Advanced search
Publication Cover
The Aging Male Volume 8, 2005 - Issue 3-4
Submit an article Journal homepage
4,837
Views
26
CrossRef citations to date
0
Altmetric
Original

Weapons of penile smooth muscle destruction: Androgen deficiency promotes accumulation of adipocytes in the corpus cavernosum

A. M. Traish Director Department of Biochemistry,; The Institute for Sexual Medicine, Department of Urology, Boston University School of Medicine, Boston, Massachusetts, USACorrespondence[email protected]
&
N. Kim The Institute for Sexual Medicine, Department of Urology, Boston University School of Medicine, Boston, Massachusetts, USA
Pages 141-146 | Published online: 06 Jul 2009

Citations (26)

Keep up to date with the latest research on this topic with citation updates for this article.

Subscribe to citation updates

Read on this site (1)

Michał Rabijewski, Lucyna Papierska, Jarosław Kozakowski & Wojciech Zgliczyński. (2012) The high prevalence of testosterone deficiency in population of Polish men over 65 years with erectile dysfunctions. The Aging Male 15:4, pages 258-262.
Read now

Articles from other publishers (25)

Hak Myong Choe, Kai Gao, Hyo Jin Paek, Xin-Yue Liu, Zhou-Yan Li, Biao-Hu Quan & Xi-Jun Yin. (2022) Silencing myostatin increases area fraction of smooth muscle in the corpus cavernosum of pigs. Animal Reproduction Science 247, pages 107077.
Crossref
Abdulmaged M. Traish. (2022) Accumulation of Adipocytes in Penile Corpus Cavernosum May Contribute to Venous Leakage and Veno-Occlusive Dysfunction in Patients with Testosterone Deficiency and Erectile Dysfunction. Androgens: Clinical Research and Therapeutics 3:1, pages 125-132.
Crossref
Thomas Van den Broeck, Mohammad Ayodhia Soebadi, Annelies Falter, Lore Raets, Jolien Duponselle, Joline Lootsma, Alexander Heintz, Uchelly Philtjens, Lien Hofkens, Arantxa Gonzalez-Viedma, Karel Driesen, Peter Sandner, Maarten Albersen, Bert Brône & Koenraad Van Renterghem. (2020) Testosterone Induces Relaxation of Human Corpus Cavernosum Tissue of Patients With Erectile Dysfunction. Sexual Medicine 8:1, pages 114-119.
Crossref
Yang Chen, Jie Li, Jinling Liao, Yanling Hu, Haiying Zhang, Xiaobo Yang, Qiuyan Wang, Zengnan Mo & Jiwen Cheng. (2018) Potential Protective Effect of Osteocalcin in Middle-Aged Men with Erectile Dysfunction: Evidence from the FAMHES Project. Scientific Reports 8:1.
Crossref
Isaac CheruiyotBeda OlabuMartin KamauKevin OngetiPamela Mandela. (2018) Histomorphological changes in the common carotid artery of the male rat in induced hypogonadism. Anatomy & Cell Biology 51:4, pages 284.
Crossref
J. Vinay, J. Sarquella, J. Sanchez, F. Algaba, I. Gallegos, E. Ruiz-Castañe & C. Palma. (2017) Adipocyte accumulation in corpus cavernosum: First clinical evidence and pathophysiological implications in erectile dysfunction. Actas Urológicas Españolas (English Edition) 41:2, pages 97-102.
Crossref
J. Vinay, J. Sarquella, J. Sanchez, F. Algaba, I. Gallegos, E. Ruiz-Castañe & C. Palma. (2017) Acumulación de adipocitos en el cuerpo cavernoso: primera evidencia clínica e implicaciones fisiopatológicas en la disfunción eréctil. Actas Urológicas Españolas 41:2, pages 97-102.
Crossref
Marcello Maggio, Francesca De Vita, Fulvio Lauretani, Antonio Nouvenne, Tiziana Meschi, Andrea Ticinesi, Ligia J. Dominguez, Mario Barbagallo, Elisabetta Dall’Aglio & Gian Paolo Ceda. (2014) The Interplay between Magnesium and Testosterone in Modulating Physical Function in Men. International Journal of Endocrinology 2014, pages 1-9.
Crossref
