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Original Articles

Vascular depression: An early warning sign of frailty

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Pages 85-93 | Received 08 Feb 2012, Accepted 30 Apr 2012, Published online: 25 Jun 2012

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (8)

Ivan Aprahamian, Marcus K Borges, Denise J C Hanssen, Hans W Jeuring & Richard C Oude Voshaar. (2022) The Frail Depressed Patient: A Narrative Review on Treatment Challenges. Clinical Interventions in Aging 17, pages 979-990.
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Matthew C. Lohman, Briana Mezuk, Amanda J. Fairchild, Nicholas V. Resciniti & Anwar T. Merchant. (2022) The role of frailty in the association between depression and fall risk among older adults. Aging & Mental Health 26:9, pages 1805-1812.
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David Bickford, Ruth T. Morin, Cara Woodworth, Elizabeth Verduzco, Maryam Khan, Emily Burns, J. Craig Nelson & R. Scott Mackin. (2021) The relationship of frailty and disability with suicidal ideation in late life depression. Aging & Mental Health 25:3, pages 439-444.
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Matthew C. Lohman, Briana Mezuk & Levent Dumenci. (2017) Depression and frailty: concurrent risks for adverse health outcomes. Aging & Mental Health 21:4, pages 399-408.
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P. Naarding, E.O. Noorthoorn, T.L.A. Burm, R.C. van der Mast, A.T.F. Beekman & H.C. Comijs. (2016) Cerebrovascular involvement and clinical presentation of late-life depression, findings from the NESDO study. Aging & Mental Health 20:10, pages 1099-1106.
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Daniel Paulson & Peter A. Lichtenberg. (2015) The Paulson–Lichtenberg Frailty Index: evidence for a self-report measure of frailty. Aging & Mental Health 19:10, pages 892-901.
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Leslie Vaughan, Akeesha L Corbin & Joseph S Goveas. (2015) Depression and frailty in later life: a systematic review. Clinical Interventions in Aging 10, pages 1947-1958.
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Daniel Paulson & PeterA. Lichtenberg. (2013) Vascular depression and frailty: a compound threat to longevity among older-old women. Aging & Mental Health 17:7, pages 901-910.
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Articles from other publishers (27)

