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Aging & Mental Health Volume 17, 2013 - Issue 5
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Original Articles

Olfaction and apathy in Alzheimer's disease, mild cognitive impairment, and healthy older adults

Sarah C. Seligman Department of Psychology, Temple University, Philadelphia, PA, USA
,
Vidyulata Kamath Department of Psychiatry, University of Pennsylvania, Philadelphia, PA, USA; Smell and Taste Center, Department of Otorhinolaryngology: Head & Neck Surgery, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA
,
Tania Giovannetti Department of Psychology, Temple University, Philadelphia, PA, USA
,
Steven E. Arnold Department of Psychiatry, University of Pennsylvania, Philadelphia, PA, USA; Smell and Taste Center, Department of Otorhinolaryngology: Head & Neck Surgery, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA; Alzheimer's Disease Core Center, University of Pennsylvania, Philadelphia, PA, USA; Department of Neurology, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA
&
Paul J. Moberg Department of Psychiatry, University of Pennsylvania, Philadelphia, PA, USA; Smell and Taste Center, Department of Otorhinolaryngology: Head & Neck Surgery, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA; Alzheimer's Disease Core Center, University of Pennsylvania, Philadelphia, PA, USA; Department of Neurology, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA
Pages 564-570 | Received 28 Aug 2012, Accepted 11 Jan 2013, Published online: 12 Feb 2013

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Yong-ming Zou, Da Lu, Li-ping Liu, Hui-hong Zhang & Yu-ying Zhou. (2016) Olfactory dysfunction in Alzheimer’s disease. Neuropsychiatric Disease and Treatment 12, pages 869-875.
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Articles from other publishers (41)

