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Aging & Mental Health Volume 17, 2013 - Issue 1
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Original Articles

The effects of abrupt antipsychotic discontinuation in cognitively impaired older persons: A pilot study

M. Azermai Division of Clinical Pharmacology, Heymans Institute of Pharmacology, Ghent University, Ghent, BelgiumCorrespondence[email protected]
,
M. Petrovic Division of Clinical Pharmacology, Heymans Institute of Pharmacology, Ghent University, Ghent, Belgium; Service of Geriatrics, Ghent University Hospital, Ghent, Belgium
,
S. Engelborghs Department of Biomedical Sciences, Institute Born-Bunge, University of Antwerp, Antwerp, Belgium; Reference Center for Biological Markers of Dementia, University of Antwerp, Antwerp, Belgium; Department of Neurology and Memory Clinic, Hospital Network Antwerp Middelheim and Hoge Beuken, Antwerp, Belgium
,
M.M. Elseviers Division of Clinical Pharmacology, Heymans Institute of Pharmacology, Ghent University, Ghent, Belgium; Department of Nursing Sciences and Midwifery, University of Antwerp, Antwerp, Belgium
,
S. Van der Mussele Department of Nursing Sciences and Midwifery, University of Antwerp, Antwerp, Belgium
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H. Debruyne Psychiatric Center Dr Guislain, Ghent, Belgium
,
L. Van Bortel Division of Clinical Pharmacology, Heymans Institute of Pharmacology, Ghent University, Ghent, Belgium
&
R.H. Vander Stichele Division of Clinical Pharmacology, Heymans Institute of Pharmacology, Ghent University, Ghent, Belgium
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Pages 125-132 | Received 26 Mar 2012, Accepted 12 Jul 2012, Published online: 28 Aug 2012

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Benedetta Milanini, Stephanie Catella, Brandon Perkovich, Pardis Esmaeili-Firidouni, Lauren Wendelken, Robert Paul, Meredith Greene, Robin Ketelle & Victor Valcour. (2017) Psychiatric symptom burden in older people living with HIV with and without cognitive impairment: the UCSF HIV over 60 cohort study. AIDS Care 29:9, pages 1178-1185.
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Prasad S. Nishtala, Mohammed Saji Salahudeen & Sarah N. Hilmer. (2016) Anticholinergics: theoretical and clinical overview. Expert Opinion on Drug Safety 15:6, pages 753-768.
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Majda Azermai, Robert R.H. Vander Stichele, Luc M. Van Bortel & Monique M. Elseviers. (2014) Barriers to antipsychotic discontinuation in nursing homes: an exploratory study. Aging & Mental Health 18:3, pages 346-353.
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Carol Dillon, Cecilia M Serrano, Diego Castro, Patricio Perez Leguizamón, Silvina L Heisecke & Fernando E Taragano. (2013) Behavioral symptoms related to cognitive impairment. Neuropsychiatric Disease and Treatment 9, pages 1443-1455.
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Articles from other publishers (11)

Mario F. Mendez. (2022) Managing the Behavioral and Psychological Symptoms of Dementia. Current Treatment Options in Neurology 24:5, pages 183-201.
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Lasse Brandt, Tom Bschor, Jonathan Henssler, Martin Müller, Alkomiet Hasan, Andreas Heinz & Stefan Gutwinski. (2020) Antipsychotic Withdrawal Symptoms: A Systematic Review and Meta-Analysis. Frontiers in Psychiatry 11.
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Sven Schmiedl, David Peters, Oliver Schmalz, Anke Mielke, Tanja Rossmanith, Shirin Diop, Martina Piefke, Petra Thürmann & Achim Schmidtko. (2019) Loxapine for Treatment of Patients With Refractory, Chemotherapy-Induced Neuropathic Pain: A Prematurely Terminated Pilot Study Showing Efficacy But Limited Tolerability. Frontiers in Pharmacology 10.
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Ellen Van Leeuwen, Mirko Petrovic, Mieke L van Driel, An IM De Sutter, Robert Vander Stichele, Tom Declercq & Thierry Christiaens. (2018) Withdrawal versus continuation of long-term antipsychotic drug use for behavioural and psychological symptoms in older people with dementia. Cochrane Database of Systematic Reviews 2022:4.
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A. Geeraerts, T. Dilles, V. Foulon, H. Habraken, M. Petrovic, G. Strauven, J. Tournoy, O. Vandeput, A. Wertelaers, E. Vlaeyen & K. Milisen. (2017) Ontwikkeling van algoritmes voor oordeelkundig gebruik van psychofarmaca bij ouderen met verhoogd valrisicoThe development of clinical practice algorithms for the appropriate use of psychotropic drugs in older persons with high risk of falls. Tijdschrift voor Gerontologie en Geriatrie 48:5, pages 195-202.
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Henry C. Ndukwe & Prasad S. Nishtala. (2016) Time-to-First Discontinuation, Adherence and Persistence in New Users of Second-Generation Antipsychotics. Journal of Clinical Psychopharmacology 36:6, pages 649-657.
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Amy T. Page, Rhonda M. Clifford, Kathleen Potter, Darren Schwartz & Christopher D. Etherton‐Beer. (2016) The feasibility and effect of deprescribing in older adults on mortality and health: a systematic review and meta‐analysis. British Journal of Clinical Pharmacology 82:3, pages 583-623.
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John R. Bowblis, Judith A. Lucas & Christopher S. Brunt. (2015) The Effects of Antipsychotic Quality Reporting on Antipsychotic and Psychoactive Medication Use. Health Services Research 50:4, pages 1069-1087.
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J. Ngo & J. M. Holroyd-Leduc. (2014) Systematic review of recent dementia practice guidelines. Age and Ageing 44:1, pages 25-33.
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Yves Rolland, Barbara Resnick, Paul R. Katz, Milta O. Little, Joseph G. Ouslander, Alice Bonner, Carol R. Geary, Karen L. Schumacher, Sarah Thompson, Finbarr C. Martin, Joachim Wilbers, Franziska Zúñiga, D. Ausserhofer, R. Schwendimann, S. Schüssler, Theo Dassen, Christa Lohrmann, Cari Levy, Emily Whitfield, Philipe de Souto Barreto, Christopher Etherton-Beer, Tinne Dilles, Majda Azermai, Jolyce Bourgeois, Martin Orrell, George T. Grossberg, Hélène Kergoat, David R. Thomas, Jan Visschedijk, Stephanie J.C. Taylor, Yvonne S. Handajani, Nelly T. Widjaja, Yuda Turana, Marilyn J. Rantz, Marjorie Skubic & John E. Morley. (2014) Nursing Home Research: The First International Association of Gerontology and Geriatrics (IAGG) Research Conference. Journal of the American Medical Directors Association 15:5, pages 313-325.
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Majda AzermaiJolyce Bourgeois, Annemie Somers & Mirko Petrovic. (2013) Inappropriate use of psychotropic drugs in older individuals: implications for practice. Aging Health 9:3, pages 255-264.
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