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Research Article

Altered expression of the xenobiotic transporter P-glycoprotein in liver and liver tumours of mummichog Fundulus heteroclitus from a creosote-contaminated environment

Pages 48-58 | Published online: 29 Sep 2008

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Richard T. Di Giulio & Bryan W. Clark. (2015) The Elizabeth River Story: A Case Study in Evolutionary Toxicology. Journal of Toxicology and Environmental Health, Part B 18:6, pages 259-298.
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LeeA. Frederick, PeterA. Van Veld & CharlesD. Rice. (2007) Bioindicators of Immune Function in Creosote-adapted Estuarine Killifish, Fundulus heteroclitus . Journal of Toxicology and Environmental Health, Part A 70:17, pages 1433-1442.
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JudithS. Weis. (2002) Tolerance to Environmental Contaminants in the Mummichog, Fundulus heteroclitus . Human and Ecological Risk Assessment: An International Journal 8:5, pages 933-953.
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Yanina A. Assef, Cecilia Y. Di Prinzio & Cristina N. Horak. (2019) Differential activities of the multixenobiotic resistance mechanism in freshwater fishes inhabiting environments of Patagonia Argentina. Comparative Biochemistry and Physiology Part C: Toxicology & Pharmacology 217, pages 32-40.
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Alyssa L. Margiotta, Lisa J. Bain & Charles D. Rice. (2017) Expression of the Major Vault Protein (MVP) and Cellular Vault Particles in Fish. The Anatomical Record 300:11, pages 1981-1992.
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Patrick B. Hamilton, Gregor Rolshausen, Tamsyn M. Uren Webster & Charles R. Tyler. (2017) Adaptive capabilities and fitness consequences associated with pollution exposure in fish. Philosophical Transactions of the Royal Society B: Biological Sciences 372:1712, pages 20160042.
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Ruiming Guo, Luqing Pan, Pengfei Lin & Lei Zheng. (2017) The detoxification responses, damage effects and bioaccumulation in the scallop Chlamys farreri exposed to single and mixtures of benzo[a]pyrene and chrysene. Comparative Biochemistry and Physiology Part C: Toxicology & Pharmacology 191, pages 36-51.
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Amanda K. Riley, Melissa Chernick, Daniel R. Brown, David E. Hinton & Richard T. Di Giulio. (2016) Hepatic Responses of Juvenile Fundulus heteroclitus from Pollution-adapted and Nonadapted Populations Exposed to Elizabeth River Sediment Extract . Toxicologic Pathology 44:5, pages 738-748.
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Qiqing Chen, Xialin Hu, Rui Wang, Jin Yuan & Daqiang Yin. (2016) Fullerene inhibits benzo(a)pyrene Efflux from Cyprinus carpio hepatocytes by affecting cell membrane fluidity and P-glycoprotein expression. Aquatic Toxicology 174, pages 36-45.
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Bryan W. Clark, A. J. Bone & R. T. Di Giulio. (2013) Resistance to teratogenesis by F1 and F2 embryos of PAH-adapted Fundulus heteroclitus is strongly inherited despite reduced recalcitrance of the AHR pathway. Environmental Science and Pollution Research 21:24, pages 13898-13908.
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Sandrine P. Machado, Virgínia Cunha, Maria Armanda Reis-Henriques & Marta Ferreira. (2014) Histopathological lesions, P-glycoprotein and PCNA expression in zebrafish (Danio rerio) liver after a single exposure to diethylnitrosamine. Environmental Toxicology and Pharmacology 38:3, pages 720-732.
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Till Luckenbach, Stephan Fischer & Armin Sturm. (2014) Current advances on ABC drug transporters in fish. Comparative Biochemistry and Physiology Part C: Toxicology & Pharmacology 165, pages 28-52.
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Marta Ferreira, Joana Costa & Maria A. Reis-Henriques. (2014) ABC transporters in fish species: a review. Frontiers in Physiology 5.
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Bryan W. Clark, Ellen M. Cooper, Heather M. Stapleton & Richard T. Di Giulio. (2013) Compound- and Mixture-Specific Differences in Resistance to Polycyclic Aromatic Hydrocarbons and PCB-126 among Fundulus heteroclitus Subpopulations throughout the Elizabeth River Estuary (Virginia, USA) . Environmental Science & Technology, pages 130905080759003.
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Joana Costa, Maria Armanda Reis-Henriques, Jonathan M. Wilson & Marta Ferreira. (2013) P-glycoprotein and CYP1A protein expression patterns in Nile tilapia (Oreochromis niloticus) tissues after waterborne exposure to benzo(a)pyrene (BaP). Environmental Toxicology and Pharmacology 36:2, pages 611-625.
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Claude Amiard-Triquet, Jean-Claude Amiard & Philip RainbowClaude Amiard-Triquet, Carole Cossu-Leguille & Catherine Mouneyrac. 2012. Ecological Biomarkers. Ecological Biomarkers 45 74 .
Bryan W. Clark & Richard T. Di Giulio. (2011) Fundulus heteroclitus adapted to PAHs are cross-resistant to multiple insecticides. Ecotoxicology 21:2, pages 465-474.
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A.A. Keller & H.M. Coleman. 2011. Treatise on Estuarine and Coastal Science. Treatise on Estuarine and Coastal Science 43 70 .
Lauren P. Wills, Cole W. Matson, Chelsea D. Landon & Richard T. Di Giulio. (2010) Characterization of the recalcitrant CYP1 phenotype found in Atlantic killifish (Fundulus heteroclitus) inhabiting a Superfund site on the Elizabeth River, VA. Aquatic Toxicology 99:1, pages 33-41.
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S. Christine Paetzold, Neil W. Ross, Robert C. Richards, Martha Jones, Jocelyne Hellou & Shannon M. Bard. (2009) Up-regulation of hepatic ABCC2, ABCG2, CYP1A1 and GST in multixenobiotic-resistant killifish (Fundulus heteroclitus) from the Sydney Tar Ponds, Nova Scotia, Canada. Marine Environmental Research 68:1, pages 37-47.
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María Valeria Amé, María Verónica Baroni, Lucas Nicolás Galanti, José Luis Bocco & Daniel Alberto Wunderlin. (2009) Effects of microcystin–LR on the expression of P-glycoprotein in Jenynsia multidentata. Chemosphere 74:9, pages 1179-1186.
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