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Archives of Physiology and Biochemistry
The Journal of Metabolic Diseases
Volume 125, 2019 - Issue 1
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Original Article

Protective and anti-inflammatory effects of hydroalcoholic leaf extract of Origanum vulgare on oxidative stress, TNF-α gene expression and liver histological changes in paraquat-induced hepatotoxicity in rats

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Pages 56-63 | Received 26 Nov 2017, Accepted 01 Feb 2018, Published online: 09 Feb 2018

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Abiola S. Tijani, Olori O. David & Ebenezer O. Farombi. (2022) Manganese mitigates against hepatorenal oxidative stress, inflammation and caspase-3 activation in rats exposed to hexachlorobenzene. Drug and Chemical Toxicology 45:6, pages 2748-2757.
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Articles from other publishers (27)

Xiaogang Ge, Qiqi Cai, Sheng Zhang, Xianlong Wu, Pan Ying, Jingjing Ke & Zhihui Yang. (2023) Treatment with paraquat affects the expression of ferroptosis-related genes. Human & Experimental Toxicology 42, pages 096032712311675.
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Azza R. Elkholy, Ahmed R. El-Sheakh & Ghada M. Suddek. (2023) Nilotinib alleviates paraquat-induced hepatic and pulmonary injury in rats via the Nrf2/Nf-kB axis. International Immunopharmacology 124, pages 110886.
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Khang Wen Goh, Zulhisyam Abdul Kari, Wendy Wee, Nik Nur Azwanida Zakaria, Mohammad Mijanur Rahman, Muhammad Anamul Kabir, Noor Khalidah Abdul Hamid, Albaris B. Tahiluddin, Ahmad Syazni Kamarudin, Guillermo Téllez–Isaías & Lee Seong Wei. (2023) Exploring the roles of phytobiotics in relieving the impacts of Edwardsiella tarda infection on fish: a mini-review. Frontiers in Veterinary Science 10.
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Abiola S. Tijani, David O. Olori & Ebenezer O. Farombi. (2023) Manganese abated indomethacin-induced gastrohepatorenal toxicities in Rats via suppression of oxidative stress, polyamine catabolism, inflammation and activation of Caspase-3. Advances in Redox Research 8, pages 100070.
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Shanshan Qi, Beibei Lin, Sanqiao Wu, Hao Hao, Hongxin Zheng, Xiang Liu, Xiaoying Zhang, Lijuan Yue & Chen Chen. (2023) The hepatoprotective effect of Sophora viciifolia fruit extract against acetaminophen-induced liver injury in mice. Journal of Applied Biomedicine 21:2, pages 91-98.
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Aqsa Hanif, Samina Tanwir, Jam Nazeer Ahmad, Mansoor Hameed & Ghulam Mustafa. (2023) Nepeta paulsenii Briq. inhibits hepatic toxicity in albino rats: Phytochemical analysis and chemical profiling. Journal of King Saud University - Science 35:3, pages 102542.
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Sahar Rafiee, Ali Nouri & Esfandiar Heidarian. (2023) Role of NF‐κB/IL‐1β Pathway and Caspase 3 in Mediating the Hepatoprotective Effect of Rutin against Paraquat‐Induced Liver Toxicity in Male Rats. Chemistry & Biodiversity 20:4.
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Jiaqing Liao, Qiuxia Lu, Zhiqi Li, Jintao Li, Qi Zhao & Jian Li. (2023) Acetaminophen-induced liver injury: Molecular mechanism and treatments from natural products. Frontiers in Pharmacology 14.
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Soumia Beggah, Hasna Ellouzi, Lilya Boucelha, Walid Zorrig, Reda Djebbar & Ouzna Abrous-Belbachir. (2023) Ascorbate Attenuates Damages Caused by Paraquat-Induced Oxidative Stress in Fenugreek (Trigonella foenum-graecum L.) Seedlings. Journal of Soil Science and Plant Nutrition 23:1, pages 1185-1199.
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Parvaneh Mohseni‐Moghaddam, Manijeh Dogani, Motahare Hatami, Samira Roohollahi, Azam Amiresmaeli & Nayereh Askari. (2022) A behavioral and molecular study; ameliorated anxiety‐like behavior and cognitive dysfunction in a rat model of chronic unpredictable stress treated with oregano extract. Brain and Behavior 12:8.
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Li Jia, Jianping Wu, Yu Lei, Fanyun Kong, Rui Zhang, Jianxiang Sun, Liao Wang, Zemin Li, Jinping Shi, Ying Wang, Yubing Wei, Ke Zhang & Zhaomin Lei. (2022) Oregano Essential Oils Mediated Intestinal Microbiota and Metabolites and Improved Growth Performance and Intestinal Barrier Function in Sheep. Frontiers in Immunology 13.
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Mahdi Satvati, Najmeh Salehi-Vanani, Ali Nouri & Esfandiar Heidarian. (2022) Protective effects of N-acetyl cysteine against oxidative stress in ibuprofen-induced hepatotoxicity in rats. Comparative Clinical Pathology 31:2, pages 293-301.
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Norhashima Abd Rashid, Syarifah Aisyah Syed Abd Halim, Seong Lin Teoh, Siti Balkis Budin, Farida Hussan, Nurul Raudzah Adib Ridzuan & Nahdia Afiifah Abdul Jalil. (2021) The role of natural antioxidants in cisplatin-induced hepatotoxicity. Biomedicine & Pharmacotherapy 144, pages 112328.
