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The European Journal of Contraception & Reproductive Health Care Volume 5, 2000 - Issue 1
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Original Article

Inhibition of ovulation by a novel progestogen (drospirenone) alone or in combination with ethinylestradiol

P. Rosenbaum Universitätskliniken des Saarlandes, Frauenklinik und Poliklinik, Homburg, Germany
,
Professor W. Schmidt Universitätskliniken des Saarlandes, Frauenklinik und Poliklinik, Homburg, Germany
,
F. M. Helmerhorst Leiden University Medical Center, Leiden, The Netherlands
,
W. Wuttke Frauenklinik, Georg-August-Universität Göttingen, Göttingen, Germany
,
W. Rossmanith Frauenklinik des Diakonissenkrankenhauses, Karlsruhe, Germany
,
F. Freundl Stadtisches Krankenhaus D-Benrath Frauenklinik, Düsseldorf, Germany
,
K. Thomas Faculty of Medicine, Brussels, Belgium
,
M. Grillo Klinikum der Christian-Albrechts-Universität zu Kiel, Kiel, Germany
,
A. Wolf Praxisklinik, Frauenstrasse, Ulm, Germany
&
R. Heithecker Schering AG, Clinical Development, Fertility Control, Berlin, Germany
 show all
Pages 16-24 | Accepted 24 Mar 2000, Published online: 06 Jul 2009

Citations (35)

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Maria Chiara Del Savio, Riccardo De Fata, Fabio Facchinetti & Giovanni Grandi. (2020) Drospirenone 4 mg-only pill (DOP) in 24+4 regimen: a new option for oral contraception. Expert Review of Clinical Pharmacology 13:7, pages 685-694.
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Carlo Bastianelli, Manuela Farris, Elena Rosato, Ivo Brosens & Giuseppe Benagiano. (2018) Pharmacodynamics of combined estrogen-progestin oral contraceptives 3. Inhibition of ovulation. Expert Review of Clinical Pharmacology 11:11, pages 1085-1098.
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Andrea J Rapkin & Sharon A Winer. (2007) Drospirenone: a novel progestin. Expert Opinion on Pharmacotherapy 8:7, pages 989-999.
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W. H. K. Oelkers. (2005) Drospirenone in combination with estrogens: for contraception and hormone replacement therapy. Climacteric 8:sup3, pages 19-27.
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J. Endrikat, C. Gerlinger, K. Plettig, J. Wessel, W. Schmidt, G. Grubb & B. Düsterberg. (2003) A meta-analysis on the correlation between ovarian activity and the incidence of intermenstrual bleeding during low-dose oral contraceptive use. Gynecological Endocrinology 17:2, pages 107-114.
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J.-M. Foidart, W. Wuttke, G. M. Bouw, C. Gerlinger & R. Heithecker. (2000) A comparative investigation of contraceptive reliability, cycle control and tolerance of two monophasic oral contraceptives containing either drospirenone or desogestrel. The European Journal of Contraception & Reproductive Health Care 5:2, pages 124-134.
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J. Huber, J. M. Foidart, W. Wuttke, G. S. Merki-Feld, H. S. The, C. Gerlinger, I. Schellschrmdt & R. Heithecker. (2000) Efficacy and tolerability of a monophasic oral contraceptive containing ethinylestradiol and drospirenone. The European Journal of Contraception & Reproductive Health Care 5:1, pages 25-34.
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Articles from other publishers (28)