Benoît Jobin, Benjamin Boller & Johannes Frasnelli. (2023) Smaller grey matter volume in the central olfactory system in mild cognitive impairment. Experimental Gerontology 183, pages 112325.
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Silin Liu, Zhihui Jiang, Jing Zhao, Zhensheng Li, Ruixin Li, Yunyi Qiu & Hua Peng. (2023) Disparity of smell tests in Alzheimer’s disease and other neurodegenerative disorders: a systematic review and meta-analysis. Frontiers in Aging Neuroscience 15.
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Emre Hari, Elif Kurt, Cigdem Ulasoglu-Yildiz, Ali Bayram, Başar Bilgic, Tamer Demiralp & Hakan Gurvit. (2023) Morphometric analysis of medial temporal lobe subregions in Alzheimer's disease using high-resolution MRI. Brain Structure and Function.
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Helena Dolphin, Adam H. Dyer, Cathy McHale, Sean O’Dowd & Sean P. Kennelly. (2023) An Update on Apathy in Alzheimer’s Disease. Geriatrics 8:4, pages 75.
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Carla Masala, Paolo Solla & Francesco Loy. (2023) Gender-Related Differences in the Correlation between Odor Threshold, Discrimination, Identification, and Cognitive Reserve Index in Healthy Subjects. Biology 12:4, pages 586.
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Mousumi Laha, Amit Konar & Atulya K. Nagar. (2023) Olfactory Perceptual-Ability Assessment by Near-Infrared Spectroscopy Using Vertical-Slice Based Fuzzy Reasoning. IEEE Access 11, pages 17779-17792.
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David C. Steffens, Mario Fahed, Kevin J. Manning & Lihong Wang. (2022) The neurobiology of apathy in depression and neurocognitive impairment in older adults: a review of epidemiological, clinical, neuropsychological and biological research. Translational Psychiatry 12:1.
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Zara M. Patel, Eric H. Holbrook, Justin H. Turner, Nithin D. Adappa, Mark W. Albers, Aytug Altundag, Simone Appenzeller, Richard M. Costanzo, Ilona Croy, Greg E. Davis, Puya Dehgani‐Mobaraki, Richard L. Doty, Valerie B. Duffy, Bradley J. Goldstein, David A. Gudis, Antje Haehner, Thomas S. Higgins, Claire Hopkins, Caroline Huart, Thomas Hummel, Kawinyarat Jitaroon, Robert C. Kern, Ashoke R. Khanwalkar, Masayoshi Kobayashi, Kenji Kondo, Andrew P. Lane, Matt Lechner, Donald A. Leopold, Joshua M. Levy, Michael J. Marmura, Lisha Mclelland, Takaki Miwa, Paul J. Moberg, Christian A. Mueller, Sagar U. Nigwekar, Erin K. O'Brien, Teodor G. Paunescu, Robert Pellegrino, Carl Philpott, Jayant M. Pinto, Evan R. Reiter, David R. Roalf, Nicholas R. Rowan, Rodney J. Schlosser, James Schwob, Allen M. Seiden, Timothy L. Smith, Zachary M. Soler, Leigh Sowerby, Bruce K. Tan, Andrew Thamboo, Bozena Wrobel & Carol H. Yan. (2022) International consensus statement on allergy and rhinology: Olfaction. International Forum of Allergy & Rhinology 12:4, pages 327-680.
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Si Zhang, Ben Chen, Xiaomei Zhong, Min Zhang, Qiang Wang, Zhangying Wu, Le Hou, Huarong Zhou, Xinru Chen, Meiling Liu, Mingfeng Yang, Gaohong Lin, Thomas Hummel & Yuping Ning. (2022) Interactive Effects of Agitation and Cognitive Impairment on Odor Identification in Patients With Late-Life Depression. Frontiers in Psychiatry 13.
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Moyra E. Mortby, Lawrence Adler, Luis Agüera-Ortiz, Daniel R. Bateman, Henry Brodaty, Marc Cantillon, Yonas E. Geda, Zahinoor Ismail, Krista L. Lanctôt, Gad A. Marshall, Prasad R. Padala, Antonios Politis, Paul B. Rosenberg, Kostas Siarkos, David L. Sultzer & Christos Theleritis. (2022) Apathy as a Treatment Target in Alzheimer's Disease: Implications for Clinical Trials. The American Journal of Geriatric Psychiatry 30:2, pages 119-147.
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Qiang Wang, Ben Chen, Xiaomei Zhong, Huarong Zhou, Min Zhang, Naikeng Mai, Zhangying Wu, Xinru Chen, Mingfeng Yang, Si Zhang, Gaohong lin, Thomas Hummel & Yuping Ning. (2022) Neuropsychiatric Symptoms Mediated the Relationship Between Odor Identification and Cognition in Alzheimer's Disease Spectrum: A Structural Equation Model Analysis. Frontiers in Aging Neuroscience 13.
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Woojung Lee, Shelly L. Gray, Douglas Barthold, Donovan T. Maust & Zachary A. Marcum. (2020) Association Between Informant-Reported Sleep Disturbance and Incident Dementia: An Analysis of the National Alzheimer’s Coordinating Center Uniform Data Set. Journal of Applied Gerontology 41:1, pages 285-294.
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Franziska Ottens, André Franz & Thorsten Hoppe. (2021) Build-UPS and break-downs: metabolism impacts on proteostasis and aging. Cell Death & Differentiation 28:2, pages 505-521.
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Shu-yang Yu, Teng-hong Lian, Peng Guo, Li-xia Li, Du-yu Ding, Dan-ning Li, Li Liu, Hui Zhao, Yang Hu, Li-jun Zuo, Jun-hua Gao, Qiu-jin Yu, Zhao Jin, Rui-dan Wang, Rong-yan Zhu, Xiao-min Wang & Wei Zhang. (2020) Correlations of apathy with clinical symptoms of Alzheimer’s disease and olfactory dysfunctions: a cross-sectional study. BMC Neurology 20:1.
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Ding Ding, Zhenxu Xiao, Xiaoniu Liang, Wanqing Wu, Qianhua Zhao & Yang Cao. (2020) Predictive Value of Odor Identification for Incident Dementia: The Shanghai Aging Study. Frontiers in Aging Neuroscience 12.
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Fengyi Liang. (2020) Sustentacular Cell Enwrapment of Olfactory Receptor Neuronal Dendrites: An Update. Genes 11:5, pages 493.
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Chama Belkhiria, Rodrigo C. Vergara, Simón San Martin, Alexis Leiva, Melissa Martinez, Bruno Marcenaro, Maricarmen Andrade, Paul H. Delano & Carolina Delgado. (2020) Insula and Amygdala Atrophy Are Associated With Functional Impairment in Subjects With Presbycusis. Frontiers in Aging Neuroscience 12.
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Maryam Yahiaoui-Doktor, Tobias Luck, Steffi G. Riedel-Heller, Markus Loeffler, Kerstin Wirkner & Christoph Engel. (2019) Olfactory function is associated with cognitive performance: results from the population-based LIFE-Adult-Study. Alzheimer's Research & Therapy 11:1.
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Vidyulata Kamath, Grace-Anna S. Chaney, Jonathan DeRight & Chiadi U. Onyike. (2018) A meta-analysis of neuropsychological, social cognitive, and olfactory functioning in the behavioral and language variants of frontotemporal dementia. Psychological Medicine 49:16, pages 2669-2680.
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Kamonwan Suebsaen, Benjamas Suksatit, Nattapong Kanha & Thunnop Laokuldilok. (2019) Instrumental characterization of banana dessert gels for the elderly with dysphagia. Food Bioscience 32, pages 100477.
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Hui Zhang, Dongxu Ji, Jianzhong Yin, Zhiyun Wang, Yuying Zhou, Hongyan Ni & Yawu Liu. (2019) Olfactory fMRI Activation Pattern Across Different Concentrations Changes in Alzheimer’s Disease. Frontiers in Neuroscience 13.
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Teng-Hong Lian, Wan-Lin Zhu, Shao-Wu Li, Ya-Ou Liu, Peng Guo, Li-Jun Zuo, Yang Hu, Shu-Yang Yu, Li-Xia Li, Zhao Jin, Qiu-Jin Yu, Rui-Dan Wang & Wei Zhang. (2019) Clinical, Structural, and Neuropathological Features of Olfactory Dysfunction in Patients with Alzheimer’s Disease. Journal of Alzheimer's Disease 70:2, pages 413-423.
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Maren de Moraes e Silva, Pilar Bueno Siqueira Mercer, Maria Carolina Zavagna Witt & Renata Ramina Pessoa. (2018) Olfactory dysfunction in Alzheimer’s disease Systematic review and meta-analysis. Dementia & Neuropsychologia 12:2, pages 123-132.
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Qiujin Yu, Peng Guo, Danning Li, Lijun Zuo, Tenghong Lian, Shuyang Yu, Yang Hu, Li Liu, Zhao Jin, Ruidan Wang, Yingshan Piao, Lixia Li, Xiaomin Wang & Wei Zhang. (2018) Olfactory Dysfunction and Its Relationship with Clinical Symptoms of Alzheimer Disease. Aging and disease 9:6, pages 1084.
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