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Luminita Capatina, Edoardo Marco Napoli, Giuseppe Ruberto & Lucian Hritcu. (2021) Origanum vulgare ssp. hirtum (Lamiaceae) Essential Oil Prevents Behavioral and Oxidative Stress Changes in the Scopolamine Zebrafish Model. Molecules 26:23, pages 7085.
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Ali Nouri, Farzad Izak-Shirian, Vahideh Fanaei, Maryam Dastan, Mahdieh Abolfathi, Alireza Moradi, Mansoor Khaledi & Hamzeh Mirshekari-Jahangiri. (2021) Carvacrol exerts nephroprotective effect in rat model of diclofenac-induced renal injury through regulation of oxidative stress and suppression of inflammatory response. Heliyon 7:11, pages e08358.
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Zahra Moslemi, Mina Bahrami, Ebrahim Hosseini, Mahboubeh Mansourian, Zahra Daneshyar, Mahdieh Eftekhari, Nasrin Shakerinasab, Arash Asfaram, Esmaeel Panahi kokhdan, Zahra Barmoudeh & Amir Hossein Doustimotlagh. (2021) Portulaca oleracea methanolic extract attenuate bile duct ligation-induced acute liver injury through hepatoprotective and anti-inflammatory effects. Heliyon 7:7, pages e07604.
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Ş. Abdullah ÖZDAŞÇI, Emin KAYMAK, Ali Tuğrul AKİN & Birkan YAKAN. (2021) The protective effect of Origanum majorana essential oil on gentamicin-induced nephrotoxicity in rats.Origanum majorana esansiyel yağının sıçanlarda gentamisin kaynaklı nefrotoksisite üzerindeki koruyucu etkisi. Bozok Tıp Dergisi.
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Izadpanah Gheitasi, Nikta Motaghi, Hossein Sadeghi, Heibatollah Sadeghi, Zahra Moslemi, Mahdieh Eftekhari, Nasrin Shakerinasab & Amir Hossein Doustimotlagh. (2021) Antioxidant and Anti-Inflammatory Effects of Origanum majorana L. Methanolic Extract on Bile Duct Ligation in Male Rats. Evidence-Based Complementary and Alternative Medicine 2021, pages 1-10.
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Alireza Moradi, Mahdieh Abolfathi, Mahsa Javadian, Esfandiar Heidarian, Hoshang Roshanmehr, Mansoor Khaledi & Ali Nouri. (2021) Gallic Acid Exerts Nephroprotective, Anti-Oxidative Stress, and Anti-Inflammatory Effects Against Diclofenac-Induced Renal Injury in Malerats. Archives of Medical Research 52:4, pages 380-388.
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Huanzhi Jin, Yingying Jiang, Wang Lv, Linglong Chen, Yanyan Zheng & Yue Lin. (2021) Gensenoside Rg1 protects against lipopolysaccharide- and d-galactose-induced acute liver failure via suppressing HMGB1-mediated TLR4-NF-κB pathway. Molecular and Cellular Probes 56, pages 101706.
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Mehdi Sharifi‐Rad, Yakup Berkay Yılmaz, Gizem Antika, Bahare Salehi, Tugba Boyunegmez Tumer, Chidambaram Kulandaisamy Venil, Gitishree Das, Jayanta Kumar Patra, Natallia Karazhan, Muhammad Akram, Mehwish Iqbal, Muhammad Imran, Surjit Sen, Krishnendu Acharya, Abhijit Dey & Javad Sharifi‐Rad. (2020) Phytochemical constituents, biological activities, and health‐promoting effects of the genus Origanum . Phytotherapy Research 35:1, pages 95-121.
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Asmaa F. Khafaga, Mohammed A.E. Naiel, Mahmoud A.O. Dawood & Hany M.R. Abdel-Latif. (2020) Dietary Origanum vulgare essential oil attenuates cypermethrin-induced biochemical changes, oxidative stress, histopathological alterations, apoptosis, and reduces DNA damage in Common carp (Cyprinus carpio). Aquatic Toxicology 228, pages 105624.
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ghader rahimzadeh, Mohamad Ali Azarbaijani & Hasan Matin Homaei. (2020) Comparing the effect of aerobic training, origanum vulgare extract supplementation and their combination on oxidative stress and inflammatory biomarkers on male rats. Medical Journal of Tabriz University of Medical Sciences and Health Services 42:3, pages 254-262.
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Marwa M. Abu-Serie, Noha H. Habashy & Adham M. Maher. (2019) In vitro anti-nephrotoxic potential of Ammi visnaga, Petroselinum crispum, Hordeum vulgare, and Cymbopogon schoenanthus seed or leaf extracts by suppressing the necrotic mediators, oxidative stress and inflammation. BMC Complementary and Alternative Medicine 19:1.
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Ali Nouri & Esfandiar Heidarian. (2019) Ameliorative effects of N ‐acetyl cysteine on diclofenac‐induced renal injury in male rats based on serum biochemical parameters, oxidative biomarkers, and histopathological study . Journal of Food Biochemistry 43:8.
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Ali Nouri & Esfandiar Heidarian. (2019) Nephroprotective effect of silymarin against diclofenac induced renal damage and oxidative stress in male rats. Journal of Herbmed Pharmacology 8:2, pages 146-152.
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Cheng Zhang, Ning Wang, Yu Xu, Hor-Yue Tan, Sha Li & Yibin Feng. (2018) Molecular Mechanisms Involved in Oxidative Stress-Associated Liver Injury Induced by Chinese Herbal Medicine: An Experimental Evidence-Based Literature Review and Network Pharmacology Study. International Journal of Molecular Sciences 19:9, pages 2745.
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