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Articles

Assessment of titanium dioxide nanoparticles toxicity via oral exposure in mice: effect of dose and particle size

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Pages 492-498 | Received 12 Dec 2018, Accepted 02 May 2019, Published online: 28 May 2019

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Nana Sun, Xiaopeng Zhang, Chunlai Liang, Haibo Liu, Yuan Zhi, Jin Fang, Huiling Wang, Zhou Yu & Xudong Jia. (2023) Genotoxicity assessment of titanium dioxide nanoparticles using a standard battery of in vivo assays. Nanotoxicology 17:6-7, pages 497-510.
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Rihane Naima, Mrad Imen, Jeljeli Mustapha, Abdelmalek Hafedh, Kacem Kamel, Sakly Mohsen & Amara Salem. (2021) Acute titanium dioxide nanoparticles exposure impaired spatial cognitive performance through neurotoxic and oxidative mechanisms in Wistar rats. Biomarkers 26:8, pages 760-769.
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Qumber Abbas, Balal Yousaf, Habib Ullah, Muhammad Ubaid Ali, Yong Sik Ok & Jörg Rinklebe. (2020) Environmental transformation and nano-toxicity of engineered nano-particles (ENPs) in aquatic and terrestrial organisms. Critical Reviews in Environmental Science and Technology 50:23, pages 2523-2581.
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Xing Zhang, Yuanyuan Song, Hongyang Gong, Chunyan Wu, Binquan Wang, Wenxuan Chen, Jiawei Hu, Hanhui Xiang, Ke Zhang & Mingkuan Sun. (2023) Neurotoxicity of Titanium Dioxide Nanoparticles: A Comprehensive Review. International Journal of Nanomedicine Volume 18, pages 7183-7204.
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Yue Cao, Jinyao Chen, Qian Bian, Junyu Ning, Ling Yong, Tong Ou, Yan Song & Sheng Wei. (2023) Genotoxicity Evaluation of Titanium Dioxide Nanoparticles In Vivo and In Vitro: A Meta-Analysis. Toxics 11:11, pages 882.
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Nandini Nalika, Mohammad Waseem, Pooja Kaushik, Mohd Salman, Syed Suhail Andrabi, Azfar Jamal & Suhel Parvez. (2023) Role of melatonin and quercetin as countermeasures to the mitochondrial dysfunction induced by titanium dioxide nanoparticles. Life Sciences 328, pages 121403.
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Fatima A Jaber. (2023) Quercetin Mitigates Oxidative Stress, Inflammation, Apoptosis, and Histopathological Alterations Induced by Chronic Titanium Dioxide Nanoparticle Exposure in the Rat Spleen. Microscopy and Microanalysis.
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Hongmei Chang, Li Li, Yaxin Deng, Guanling Song & Yan Wang. (2023) Protective effects of lycopene on TiO 2 nanoparticle‐induced damage in the liver of mice . Journal of Applied Toxicology 43:6, pages 913-928.
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M. M. Thwala, A. Afantitis, A. G. Papadiamantis, A. Tsoumanis, G. Melagraki, L. N. Dlamini, C. N. M. Ouma, P. Ramasami, R. Harris, T. Puzyn, N. Sanabria, I. Lynch & M. Gulumian. (2021) Using the Isalos platform to develop a (Q)SAR model that predicts metal oxide toxicity utilizing facet-based electronic, image analysis-based, and periodic table derived properties as descriptors. Structural Chemistry 33:2, pages 527-538.
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Jefferson de Oliveira Mallia, Russell Galea, Rajat Nag, Enda Cummins, Ruben Gatt & Vasilis Valdramidis. (2022) Nanoparticle Food Applications and Their Toxicity: Current Trends and Needs in Risk Assessment Strategies. Journal of Food Protection 85:2, pages 355-372.
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Tejal Mehta, Dhaivat Parikh, Kartik Hariharan, Namdev Dhas & Viral Patel. 2021. Nanotechnology in Medicine. Nanotechnology in Medicine 109 136 .
