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Biomarkers Volume 3, 1998 - Issue 1
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Research Article

Haemoglobin adducts from aromatic amines and tobacco specific nitrosamines in pregnant smoking and non smoking women

BIRGIT BRANNER Walther-Straub-Institut fur Pharmakologie und Toxikologie, Nussbaumstr. 26, D-80336 Munchen, Germany
,
CORNELIA KUTZER Walther-Straub-Institut fur Pharmakologie und Toxikologie, Nussbaumstr. 26, D-80336 Munchen, Germany
,
WOLFGANG WICKENPFLUG Walther-Straub-Institut fur Pharmakologie und Toxikologie, Nussbaumstr. 26, D-80336 Munchen, Germany
,
GERHARD SCHERER Analytisch-Biologisches Forschungslabor, Goethestr. 20, D-80336 Munchen, Germany
,
WOLF-DIETER HELLER Analytisch-Biologisches Forschungslabor, Goethestr. 20, D-80336 Munchen, Germany
&
ELMAR RICHTER Walther-Straub-Institut fur Pharmakologie und Toxikologie, Nussbaumstr. 26, D-80336 Munchen, Germany
Pages 35-47 | Published online: 29 Sep 2008

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Matthias K. Schorp & Donald E. Leyden. (2010) Biomonitoring of smoke constituents: exposure to 4-aminobiphenyl and 4-aminobiphenyl hemoglobin adduct levels in nonsmokers and smokers. Inhalation Toxicology 22:9, pages 725-737.
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Katharina Schütte-Borkovec, Christopher W. Heppel, Anne-Kathrin Heling & Elmar Richter. (2009) Analysis of myosmine, cotinine and nicotine in human toenail, plasma and saliva. Biomarkers 14:5, pages 278-284.
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Michael Meger, Irmtrud Meger-Kossien, Kirsten Riedel, Gerhard Scherer. (2000) Biomonitoring of environmental tobacco smoke (ETS)-related exposure to 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK). Biomarkers 5:1, pages 33-45.
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Articles from other publishers (31)