Javier Peña, Iria González-Mariño & José L. Pérez Pavón. (2023) Ultrasound-Assisted Extraction, Followed by Gas Chromatography–Mass Spectrometry for the Simultaneous Quantification of Ethinyl Estradiol and Drospirenone in Contraceptive Formulations. Molecules 28:13, pages 4978.
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Alexandra Wollum, Carmela Zuniga, Kelly Blanchard & Stephanie Teal. (2023) A commentary on progestin-only pills and the “three-hour window” guidelines: Timing of ingestion and mechanisms of action. Contraception 122, pages 109978.
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Pedro-Antonio Regidor, Anna Mueller & Manuela Mayr. (2023) Pharmacological and metabolic effects of drospirenone as a progestin-only pill compared to combined formulations with estrogen. Women's Health 19, pages 174550572211473.
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Alvaro Monterrosa-Castro, Velia Redondo-Mendoza & Angelica Monterrosa-Blanco. (2021) Current Knowledge of Progestin-Only Pills. Electronic Journal of General Medicine 18:6, pages em320.
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Trond Viggo Grøntvedt, Nicholas M. Grebe, Leif Edward Ottesen Kennair & Steven W. Gangestad. (2017) Estrogenic and progestogenic effects of hormonal contraceptives in relation to sexual behavior: insights into extended sexuality. Evolution and Human Behavior 38:3, pages 283-292.
Crossref
Maria F Gallo, Laureen M Lopez, David A Grimes, Florence Carayon, Kenneth F Schulz & Frans M Helmerhorst. (2014) Combination contraceptives: effects on weight. Cochrane Database of Systematic Reviews 2014:1.
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David H Barad, Ann Kim, Hala Kubba, Andrea Weghofer & Norbert Gleicher. (2013) Does hormonal contraception prior to in vitro fertilization (IVF) negatively affect oocyte yields? - A pilot study. Reproductive Biology and Endocrinology 11:1, pages 28.
Crossref
Franca Fruzzetti. (2012) Beyaz®: An Oral Contraceptive Fortified with Folate. Women's Health 8:1, pages 13-19.
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Jan Endrikat, Christoph Gerlinger, Stephanie Richard, Peter Rosenbaum & Bernd Düsterberg. (2011) Ovulation inhibition doses of progestins: a systematic review of the available literature and of marketed preparations worldwide. Contraception 84:6, pages 549-557.
Crossref
Maria F Gallo, Kavita Nanda, David A Grimes, Laureen M Lopez & Kenneth F Schulz. 1996. Cochrane Database of Systematic Reviews. Cochrane Database of Systematic Reviews.
Rogério Bonassi Machado, Luciano de Melo Pompei, Arícia Galvão Giribela & Cassiana Galvão Giribela. (2011) Drospirenone/Ethinylestradiol: A Review on Efficacy and Noncontraceptive Benefits. Women's Health 7:1, pages 19-30.
Crossref
C. Quéreux, É. Raimond & O. Graesslin. (2010) WITHDRAWN: Contraception orale et non orale: actualités. La Revue Sage-Femme.
Crossref
Maria F Gallo, Kavita Nanda, David A Grimes, Laureen M Lopez & Kenneth F Schulz. 1996. Cochrane Database of Systematic Reviews. Cochrane Database of Systematic Reviews.
Ian Milsom & Tjeerd Korver. (2008) Ovulation incidence with oral contraceptives: a literature review. Journal of Family Planning and Reproductive Health Care 34:4, pages 237-246.
Crossref
Faustino R. Pérez-López. (2008) Clinical experiences with drospirenone: From reproductive to postmenopausal years. Maturitas 60:2, pages 78-91.
Crossref
Andrea J RapkinMichelle McDonaldSharon A Winer. (2016) Ethinyl Estradiol/Drospirenone for the Treatment of the Emotional and Physical Symptoms of Premenstrual Dysphoric Disorder. Women's Health 3:4, pages 395-408.
Crossref
Madhavi Mallareddy, Vladimir Hanes & William B White. (2007) Drospirenone, a New Progestogen, for Postmenopausal Women with Hypertension. Drugs & Aging 24:6, pages 453-466.
Crossref
Martin Sillem. (2016) Yasminelle®: A New Low-Dose Combined Oral Contraceptive Containing Drospirenone. Women's Health 2:4, pages 551-559.
Crossref
Maria F Gallo, Laureen M Lopez, David A Grimes, Kenneth F Schulz & Frans M Helmerhorst. 1996. Cochrane Database of Systematic Reviews. Cochrane Database of Systematic Reviews.
O. Graesslin & C. Quereux. (2005) Mise au point sur la contraception. Journal de Gynécologie Obstétrique et Biologie de la Reproduction 34:6, pages 529-556.
Crossref
Tjeerd Korver, Christine Klipping, Doris Heger-Mahn, Ingrid Duijkers, Gonnie van Osta & Thom Dieben. (2005) Maintenance of ovulation inhibition with the 75-μg desogestrel-only contraceptive pill (Cerazette®) after scheduled 12-h delays in tablet intake. Contraception 71:1, pages 8-13.
Crossref
Wolfgang Oelkers. (2004) Drospirenone, a progestogen with antimineralocorticoid properties: a short review. Molecular and Cellular Endocrinology 217:1-2, pages 255-261.
Crossref
Maria F. Gallo, David A. Grimes, Kenneth F. Schulz & Frans M. Helmerhorst. (2004) Combination Estrogen–Progestin Contraceptives and Body Weight: Systematic Review of Randomized Controlled Trials. Obstetrics & Gynecology 103:2, pages 359-373.
Crossref
Walter Elger, Sybille Beier, Kunhard Pollow, Robert Garfield, Shao Qing Shi & Alexander Hillisch. (2003) Conception and pharmacodynamic profile of drospirenone. Steroids 68:10-13, pages 891-905.
Crossref
Paul Davies, Christopher Fursdon-Davies & Margaret CP Rees. (2016) Progestogens for Menstrual Migraine. British Menopause Society Journal 9:3, pages 134-134.
Crossref
Patricia Aikins Murphy. (2003) New Methods of Hormonal Contraception. The Nurse Practitioner 28:2, pages 11-21.
Crossref
Frank Lüdicke, Elisabeth Johannisson, Frans M Helmerhorst, Aldo Campana, Jean-Michel Foidart & Renate Heithecker. (2001) Effect of a combined oral contraceptive containing 3 mg of drospirenone and 30 μg of ethinyl estradiol on the human endometrium. Fertility and Sterility 76:1, pages 102-107.
Crossref
Rolf Krattenmacher. (2000) Drospirenone: pharmacology and pharmacokinetics of a unique progestogen. Contraception 62:1, pages 29-38.
Crossref

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