Orcun Celik & Selcuk Yücel. (2013) Testosterone Replacement Therapy: Should It Be Performed in Erectile Dysfunction?. Nephro-Urology Monthly 5:4, pages 858-861.
Crossref
Inês Tomada, Nuno Tomada, Henrique Almeida & Delminda Neves. (2011) Androgen depletion in humans leads to cavernous tissue reorganization and upregulation of Sirt1–eNOS axis. AGE 35:1, pages 35-47.
Crossref
Maarten Albersen & Tom F. Lue. 2013. Prostate Cancer: A Comprehensive Perspective. Prostate Cancer: A Comprehensive Perspective 973 995 .
Mark R. Feneley & Malcolm Carruthers. (2012) Is Testosterone Treatment Good for the Prostate? Study of Safety during Long‐Term Treatment. The Journal of Sexual Medicine 9:8, pages 2138-2149.
Crossref
Maarten Albersen. (2011) Editorial Comment. Urology 77:6, pages 1386-1387.
Crossref
Tae-Young Shin, Ji-Kan Ryu, Hai-Rong Jin, Shuguang Piao, Munkhbayar Tumurbaatar, Guo Nan Yin, Sun Hwa Shin, Mi-Hye Kwon, Kang-Moon Song, Zheng-Huan Fang, Jee-Young Han, Woo Jean Kim & Jun-Kyu Suh. (2011) Increased Cavernous Expression of Transforming Growth Factor-β1 and Activation of the Smad Signaling Pathway Affects Erectile Dysfunction in Men with Spinal Cord Injury. The Journal of Sexual Medicine 8:5, pages 1454-1462.
Crossref
Sergio A. Moreno & Abraham Morgentaler. 2011. Contemporary Treatment of Erectile Dysfunction. Contemporary Treatment of Erectile Dysfunction 161 177 .
Abdulmaged M. Traish. (2010) Role of androgens in modulating male and female sexual function. Hormone Molecular Biology and Clinical Investigation 4:1.
Crossref
Sergio A. Moreno & Abraham Morgentaler. (2009) ORIGINAL RESEARCH—PEYRONIE'S DISEASE: Testosterone Deficiency and Peyronie's Disease: Pilot Data Suggesting a Significant Relationship. The Journal of Sexual Medicine 6:6, pages 1729-1735.
Crossref
Alvaro Morales. (2008) Commentary on Adjunctive Use of Testosterone Gel With Sildenafil for Erectle Dysfunction. Journal of Urology 179:5S.
Crossref
Malcolm Carruthers. (2008) The Paradox Dividing Testosterone Deficiency Symptoms and Androgen Assays: A Closer Look at the Cellular and Molecular Mechanisms of Androgen Action. The Journal of Sexual Medicine 5:4, pages 998-1012.
Crossref
A Armagan, K Hatsushi & P Toselli. (2007) The effects of testosterone deficiency on the structural integrity of the penile dorsal nerve in the rat. International Journal of Impotence Research 20:1, pages 73-78.
Crossref
Alvaro Morales. (2007) Testosterone Deficiency Syndrome in Males: Science and Politics. European Urology Supplements 6:17, pages 859-861.
Crossref
Abdulmaged M. Traish, Irwin Goldstein & Noel N. Kim. (2007) Testosterone and Erectile Function: From Basic Research to a New Clinical Paradigm for Managing Men with Androgen Insufficiency and Erectile Dysfunction. European Urology 52:1, pages 54-70.
Crossref
H O Goyal, T D Braden, P S Cooke, M A Szewczykowski, C S Williams, P Dalvi & J W Williams. (2007) Estrogen receptor-α mediates estrogen-inducible abnormalities in the developing penis. Reproduction 133:5, pages 1057-1067.
Crossref
Aksam A. Yassin, Farid Saad & Abdulmaged Traish. (2006) Testosterone Undecanoate Restores Erectile Function in a Subset of Patients with Venous Leakage: A Series of Case Reports. The Journal of Sexual Medicine 3:4, pages 727-735.
Crossref
Abdulmaged M. Traish & André T. Guay. (2006) REVIEWS: Are Androgens Critical for Penile Erections in Humans? Examining the Clinical and Preclinical Evidence. The Journal of Sexual Medicine 3:3, pages 382-407.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.