Igor Linhart, Iveta Hanzlíková, Jaroslav Mráz & Šárka Dušková. (2023) New Aminobiphenylcysteine Derivatives in Globin and Urine of Rats Dosed with 4-Aminobiphenyl, a Tobacco Smoke Carcinogen. Chemical Research in Toxicology 36:3, pages 430-437.
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M. Nasterlack. 2002. The MAK‐Collection for Occupational Health and Safety. The MAK‐Collection for Occupational Health and Safety 1 15 .
Robert Nilsson. (2017) Use of rodent data for cancer risk assessment of smokeless tobacco in the regulatory context. Regulatory Toxicology and Pharmacology 88, pages 338-348.
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Franziska Wewering, Florent Jouy, Sükran Caliskan, Stefan Kalkhof, Martin von Bergen, Andreas Luch & Sebastian Zellmer. (2017) Hepatic co-cultures in vitro reveal suitable to detect Nrf2-mediated oxidative stress responses on the bladder carcinogen o -anisidine. Toxicology in Vitro 40, pages 153-160.
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Gabriella M Johansson, Bo A G Jönsson, Anna Axmon, Christian H Lindh, Marie-Louise Lind, Mats Gustavsson, Karin Broberg, Anders Boman, Birgitta Meding, Carola Lidén & Maria Albin. (2015) Exposure of hairdressers to ortho- and meta-toluidine in hair dyes. Occupational and Environmental Medicine 72:1, pages 57-63.
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M. Nasterlack. 2002. The MAK‐Collection for Occupational Health and Safety. The MAK‐Collection for Occupational Health and Safety 1 17 .
Yin-Tak Woo & David Y. Lai. 2001. Patty's Toxicology. Patty's Toxicology 1 96 .
Karel Naiman, Martin Dračínský, Petr Hodek, Markéta Martínková, Heinz H. Schmeiser, Eva Frei & Marie Stiborová. (2012) Formation, Persistence, and Identification of DNA Adducts Formed by the Carcinogenic Environmental Pollutant o-Anisidine in Rats. Toxicological Sciences 127:2, pages 348-359.
Crossref
E. Ochsmann. 2002. The MAK‐Collection for Occupational Health and Safety. The MAK‐Collection for Occupational Health and Safety 1 18 .
Karel Naiman, Markéta Martínková, Heinz H. Schmeiser, Eva Frei & Marie Stiborová. (2011) Human cytochrome-P450 enzymes metabolize N-(2-methoxyphenyl)hydroxylamine, a metabolite of the carcinogens o-anisidine and o-nitroanisole, thereby dictating its genotoxicity. Mutation Research/Genetic Toxicology and Environmental Mutagenesis 726:2, pages 160-168.
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Marie Stiborová, Karel Naiman, Markéta Martínková, Václav Martínek, Martina Svobodová, Heinz Schmeiser & Eva Frei. (2009) Genotoxic mechanisms for the carcinogenicity of the environmental pollutants and carcinogens o-anisidine and 2-nitroanisole follow from adducts generated by their metabolite N-(2-methoxyphenyl)hydroxylamine with deoxyguanosine in DNA. Interdisciplinary Toxicology 2:1, pages 24-27.
Crossref
Christopher W. Heppel, Anne-Kathrin Heling & Elmar Richter. (2008) Ultrasensitive method for the determination of 4-hydroxy-1-(3-pyridyl)-1-butanone-releasing DNA adducts by gas chromatography–high resolution mass spectrometry in mucosal biopsies of the lower esophagus. Analytical and Bioanalytical Chemistry 393:5, pages 1525-1530.
Crossref
J.B. Havla, C.E. Hill, S.Z. Abdel-Rahman & E. Richter. (2009) Evaluation of the mutagenic effects of myosmine in human lymphocytes using the HPRT gene mutation assay. Food and Chemical Toxicology 47:1, pages 237-241.
Crossref
Karel Naiman, Helena Dračínská, Martin Dračínský, Markéta Martínková, Václav Martínek, Petr Hodek, Martin Štícha, Eva Frei & Marie Stiborová. (2008) Cytochrome P450-mediated metabolism of N-(2-methoxyphenyl)-hydroxylamine, a human metabolite of the environmental pollutants and carcinogens o-anisidine and o-nitroanisole. Interdisciplinary Toxicology 1:3-4, pages 218-224.
Crossref
Karel Naiman, Helena Dračínská, Markéta Martínková, Miroslav Šulc, Martin Dračínský, Lucie Kejíková, Petr Hodek, Jirí Hudeček, Jirí Liberda, Heinz H. Schmeiser, Eva Frei & Marie Stiborová. (2008) Redox Cycling in the Metabolism of the Environmental Pollutant and Suspected Human Carcinogen o -Anisidine by Rat and Rabbit Hepatic Microsomes . Chemical Research in Toxicology 21:8, pages 1610-1621.
Crossref
Daniela Schlöbe, Daniel Hölzle, Dorothea Hatz, Ludwig von Meyer, Anthony R. Tricker & Elmar Richter. (2008) 4-Hydroxy-1-(3-pyridyl)-1-butanone-releasing DNA adducts in lung, lower esophagus and cardia of sudden death victims. Toxicology 245:1-2, pages 154-161.
Crossref
. 2008. Tabakabhängigkeit. Tabakabhängigkeit 113 166 .
Daniel Hölzle, Daniela Schlöbe, Anthony R. Tricker & Elmar Richter. (2007) Mass spectrometric analysis of 4-hydroxy-1-(3-pyridyl)-1-butanone-releasing DNA adducts in human lung. Toxicology 232:3, pages 277-285.
Crossref
Stephen S. Hecht, Shaomei Han, Patrick M. J. Kenney, Mingyao Wang, Bruce Lindgren, Yong Wang, Yanbin Lao, J. Bradley Hochalter & Pramod Upadhyaya. (2007) Investigation of the Reaction of Myosmine with Sodium Nitrite in Vitro and in Rats. Chemical Research in Toxicology 20:3, pages 543-549.
Crossref
Mohamadi Sarkar, Regina Stabbert, Robin D. Kinser, Jan Oey, Klaus Rustemeier, Klaus von Holt, Georg Schepers, Roger A. Walk & Hans J. Roethig. (2006) CYP1A2 and NAT2 phenotyping and 3-aminobiphenyl and 4-aminobiphenyl hemoglobin adduct levels in smokers and non-smokers. Toxicology and Applied Pharmacology 213:3, pages 198-206.
Crossref
Marie Stiborová, Markéta Mikšanová, Miroslav Šulc, Helena Rýdlová, Heinz H. Schmeiser & Eva Frei. (2005) Identification of a genotoxic mechanism for the carcinogenicity of the environmental pollutant and suspected human carcinogeno-anisidine. International Journal of Cancer 116:5, pages 667-678.
Crossref
Gerhard Scherer. (2005) Biomonitoring of inhaled complex mixtures – Ambient air, diesel exhaust and cigarette smoke. Experimental and Toxicologic Pathology 57, pages 75-110.
Crossref
Yin-Tak Woo & David Y. Lai. 2001. Patty's Toxicology. Patty's Toxicology.
M. Törnqvist, C. Fred, J. Haglund, H. Helleberg, B. Paulsson & P. Rydberg. (2002) Protein adducts: quantitative and qualitative aspects of their formation, analysis and applications. Journal of Chromatography B 778:1-2, pages 279-308.
Crossref
Elmar Richter & Birgit Branner. (2002) Biomonitoring of exposure to aromatic amines: haemoglobin adducts in humans. Journal of Chromatography B 778:1-2, pages 49-62.
Crossref
Paul L. Skipper. (2002) Precision and sensitivity of aminobiphenyl hemoglobin adduct assays in a long-term population study. Journal of Chromatography B 778:1-2, pages 375-381.
Crossref
Stefan Tyroller, Wolfgang Zwickenpflug & Elmar Richter. (2002) New Sources of Dietary Myosmine Uptake from Cereals, Fruits, Vegetables, and Milk. Journal of Agricultural and Food Chemistry 50:17, pages 4909-4915.
Crossref
J. Wilp, W. Zwickenpflug & E. Richter. (2002) Nitrosation of dietary myosmine as risk factor of human cancer. Food and Chemical Toxicology 40:8, pages 1223-1228.
Crossref
Wolfgang Zwickenpflug. (2000) N -Nitrosation of Myosmine Yields HPB (4-Hydroxy-1-(3-pyridyl)-1-butanone) and NNN ( N -Nitrosonornicotine) . Journal of Agricultural and Food Chemistry 48:2, pages 392-394.
Crossref
Annie J Sasco & Harri Vainio. (2016) From in utero and childhood exposure to parental smoking to childhood cancer: a possible link and the need for action. Human & Experimental Toxicology 18:4, pages 192-201.
Crossref
Stephen S. Hecht & Anthony R. Tricker. 1999. Analytical Determination of Nicotine and Related Compounds and their Metabolites. Analytical Determination of Nicotine and Related Compounds and their Metabolites 421 488 .

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