Ni Sang, Bo-Han Li, Meng-Yao Zhang, Meng Wei, Ruo-Xuan Fang, Wen-Jing Liu, Li-E Huang, Jing Zhang & Guo-Cui Wu. (2023) Bidirectional causal relationship between depression and frailty: a univariate and multivariate Mendelian randomisation study. Age and Ageing 52:7.
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Matheus Lucena Germano, Cristiano dos Santos Gomes, Juliana Fernandes de Souza Barbosa, Nailton José Neto, Daniele Sirineu Pereira, Tamer Ahmed, Carmen Lucia Curcio Borrero & Ricardo Oliveira Guerra. (2023) Allostatic load and physical performance in older adults: Findings from the International Mobility in Aging Study (IMIAS). Archives of Gerontology and Geriatrics 109, pages 104961.
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Ilex Beltran-Najera, Andrea Mustafa, Desmond Warren, Zach Salling, Maria Misiura, Steven Paul Woods & Vonetta M. Dotson. (2023) Elevated frequency and everyday functioning implications of vascular depression in persons with HIV disease. Journal of Psychiatric Research 160, pages 78-85.
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Weibo Ma, Bei Wu, Xiaoqin Gao & Renyao Zhong. (2022) Association between frailty and cognitive function in older Chinese people: A moderated mediation of social relationships and depressive symptoms. Journal of Affective Disorders 316, pages 223-232.
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Priscila Marconcin, Sharon Barak, Gerson Ferrari, Élvio R. Gouveia, Marcelo de Maio Nascimento, Renata Willig, Margarida Varela & Adilson Marques. (2022) Prevalence of Frailty and Its Association with Depressive Symptoms among European Older Adults from 17 Countries: A 5-Year Longitudinal Study. International Journal of Environmental Research and Public Health 19:21, pages 14055.
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Ece Kocagoncu, David Nesbitt, Tina Emery, Laura E. Hughes, Richard N. Henson & James B. Rowe. (2022) Neurophysiological and Brain Structural Markers of Cognitive Frailty Differ from Alzheimer's Disease. The Journal of Neuroscience 42:7, pages 1362-1373.
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Limin Cao, Yuhan Zhou, Huiyuan Liu, Mengyuan Shi, Yingliang Wei & Yang Xia. (2022) Bidirectional Longitudinal Study of Frailty and Depressive Symptoms Among Older Chinese Adults. Frontiers in Aging Neuroscience 14.
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Takaaki Ikeda & Toru Tsuboya. (2022) Effects of changes in depressive symptoms on handgrip strength in later life: A four-year longitudinal study in England. Journal of Affective Disorders 299, pages 67-72.
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M. K. Borges, C. V. Romanini, N. A. Lima, M. Petrella, D. L. da Costa, V. N. An, B. N. Aguirre, J. R. Galdeano, I. C. Fernandes, J. F. Cecato, E. C. Robello, R. C. Oude Voshaar & I. Aprahamian. (2021) Longitudinal Association between Late-Life Depression (LLD) and Frailty: Findings from a Prospective Cohort Study (MiMiCS-FRAIL). The journal of nutrition, health & aging 25:7, pages 895-902.
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Xuehui Wang & Kaijun Shen. (2021) The Reciprocal Relationship between Frailty and Depressive Symptoms among Older Adults in Rural China: A Cross-Lag Analysis. Healthcare 9:5, pages 593.
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André Hajek, Christian Brettschneider, Tina Mallon, Dagmar Lühmann, Anke Oey, Birgitt Wiese, Siegfried Weyerer, Jochen Werle, Angela Fuchs, Michael Pentzek, Susanne Röhr, Melanie Luppa, Edelgard Mösch, Dagmar Weeg, Kathrin Heser, Michael Wagner, Martin Scherer, Wolfgang Maier, Steffi G. Riedel-Heller & Hans-Helmut König. (2021) Depressive Symptoms and Frailty Among the Oldest Old: Evidence From a Multicenter Prospective Study. Journal of the American Medical Directors Association 22:3, pages 577-582.e2.
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Massimo Bartoli, Sara Palermo, Giuseppina Elena Cipriani & Martina Amanzio. (2020) A Possible Association Between Executive Dysfunction and Frailty in Patients With Neurocognitive Disorders. Frontiers in Psychology 11.
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Na Zhang, Guo-Ping Shi, Yong Wang, Xue-Feng Chu, Zheng-Dong Wang, Jian-Ming Shi, Jiang-Hong Guo, Yu-Chen Wang, Shun Yao, Xiao-Yan Jiang, Yin-Sheng Zhu & Xiao-Feng Wang. (2019) Depressive symptoms are associated with incident frailty in a Chinese population: the Rugao Longevity and Aging Study. Aging Clinical and Experimental Research 32:11, pages 2297-2302.