Susana I. L. Gomes, Mónica J. B. Amorim, Suman Pokhrel, Lutz Mädler, Matteo Fasano, Eliodoro Chiavazzo, Pietro Asinari, Jaak Jänes, Kaido Tämm, Jaanus Burk & Janeck J. Scott-Fordsmand. (2021) Machine learning and materials modelling interpretation of in vivo toxicological response to TiO 2 nanoparticles library (UV and non-UV exposure) . Nanoscale 13:35, pages 14666-14678.
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Shanji Liu, Yizhou Tang, Bolu Chen, Yu Zhao, Zoraida P Aguilar, Xueying Tao & Hengyi Xu. (2021) Inhibition of testosterone synthesis induced by oral TiO2 NPs is associated with ROS-MAPK(ERK1/2)-StAR signaling pathway in SD rat. Toxicology Research 10:4, pages 937-946.
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Luciana Moreira, Carla Costa, Joana Pires, João Paulo Teixeira & Sónia Fraga. (2021) How can exposure to engineered nanomaterials influence our epigenetic code? A review of the mechanisms and molecular targets. Mutation Research/Reviews in Mutation Research 788, pages 108385.
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Mohammad Rafiq Wani & G. G. H. A. Shadab. 2021. Free Radical Biology and Environmental Toxicity. Free Radical Biology and Environmental Toxicity 131 148 .
Nicolaj S. Bischoff, Theo M. de Kok, Dick T.H.M. Sijm, Simone G. van Breda, Jacco J. Briedé, Jacqueline J.M. Castenmiller, Antoon Opperhuizen, Yolanda I. Chirino, Hubert Dirven, David Gott, Eric Houdeau, Agnes G. Oomen, Morten Poulsen, Gerhard Rogler & Henk van Loveren. (2020) Possible Adverse Effects of Food Additive E171 (Titanium Dioxide) Related to Particle Specific Human Toxicity, Including the Immune System. International Journal of Molecular Sciences 22:1, pages 207.
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Anastasios G. Papadiamantis, Jaak Jänes, Evangelos Voyiatzis, Lauri Sikk, Jaanus Burk, Peeter Burk, Andreas Tsoumanis, My Kieu Ha, Tae Hyun Yoon, Eugenia Valsami-Jones, Iseult Lynch, Georgia Melagraki, Kaido Tämm & Antreas Afantitis. (2020) Predicting Cytotoxicity of Metal Oxide Nanoparticles Using Isalos Analytics Platform. Nanomaterials 10:10, pages 2017.
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Sanaa A. Ali, Azza F. Arafa, Hanan F. Aly, Nabaweya A. Ibrahim, Mai O. Kadry, Rehab M. Abdel‐Megeed, Manal A. Hamed, Ayman A. Farghaly, Nagy S. El Regal, Ghada I. Fouad, Wagdy K. B. Khalil & Esraa A. Refaat. (2020) DNA damage and genetic aberration induced via different sized silver nanoparticles: Therapeutic approaches of Casimiroa edulis and Glycosmis pentaphylla leaves extracts . Journal of Food Biochemistry 44:10.
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Liyang Yao, Yizhou Tang, Bolu Chen, Wuding Hong, Xinyue Xu, Yang Liu, Zoraida P. Aguilar & Hengyi Xu. (2020) Oral exposure of titanium oxide nanoparticles induce ileum physical barrier dysfunction via Th1/Th2 imbalance. Environmental Toxicology 35:9, pages 982-990.
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Zhangjian Chen, Shuo Han, Shupei Zhou, Huimin Feng, Ying Liu & Guang Jia. (2020) Review of health safety aspects of titanium dioxide nanoparticles in food application. NanoImpact 18, pages 100224.
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Shanshan Zhang, Xuejun Jiang, Shuqun Cheng, Jingchuan Fan, Xia Qin, Tianxiong Wang, Yujia Zhang, Jun Zhang, Yu Qiu, Jingfu Qiu, Zhen Zou & Chengzhi Chen. (2020) Titanium dioxide nanoparticles via oral exposure leads to adverse disturbance of gut microecology and locomotor activity in adult mice. Archives of Toxicology 94:4, pages 1173-1190.
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