.
Crossref
Rebecca Rawlinson & Andrew J Massey. (2014) γH2AX and Chk1 phosphorylation as predictive pharmacodynamic biomarkers of Chk1 inhibitor-chemotherapy combination treatments. BMC Cancer 14:1.
Crossref
Barbora Orlikova, Mario Dicato & Marc Diederich. (2013) 1,000 Ways to die: natural compounds modulate non-canonical cell death pathways in cancer cells. Phytochemistry Reviews 13:1, pages 277-293.
Crossref
Renu Wadhwa, Rumani Singh, Zeenia Kaul & Sunil C. Kaul. 2013. New Advances on Disease Biomarkers and Molecular Targets in Biomedicine. New Advances on Disease Biomarkers and Molecular Targets in Biomedicine 137 157 .
Amy D Guertin, Melissa M Martin, Brian Roberts, Melissa Hurd, Xianlu Qu, Nathan R Miselis, Yaping Liu, Jing Li, Igor Feldman, Yair Benita, Andrew Bloecher, Carlo Toniatti & Stuart D Shumway. (2012) Unique functions of CHK1 and WEE1 underlie synergistic anti-tumor activity upon pharmacologic inhibition. Cancer Cell International 12:1.
Crossref
LiFeng Ning, HuiPing Wang, Dan San & JianLi Sang. (2011) C-terminal domain of Chk1 regulates its subcellular location and kinase activity for DNA repair. Chinese Science Bulletin 56:30.
Crossref
C T Cheung, R Singh, A R Yoon, M K Hasan, T Yaguchi, S C Kaul, C O Yun & R Wadhwa. (2010) Molecular characterization of apoptosis induced by CARF silencing in human cancer cells. Cell Death & Differentiation 18:4, pages 589-601.
Crossref
Michael I. Walton, Paul D. Eve, Angela Hayes, Melanie Valenti, Alexis De Haven Brandon, Gary Box, Kathy J. Boxall, G. Wynne Aherne, Suzanne A. Eccles, Florence I. Raynaud, David H. Williams, John C. Reader, Ian Collins & Michelle D. Garrett. (2010) The Preclinical Pharmacology and Therapeutic Activity of the Novel CHK1 Inhibitor SAR-020106. Molecular Cancer Therapeutics 9:1, pages 89-100.
Crossref
XiaoFang Li, Tarsha Ward, XueBiao Yao & JiaRui Wu. (2009) Chk1 prevents abnormal mitosis of S-phase HeLa cells containing DNA damage. Chinese Science Bulletin 54:22, pages 4205-4213.
Crossref
Thomas P. Matthews, Suki KlairSamantha Burns, Kathy Boxall, Michael CherryMartin FisherIsaac M. Westwood, Michael I. Walton, Tatiana McHardy, Kwai-Ming J. Cheung, Rob Van Montfort, David WilliamsG. Wynne Aherne, Michelle D. Garrett, John ReaderIan Collins. (2009) Identification of Inhibitors of Checkpoint Kinase 1 through Template Screening. Journal of Medicinal Chemistry 52:15, pages 4810-4819.
Crossref
Silvia Lapenna & Antonio Giordano. (2009) Cell cycle kinases as therapeutic targets for cancer. Nature Reviews Drug Discovery 8:7, pages 547-566.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.