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Sara N Rushia, Al Amira Safa Shehab, Jeffrey N Motter, Dakota A Egglefield, Sophie Schiff, Joel R Sneed & Ernst Garcon. (2020) Vascular depression for radiology: A review of the construct, methodology, and diagnosis. World Journal of Radiology 12:5, pages 48-67.
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Patrick J. Brown. (2019) Commentary: Depression and Incidence of Frailty in Older People From Six Latin American Countries by Prina et al.. The American Journal of Geriatric Psychiatry 27:10, pages 1080-1082.
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Francesco Panza, Madia Lozupone, Vincenzo Solfrizzi, Rodolfo Sardone, Vittorio Dibello, Luca Di Lena, Francesca D’Urso, Roberta Stallone, Massimo Petruzzi, Gianluigi Giannelli, Nicola Quaranta, Antonello Bellomo, Antonio Greco, Antonio Daniele, Davide Seripa & Giancarlo Logroscino. (2018) Different Cognitive Frailty Models and Health- and Cognitive-related Outcomes in Older Age: From Epidemiology to Prevention. Journal of Alzheimer's Disease 62:3, pages 993-1012.
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Martina Amanzio, Sara Palermo, Milena Zucca, Rosalba Rosato, Elisa Rubino, Daniela Leotta, Massimo Bartoli & Innocenzo Rainero. (2017) Neuropsychological Correlates of Pre-Frailty in Neurocognitive Disorders: A Possible Role for Metacognitive Dysfunction and Mood Changes. Frontiers in Medicine 4.
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Bertrand Fougère, Julien Delrieu, Natalia del Campo, Gaëlle Soriano, Sandrine Sourdet & Bruno Vellas. (2017) RETRACTED: Cognitive Frailty: Mechanisms, Tools to Measure, Prevention and Controversy. Clinics in Geriatric Medicine 33:3, pages 339-355.
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Pinar Soysal, Nicola Veronese, Trevor Thompson, Kai G. Kahl, Brisa S. Fernandes, A. Matthew Prina, Marco Solmi, Patricia Schofield, Ai Koyanagi, Ping-Tao Tseng, Pao-Yao Lin, Che-Sheng Chu, Theodore D. Cosco, Matteo Cesari, Andre F. Carvalho & Brendon Stubbs. (2017) Relationship between depression and frailty in older adults: A systematic review and meta-analysis. Ageing Research Reviews 36, pages 78-87.
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Ma Dolores Serrano, Margarita Garrido, Rosa Ma Fuentes, Ma José Simón & Ma José Díaz. (2017) The impact of biological frailty syndrome on quality of life of nursing home residents. Applied Nursing Research 35, pages 112-117.
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Linda Lee, Tejal Patel, Loretta M. Hillier, Niraj Maulkhan, Karen Slonim & Andrew Costa. (2017) Identifying frailty in primary care: A systematic review. Geriatrics & Gerontology International.
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Guy G. Potter, Douglas R. McQuoid, Heather E. Whitson & David C. Steffens. (2016) Physical frailty in late-life depression is associated with deficits in speed-dependent executive functions. International Journal of Geriatric Psychiatry 31:5, pages 466-474.
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Celia F. Hybels, Carl F. Pieper, Martha E. Payne & David C. Steffens. (2016) Late-life Depression Modifies the Association Between Cerebral White Matter Hyperintensities and Functional Decline Among Older Adults. The American Journal of Geriatric Psychiatry 24:1, pages 42-49.
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Francesco PanzaVincenzo SolfrizziMaria Rosaria BarulliAndrea SantamatoDavide SeripaAlberto PilottoGiancarlo Logroscino. (2015) Cognitive Frailty: A Systematic Review of Epidemiological and Neurobiological Evidence of an Age-Related Clinical Condition. Rejuvenation Research 18:5, pages 389-412.
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Francesco Panza, Davide Seripa, Vincenzo Solfrizzi, Rosanna Tortelli, Antonio Greco, Alberto Pilotto & Giancarlo Logroscino. (2015) Targeting Cognitive Frailty: Clinical and Neurobiological Roadmap for a Single Complex Phenotype. Journal of Alzheimer's Disease 47:4, pages 793-813.
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Deirdre A. Robertson, George M. Savva, Robert F. Coen & Rose-Anne Kenny. (2014) Cognitive Function in the Prefrailty and Frailty Syndrome. Journal of the American Geriatrics Society 62:11, pages 2118-2124.
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Matthew Lohman, Levent Dumenci & Briana Mezuk. (2014) Sex Differences in the Construct Overlap of Frailty and Depression: Evidence from the Health and Retirement Study. Journal of the American Geriatrics Society 62:3, pages 500-505.
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